De Universiteit Leiden stimuleert studenten om na hun bacheloropleiding door te gaan met de masteropleiding. Je Leidse bachelordiploma Psychologie geeft je toegang tot de masteropleiding Psychologie in Leiden.

Een onderzoek naar hoe mensen eten en drinken tijdens hun dagelijkse routines, en onder welke omstandigheden dit plaatsvindt.

Promotor: C.J. ten Cate

Humans can see the world through the eyes of other humans and imagine what they know, want, and intend. This competence is known as Theory of Mind.

Nieuw onderzoek van de National University of Singapore en Leiden laat zien dat chimpansees en bonobo’s net zoveel contrast in hun ogen hebben als mensen, waardoor ze gemakkelijk de richting van iemands blik kunnen volgen.

Jan Sleutels is een Universitair hoofddocent aan het Instituut voor Wijsbegeerte.

Welk effect heeft een verwerkingsvoorkeur op de omgang met regels?

African oral literatures, new media and technologies: challenges for research and documentation

Op 16 december 2021 verdedigde Lisanne van Houten het proefschrift 'Flexing the Slot Regime'. Het promotieonderzoek is begeleid door prof.dr. P. Mendes de Leon en prof. L. Pierallini (Luiss University Of Rome).

In this thesis, deep learning is studied from a statistical perspective. Convergence rates for the worst case risk bounds of neural network estimators are obtained in the classification, density estimation and linear regression model.

Promotores: J. Zaanen, A. Parnachev

Despite the fact that gold nanoparticles (GNPs) are one of the most studied nanoparticles, there is still a necessity for new approaches allowing for effective protective coating to enable wider use of GNPs in biomedical applications.

The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.

Promotor: E.F. Smets, Co-promotor: J. Geml

Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt

The progressive loss and degeneration of dopaminergic neurons is a major pathological hallmark of Parkinson's disease (PD). The onset and progression of PD can be triggered by multiple risk factors, for instance, genetic mutation, environmental exposure, and aging.

The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.

This thesis aims to enhance our understanding of galaxies by testing theoretical models of galaxy formation against observations, particularly in the cases of extreme systems which have been found to have an excess of baryonic mass in their central regions, in the form of either supermassive black holes…

Galaxies in the local Universe fall into two main categories of spirals and ellipticals. In this Thesis, we explore the structural evolution of galaxies into this bimodal distribution.

The thesis is about how auxin and AGC kinases regulate male fertility. The main AGC kinases studied in this thesis is PDK1, PDK2 and AGC1.5, AGC1.7.

The research described in this thesis shows that hypercholesterolemia, a well-established risk factor for atherosclerosis, can impact skin lipid pool and barrier function already at young age. In the field of atherosclerosis, we showed that the small peptide Lyp-1 can be used as a targeting molecule…

This thesis describes the development and optimization of the first molecular tools to study the enzyme PLA2G4E.

Carbon dioxide capture and utilization technologies are necessary to create a truly circular economy. The electrochemical reduction of carbon dioxide to formate is an appealing carbon utilization method as it can be performed at room temperature and pressure, it only requires two electrons, and it has…

The CC chemokine receptor 2 (CCR2), a member of the G protein-coupled receptor (GPCR) superfamily, is widely involved in autoimmune and inflammatory diseases. However, no drugs for this receptor have made it to the pharmaceutical market yet.

The human body consists of hundreds, perhaps thousands of different types of cells, each with different morphologies and functions, despite having the same genome.

The objective of this study was to investigate the expression and function of GRHL2 in different breast cancer subtypes.

Promotor: V. Vitelli, Co-promotor: J. Paulose

A modern ship design process is subject to a wide variety of constraints such as safety constraints, regulations, and physical constraints.

Plant exudates appeared long time ago in the history line of life in the early Devonian. They are typical saps produced by specialized cells.

Throughout the history of computer science, a major challenge has been how to assert that software is free of bugs and works as intended. Software bugs can lead to serious negative impacts on any software system. Throughout the main body of the thesis, we implemented a series of studies on exploring…

In this thesis, we study different curved single crystals because of the diversity of surface structures across their curvature.

This thesis advances our understanding of lipid uptake, a vital first step in lipid metabolism, by developing innovative click chemistry-based tools to study how immune cells internalize lipids.

There are many interpretations of quantum mechanics, and ultimately experiments are needed to verify or falsify these interpretations.

Solar energy is used by photosynthetic organisms to drive energy required cellular processes. Is absorbed by two groups of pigments, located in the LHCs.

Drug induced organ toxicity is the main problem of the drug development and drug usage in the clinic. The liver and kidneys are the most sensitive organs towards drug induced toxicity.

M. Danhof, Co-promotores: J. Freijer, A. Yassen

Promotor: S.M. Verduyn Lunel, Co-promotor: S.C. Hille

Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn Co-promotor: Dr. M.J.M. Schaaf

Promotor: Prof.dr. G.R. de Snoo, Prof.dr. G.A. Persoon, Co-promotor: H.H. de Iongh

Promotor: Prof.dr. D. Bouwmeester

This dissertation presents new cryptographic protocols, which can be divided into two families.

Due to their central physiological roles in living organisms, retaining beta-glycosidases have been the subject of tremendous research efforts to examine their structure/function relation using numerous biophysical and biochemical approaches.

Atherosclerosis is the main underlying pathology of cardiovascular disease. Atherosclerosis is caused by an immune response which is directed against (modified) lipoproteins which accumulate in the vessel wall.

Growth and development affect the metabolism of drugs administered to neonates, infants, and children.

Promotor: M.K. Richardson, Co-Promotor: F. Witte

The effective treatment of tuberculosis (TB) remains a major challenge to global health.

The lysosomal β-glucosidase named glucocerebrosidase (GCase) is a retaining β-glucosidase that hydrolyzes the glycosphingolipid glucosylceramide (GlcCer) to ceramide and glucose at acid pH.

The spindle-assembly checkpoint (SAC) is a safety mechanism which secures accurate chromosome segregation during mitosis.

Synthesis and application of chemical biology tools to study immunomodulatory signaling lipids.

Streptomyces are filamentous bacteria that produce more than two-thirds of known antibiotics.