430 zoekresultaten voor “labour make” in de Publieke website
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Signalling pathways that control development and antibiotic production in streptomyces
Bacteria are highly complex and diverse organisms that have adapted to survive in ecological niches ranging from the most extreme to the most heterogeneous environments.
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Getting personal: Advancing personalized oncology through computational analysis of membrane proteins
Cancer is considered the silent pandemic of the 21st century and the second leading cause of death worldwide.
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Infrared spectroscopy of astrophysically relevant hydrocarbons
This thesis is about the study of hydrocarbons via infrared spectroscopy.
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Improving robustness of tomographic reconstruction methods
Promotor: Prof.dr. K.J. Batenburg
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Better Predictions when Models are Wrong or Underspecified
Promotor: P.D. Grünwald
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A new method to reconstruct the structure from crystal images
Promotor: J.P. Abrahams, Co-promotor: T. Grüne
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Sofia Express
In Sofia Express gaat Jan Paul Hinrichs op zoek naar de literaire geheimen van de Bulgaarse hoofdstad Sofia, een stad waarin detectives, spionage en andere intriges nooit ver weg zijn.
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Development of highly accurate density functionals for H2 dissociation on transition metals
Metals surfaces form a group of effective catalysts for the reaction of small molecules such as hydrogen (H2).
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Modular curves, Arakelov theory, algorithmic applications
Promotor: S.J. Edixhoven, Co-promotor: R.S. de Jong
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Principles of Environmental Sciences
Principles of Environmental Sciences provides a comprehensive picture of the principles, concepts and methods that are applicable to problems originating from the interaction between the living and non-living environment and mankind. Both the analysis of such problems and the way solutions to environmental…
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Granular Flows: Fluidization and Anisotropy
Promotor: Prof.dr. M.L. van Hecke
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Aria of the Dutch North Sea
Promotores: C. J. ten Cate; M. A. Ainslie. Co-promotor: W. Slabbekoorn
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Electrical and magnetic properties of ferritin: electron transport phenomena and electron paramagnetic resonance
Ferritin is a spherical metalloprotein, capable of storing and releasing iron in a controllable way. It is composed of a protein shell of about 12 nm and within its cavity, iron is stored in a mineral form.
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Liposome-based synthetic long peptide vaccines for cancer immunotherapy
Promotores: Wim Jiskoot; Ferry Ossendorp
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Social network and radical innovation: evidence from the U.S. pharmaceutical and biotechnology industry
Innovation plays an essential role in firms' competitiveness and long-term success. It varies from different types, ranging from run-of-the-mill innovation that brings incremental changes to existing technologies to radical innovation that breaks from existing trajectories.
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Modelling the interactions of advanced micro- and nanoparticles with novel entities
Novel entities may pose risks to humans and the environment. The small particle size and relatively large surface area of micro- and nanoparticles (MNPs) make them capable of adsorbing other novel entities, leading to the formation of aggregated contamination.
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RAISE Onderzoek
Het doel van het RAISE Onderzoek is om te onderzoeken hoe veerkrachtige mensen omgaan met stress. We kijken specifiek naar hoe belangrijke biologische systemen, zoals de HPA-as en het immuunsysteem, samenwerken met de hersenen en de sociale omgeving om veerkrachtig functioneren na moeilijkheden in de…
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Network flow algorithms for discrete tomography
Promotor: R. Tijdeman, Co-promotor: H.J.J. te Riele
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Substrate adaptability of β-lactamase
The research aims to explore the evolutionary adaptability of enzymes and the impact of temperature on protein evolution pathways, using M. tuberculosis β-lactamase BlaC as the object of study. Enzymes inherently embody a delicate balance between activity and stability, and the acquisition of new enzymatic…
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Understanding deep meta-learning
The invention of neural networks marks a critical milestone in the pursuit of true artificial intelligence. Despite their impressive performance on various tasks, these networks face limitations in learning efficiently as they are often trained from scratch.
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Atomic Insights into Hydrodesulfurization
Hydrodesulfurization (HDS) is an ubiquitous part of oil refining that ensures that fuels are cleaned of impurities and environment release of pollutants such as SOx and NOx gasses are minimized.
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Exploring structure dependencies of gas-surface interactions with curved single crystals
Curved single crystals provide variable, but well-defined surface structures.
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How lawyers win land conflicts for corporations: Legal Strategy and its influence on the Rule of Law in Indonesia
Op 23 juni 2020 verdedigde Santy Kouwagam haar proefschrift 'How lawyers win land conflicts for corporations: Legal Strategy and its influence on the Rule of Law in Indonesia'. Het promotieonderzoek is begeleid door promotoren prof.dr. A.W. Bedner en prof.dr. C.E. von Benda-Beckmann.
