This thesis is a (biased) journey through very different topics in astrophysics: quasars and new populations of active galactic nuclei, gravitational waves from merging black holes, and protoplanetary discs around young stars.

Promotor: J.S. Kaastra Co-promotor: E. Constantini

Promotor: Prof.dr. B.R. Katzy, Prof.dr. H.J. van den Herik, Prof.dr. G.H. Baltes (University of Applied Sciences Konstanz)

Promotores: Prof.dr. G.W. Canters, Prof.dr. T.J. Aartsma

In this thesis, the role of mast cells in atherosclerosis and novel therapeutic strategies to inhibit atherosclerosis progression are discussed. The first part of the thesis specifically focuses on the relation between mast cells and advanced human atherosclerotic plaque characteristics.

Classical statistical methods, such as p-values, are difficult for researchers to apply correctly. They for example do not allow drawing conclusions from a study early, or for extending a study with extra research groups that want to make their data available later.

Promotor: Jaap Brouwer, Co-promotor: Remus Th. Dame

In februari 2014 werd in Zwitserland een constitutioneel initiatief over de begrensing van immigratie aangenomen. Deze begrensing moet gebeuren door middel van quota’s op het gebied van werk en nationale voorrang toe te passen.

In this thesis, I focused on studying the above- and belowground interactions of J. vulgaris from a plant-soil feedback (hereafter, PSF) perspective. I investigated the temporal variation of negative PSF and examined the effects of root-associated bacteria on plant performance and aboveground herbiv…

Op 12 november verdedigde Clare Fenwick het proefschrift 'The political economy of immigration and welfare state reform: a collection of comparative political and economic essays on human mobility and social protection'. Het promotieonderzoek is begeleid door Olaf van Vliet en Kees Goudswaard.

A single self-assembled semiconductor quantum dot in a high-finesse optical microcavity - the subject of this thesis - is an interesting quantum-mechanical system for future quantum applications. For instance, this system allows trapping of an extra electron and thus can serve as a spin quantum memory,…

Nanoparticles can be used as delivery systems for both small molecules and macromolecules such as proteins, peptides or oligonucleotides. This thesis focuses on the use of liposomes, nanometric vesicles formed by a lipid bilayer enclosing an aqueous core. Liposomes are highly versatile delivery syst…

Na de hoorzittingen over de Toeslagenaffaire, had de Tweede Kamer behoefte om zich door deskundigen te laten adviseren over alternatieven voor het toeslagenstelsel. Hierover vond een rondetafelgesprek plaats op woensdag 2 december 2020 in het gebouw van de Tweede Kamer.

This pioneering project will answer this question by examining migrants through the eyes of the courts between 1600 and 1900. It aims to reveal patterns of continuity and change in: 1. Treatment of migrants by criminal courts; 2. Violence and conflicts between migrants and native born.

Wat kunnen de talen die vandaag gesproken worden op de Kleine Soenda-eilanden ons vertellen over de geschiedenis van de verschillende bevolkingsgroepen?

Plants and soils from natural ecosystems harbor great diversity of soil microorganisms, which could potentially contribute to the sustainability of horticulture. The knowledge about using wild plant species and soil from natural ecosystem to improve the crop health will advance the application of ecological…

Tijdens de zestiende en zeventiende eeuw vestigden zich ongeveer 600.000 buitenlanders in de steden van de provincie Holland in de Nederlandse Republiek. Het is algemeen bekend dat het vroegmoderne Amsterdam, in het bijzonder, een constant grote migrantenpopulatie aantrok. De religieuze tolerantie,…

This thesis seeks to investigate how cancer-associated mutations affect the pharmacological properties of selected GPCRs—primarily A2AAR and 5-HT2CR—through a combination of ligand binding assays, signaling readouts, kinetic profiling, and cellular functional assays.

Over the past years it has been discovered that the population of extra-solar planets is large and diverse.

We have studied shape with a particular focus on the zebrafish model system. The shape is an essential appearance of the phenotype of a biological specimen and it can be used to read out a current state or response or to study gene expression.

