Promotor: Prof.dr. M. Franx, Co-Promotor: Rychard Bouwens

At the moment, over 350.000 chemicals are registered worldwide for production and use. Their application, however, may harm human health and the environment.

In this thesis, we use low-frequency and high-frequency radio observations to address the following questions regarding quasars: is the radio loud/quiet quasar dichotomy real?

A recent study on reintroduced tigers in Panna Tiger Reserve in India reveals that risks from tigers increased more because of human behaviour and people's livestock husbandry practices.

In-use stocks of products can be considered as intermediaries between human needs and the physical world.

Artificial intelligence algorithms govern in subtle, yet fundamental ways, the way we live and are transforming our societies. The promise of efficient, low‐cost or ‘neutral’ solutions harnessing the potential of big data has led public bodies to adopt algorithmic systems in the provision of public…

The focus of this thesis is how stars like our Sun and planets like Jupiter, Saturn, and Earth are formed.

In this work, we attempt to answer the question:

Promotor: E.F. Smets, Co-promotor: T.R. van Andel

The role of material production as a driver of environmental impacts is increasing, which calls for a better understanding of global material flows. This thesis explores the role of in-use stocks of products, buildings and infrastructure as a key driver of global material demand and discusses the implications…

This thesis describes the use of bioorthogonal proteins in immunological settings. It provides an introduction towards the field of protein modification, which was used throughout the thesis for the expression of proteins containing unnatural amino acids.

The studies presented in the work show the potential of the integrative use of biophysical data in defining the structural basis of protein interactions.

Prof.dr. P. Stevenhagen, Prof.dr. K. Belabas (Universite Bordeaux I)

Na het ontvangen van je diploma van LUC, kun je als alumni overal ter wereld heen. Velen die je voor zijn gegaan hebben ervoor gekozen om een master als vervolgopleiding te doen. Sommigen beginnen meteen aan hun professionele carrière of volgen een PhD. Door de vele academische vakgebieden die op LUC…

Aan de Universiteit Leiden worden cursussen over papyri en papyrologie aangeboden voor beginners en gevorderden (BA en MA), zowel op basis van teksten in vertaling als in de originele brontalen, van Egyptisch tot Grieks, Latijn en Arabisch.

Het aprilnummer van Leidschrift van 2014, 'Identiteit door strijd. Migranten en minderheden ten tijde van de Eerste Wereldoorlog' bevat bijdragen van verschillende stafleden van het Instituut voor Geschiedenis.

In the past decade many population studies have been performed with the Atacama Large Millimeter/submillimeter Array (ALMA) to understand the bulk properties of protoplanetary disks around young stars. These population studies mostly consisted of low mass stars, with relatively few of the disks around…

Lezing, Astronomy on Tap

Healthcare Information Systems (HIS) are essential for modern healthcare delivery, yet their development faces significant challenges including heterogeneous data formats, regulatory compliance, and the growing demand for AI-driven decision support.

This thesis describes the synthesis and biochemical evaluation of a variety of cyclophellitol based activity-based probes and inhibitors targeting various endo- and exo-acting retaining glycosidases. In the last two decades a variety of probes and inhibitors for (hemi)cellulose degrading enzymes have…

In this Ph.D. thesis we study the interaction of low energy electrons with thin materials, namely layered materials (graphene, hexagonal boron nitride, molybdenum disulfide) and organic films. At these low energies the quantum mechanical wavelength of the electron wave function is in the order of a…

We use DNA strands to stabilize few-atom silver clusters, which show unique optical and chemical properties. This thesis involves the study of these constructs for various applications.

The aim of this thesis is to develop and study a robust and adaptable scaffold for supramolecular polymer self-assembly in water.

In this thesis, we developed new ways to use a technique called electroextraction (EE) to extract charged molecules from one liquid into another using an electric field.

In this thesis, we have studied cell images from two types of cells, including pollen grains and the immune cells, neutrophils. These images are captured using a bright field microscope and a confocal microscope.

The International Course on Water Use and Management in Cagayan Valley The Philippines (2011-2015)

The global agri-food system plays a critical role in food security and environmental issues.

CML-IA is a database that contains characterisation factors for life cycle impact assessment (LCIA) and is easily read by the CMLCA software program.

Microbial rhodopsins are photosensitive pigments implemented in the growth and adaptation of a large population of microorganisms.

During the development of the (human) body from a single fertilized egg, organs and structures must form. The development and growth of biological forms is called morphogenesis.

In this thesis, deep learning is studied from a statistical perspective. Convergence rates for the worst case risk bounds of neural network estimators are obtained in the classification, density estimation and linear regression model.

Ferritin is a spherical metalloprotein, capable of storing and releasing iron in a controllable way. It is composed of a protein shell of about 12 nm and within its cavity, iron is stored in a mineral form.

Promotor: Prof.dr. C.W.J. Beenakker

Global healthcare is on the verge of an antibiotic availability crisis as bacteria have evolved resistance to nearly all known antibacterials. Identifying new antibiotics that operate via novel modes-of-action is therefore of high priority.

Surface acoustic waves (SAWs) are mechanical waves that travel along the surface of a material and find many applications in modern technologies due to the ease of excitation on piezoelectric substrates via interdigital transducers (IDTs).

Promotores: Prof.dr. E.F. van Dishoeck, Prof.dr. C.P. Dullemond

A dense region of a gaseous and dusty cloud collapses to form a protostar surrounded by a disk and an envelope. This thesis uses both observations and models to study physical and chemical conditions of these protostellar systems which are likely where planets start to form.

Promotor: Prof.dr. W.T.F. den Hollander

Pulsars were first discovered in 1967 and since then the population has grown and expanded over several wavelengths.

SDN (Software-Defined Networking) represents a revolutionary approach to network architecture that enables the dynamic and flexible management of network resources through software-based control. This dissertation introduces the idea of SDN and its southbound protocol OpenFlow, then presents the formal…

Promotor: G.P. van Wezel, Co-Promotor: E. Vijgenboom

The focus throughout this thesis will be on gathering fundamental studies of the detailed structure and composition of the electrode/electrolyte interface effect on the rate and mechanism of key electrocatalytic reactions.

The endocannabinoid receptors CB1R and CB2R are involved in a plethora of processes, and consequently are involved in many pathological conditions. Their wide distribution makes the CBRs both an interesting therapeutic target and hard to study.

Promotor: Prof.dr. F. den Hollander, G.Maillard

Of all the mass in our Universe, 80% is thought to consist of a hypothetical and invisible substance called dark matter (DM).

Materials with strongly correlated electrons show some of the most mysterious and exotic phases of quantum matter, such as unconventional superconductivity, quantum criticality and strange metal phase.

Human language is constantly evolving with its linguistic structure being shaped by language users at both individual and population levels. Focusing on the interplay between processes of language acquisition and communicative need in shaping human languages, this thesis introduces a novel computational…

In this dissertation non-parametric Bayesian methods are used in the application of robotic vision.

Promotor: G.A. Persoon, Co-promotor: H.H. de Iongh