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Analysis of Energy Systems
The Institute of Environmental Sciences has carried out and participates in several projects that deal with the analysis of energy systems.
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Design and development of a comprehensive data management platform for cytomics: cytomicsDB
Promotor: Prof.dr. J.N. Kok
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How Electrostatic Interactions Drive Nucleosome Binding of RNF168 & PSIP1
The studies presented in the work show the potential of the integrative use of biophysical data in defining the structural basis of protein interactions.
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Automata-theoretic protocol programming
Promotor: F. Arbab
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Using soil inoculations for ecological restorations
How soil microbial composition impacts structure and composition of the aboveground plant and animal communities?
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The electrode-electrolyte interface in CO2 reduction and H2 evolution: a multiscale approach
Electrocatalysis allows for storing electricity or converting it into chemical bonds, producing chemical building blocks and fuels using renewable resources.
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Toll-like receptor signaling in the innate immune system of zebrafish larvae
Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez
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Electroextraction approaches for preconcentration of metabolites
In this thesis, we developed new ways to use a technique called electroextraction (EE) to extract charged molecules from one liquid into another using an electric field.
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Exploring and exploiting the mechanism of mycelial pellet formation by Streptomyces
Promotor: G.P. van Wezel
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Multi-Objective Bayesian Global Optimization for Continuous Problems and Applications
A common method to solve expensive function evaluation problem is using Bayesian Global Optimization, instead of Evolutionary Algorithms.
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PNEC-pro
PNEC-pro is a user-friendly screening tool for professionals dealing with the assessment of surface water quality. The tool calculates local, watertype specific no-effect concentrations (PNEC) of copper, lead, nickel and zinc based on biotic ligand models (BLMs).
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Exploring the metabolism and toxicity of amino sugars and 2-deoxyglucose in Streptomyces
Streptomyces are prolific producers of enzymes and secondary metabolites, including more than 50% of all clinical antibiotics. This makes them highly attractive for medical, biotechnological, and industrial purposes.
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On transport properties of Majorana fermions in superconductors: free & interacting
Majorana fermions in superconductors are the subgap quasiparticle excitations that are their own antiparticles.
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Identification and characterization of viral Xrn1-resistant RNAs
Several single-stranded RNA viruses make use of Xrn1-resistant RNAs in their 3’ untranslated regions of their genome RNAs in order to increase their pathogenicity.
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Opportunity and Problem in Context (OPiC). A framework for environmental management in developing countries
Promotor: W.T. de Groot
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Affinity-based profiling of the adenosine receptors
The adenosine receptors are proteins that reside in the extracellular membranes of cells. Activation of adenosine receptors plays a role in many physiological and pathological processes, such as immune responses and cancers.
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Origami metamaterials : design, symmetries, and combinatorics
In the first part of this thesis we study the geometry of folding patterns.
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Using cryo-EM methods to uncover structure and function of bacteriophages
Bacteriophages, or phages for short, are the most abundant biological entity in nature. They shape bacterial communities and are a major driving force in bacterial evolution.
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The Regime for International Air Carrier Liability
Op 17 november 2021 verdedigde Cyril-Igor Grigorieff het proefschrift 'The Regime for International Air Carrier Liability'. Het promotieonderzoek is begeleid door prof.dr. P. Mendes de Leon en prof.dr. V. Correia (University Paris Saclay).
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Rationally designed peptide based functional biomaterials
Promotor: Prof.dr. J.G.E.M. Fraaije, Co-promotor: A. Kros
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On the optimization of imaging pipelines
In this thesis, topics relating to the optimization of high-throughput pipelines used for imaging are discussed. In particular, different levels of implementation, i.e., conceptual, software, and hardware, are discussed and the thesis outlines how advances on each level need to be made to make gains…
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Development of new chemical tools to study the cannabinoid receptor type 2
The endocannabinoid receptors CB1R and CB2R are involved in a plethora of processes, and consequently are involved in many pathological conditions. Their wide distribution makes the CBRs both an interesting therapeutic target and hard to study.
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Quantification in untargeted mass spectrometry-based metabolomics
Promotor: T. Hankemeier, Co-promotor: T.H. Reijmers
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Big simulations for big problems
In this thesis we investigate cosmology and the large scale structure of the Universe using cosmological simulations.
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Using commitment to improve environmental quality
Promotores: E. van Dijk, G.R. de Snoo. Co-promotor: H. Staats
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Semi-partitioned Scheduling and Task Migration in Dataflow Networks
Promotor: Ed F. Deprettere, Co-promotor: Todor P. Stefanov
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Collateral Transactions and Shadow Banking
Op 13 oktober 2021 verdedigde Ross Spence het proefschrift 'Collateral Transactions and Shadow Banking'. Het promotieonderzoek is begeleid door promotoren prof.mr. M. Haentjens en prof.dr. A.M. Pacces (UvA).