Throughout the history of computer science, a major challenge has been how to assert that software is free of bugs and works as intended. Software bugs can lead to serious negative impacts on any software system. Throughout the main body of the thesis, we implemented a series of studies on exploring…

Electoral Systems and Turnout: Evidence From a Regression Discontinuity Design. In dit artikel, gepubliceerd op de website SAGE research methods, bespreken auteurs Jaroslaw Kantorowicz en Tobias M. Hlobil hoe een Regression Discontinuity Design uitgevoerd kan worden.

Promotor: Prof.dr. A.G.G.M. Tielens, Prof.dr. C. Dominik (UvA)

This Thesis describes the synthesis of D-alanylated ribitol-based wall teichoic acids from S. aureus to probe their interaction with immune-binding partners.

This dissertation presents new cryptographic protocols, which can be divided into two families.

The investigations described in this thesis lay out strategies aimed at advancing antibiotic research and development. The examples presented revolve around two main approaches: understanding drug-target interactions and target identification.

This thesis addresses the chemical processes that determine the compositions of giant planet atmospheres.

Promotor: H.J.A. Röttgering, Co-promotor: M. Haverkorn

Prematurely born neonates require, amongst others, pharmaceutical therapy. Dosing guidelines for these therapies are often based on data from term born neonates or older infants, while these are not necessarily similar to prematurely born neonates.

Promotores: Prof.dr. J. Zaanen, Prof.dr. K.E. Schalm

This thesis presents insights from our study of various correlated electron systems with a scanning tunneling microscope (STM). In ordinary metals, electron-electron interactions exist, but get substantially screened due to the sheer number of electrons.

Streptomyces are bacteria abundant in soil that participate in diverse and complex interactions. These bacteria are the main producers of the antibiotics we currently use in the clinic.

In dit artikel onderzoeken Thijs van Dooremalen en Philip Smith hoe het publieke discours over hittegolven is verschoven in Britse kranten.

Lezing

Leo Lucassen, hoogleraar Global Labour and Migration History aan de Universiteit Leiden, was te gast bij Radio1 om te spreken over zijn nieuwe (herziene) boek: ‘Vijf eeuwen migratie: een verhaal van winnaars en verliezers’.

Stichting Migratierecht Nederland en het Europa Instituut van de Universiteit Leiden organiseren gezamenlijk het congres Kinderrechten en migratie dat zal plaatsvinden op 26 januari 2023 te Leiden. Op het congres zullen wetenschappers, advocaten, rechters, beleidsmaker, en andere professionals uit de…

The global agri-food system plays a critical role in food security and environmental issues.

Promotor: Prof.dr. M. Danhof, Co-promotor: O.E. Della Pasqua

Irene Khan, expert op het gebied van mensenrechten, werpt een aantal vragen op: Wat kan men verstaan onder een ‘Culture of Justice’? Wie bepaalt wat 'Justice' is? Hoe realistisch is de bevordering van ‘Rule of Law’ en ‘Justice’ in landen waar sprake is van ernstige conflictsituaties en armoede?

Due to its economic prosperity, its policy of (relative) religious tolerance, and its large numbers of migrants, the Dutch Republic has long had a reputation of being the prime example of ‘tolerance’, especially during the seventeenth century. Although the great variety of newcomers in the Dutch Republic…

Onder deze noemer vond op 8, 9 en 10 maart jl. in Hanoi (Vietnam) de slotconferentie van het ANRC programma plaats.

Met ingang van 1 januari 2019 is er vanuit het Van Vollenhoven Instituut gestart met een onderzoek naar gastvrijheid en migratie.

Zo’n beetje alles over Charles Darwin is inmiddels wel geschreven of gezegd. Toch wist Norbert Peeters – samen met Tessa van Dijk – alsnog een origineel boek te schrijven over de grote Engelse geleerde. In aanloop naar Darwindag (12 februari) vertelt hij erover.

Onder welke omstandigheden kan dwangdiplomatie een staat dwingen zijn kernwapenprogramma op te geven?

With an emphasis on developing novel miktoarm star polymers termed PeptoMiktoStars, this thesis leverages asymmetric polymeric polypept(o)ide frameworks to advance their effectiveness in delivering hydrophobic drugs and nucleic acids.