I will give a general introduction to the field of molecular electronics, its history, methods and challenges. I will also introduce the subject of my investigation and provide a brief outlook to the remainder of our thesis.

Promotor: E. F. van Dishoeck, Co-promotor: C. Walsh

This thesis has three main parts. The first part gives an algorithm to compute Hilbert modular polynomials for ordinary abelian varieties with maximal real multiplication. Hilbert modular polynomials of a given level b give a way of finding all of the abelian varieties that are b-isogeneous to any given…

Promotor: Peter Stevenhagen

Promotor: A.H. Meijer, Co-promotor: B.E. Snaar-Jagalska

Het aantal planeten waarop complex leven kan gedijen, is kleiner dan gedacht. Beloftevolle tweelingen van de aarde blijken bij nader inzien slechts beperkt levensvatbaar, stellen astronomen. Ignas Snellen van de Leidse Sterrewacht reageert in DeMorgen op het nieuws.

Promotor: Prof.dr. V. Icke, Co-Promotor: T.I. Madura

De auteurs zoeken en beoordelen systematisch relevante definities van Security by Design (SbD) in vergelijking met Privacy by Design (PbD).

Dit proefschrift omvat vier deelstudies naar de inhoud en structuur van de opvattingssystemen van natuurkundedocenten over het leren en onderwijzen van natuurkunde in het voortgezet onderwijs (VO) in Nederland.

Technologies that help to enhance our educational environments can be found everywhere.

Ben Wielstra onderzoekt balanced lethal systems, waarin de helft van het nageslacht al voor de geboorte sterft. In vakblad Current Biology legt hij op toegankelijke wijze uit hoe zoiets nadeligs kan ontstaan in de natuur.

Accurate prediction of the unbound drug concentration-time profile at the CNS target site is crucial for the assessment of the right drug concentration-effect relationship. PBPK models have supported the PK prediction of the CNS target sites and the translation of PK data between species and between…

Artificial photosynthesis has recognised potential to produce green and sustainable fuels from earth-abundant resources such as water, carbon dioxide (CO2), and sunlight.

SDN (Software-Defined Networking) represents a revolutionary approach to network architecture that enables the dynamic and flexible management of network resources through software-based control. This dissertation introduces the idea of SDN and its southbound protocol OpenFlow, then presents the formal…

The research described in this thesis has, using the zebrafish as a model system, shed new light on the intricate relationship between TB and DM2, in particular on the role of leptin, SHP-1 and glucocorticoids.

Op 15 en 16 december nam Simona Demková deel aan een afsluitende conferentie en boekpresentatie van het doctorale opleidingsprogramma van de Universiteit van Luxemburg over ‘Enforcement Challenges in Multilevel Regulatory Systems – DTU REMS.

Sinds de gasbevingen in Groningen worden ‘vertrouwen’ en ‘overheid’ daar niet zomaar meer met elkaar geassocieerd. Dat leverde de casus op van de Honours Class ‘Gaswinning in Groningen en het fenomeen van vertrouwen in de overheid’, waarin studenten erachter kwamen hoe complex een begrip als ‘vertrouwen’…

Promotores: Prof.dr. J. Kuiper, Prof.dr. P.H.A. Quax, Co-promotor: I. Bot

Light-Harvesting Complex II (LHCII) is responsible for light absorption and excitation energy transfer in plants and photosynthetic algae, while in high light it undergoes conformational changes by which it quenches excitations to prevent photodamage.

A large diversity of exoplanetary systems has been found, but it is still unclear what drives this diversity.

Promotor: P. J. J. Hooykaas Co-promotor: B. S de Pater

Promotor: Prof.dr. E. Deprettere

Actinobacteria are Gram-positive bacteria that have a complex multicellular life cycle and are well known for their ability to produce a wide range of bioactive natural products (NPs).

In deep reinforcement learning, searching and learning techniques are two important components. They can be used independently and in combination to deal with different problems in AI, and have achieved impressive results in game playing and robotics. These results have inspired research into artificial…

The database research community has made tremendous strides in developing powerful database engines that allow for efficient analytical query processing.

By training with virtual opponents known as computer generated forces (CGFs), trainee fighter pilots can build the experience necessary for air combat operations, at a fraction of the cost of training with real aircraft.

Research

Prof. Ton Liefaard en dr. Stephanie Rap (m.m.v. Apollonia Bolscher LL.M.) zijn betrokken bij het ontwikkelen van een training Toolkit en Manual voor het project Improving Juvenile Justice Systems in Europe: Training for Professionals (JUST/2013/FRC/AG).

The progressive loss and degeneration of dopaminergic neurons is a major pathological hallmark of Parkinson's disease (PD). The onset and progression of PD can be triggered by multiple risk factors, for instance, genetic mutation, environmental exposure, and aging.

The largest genus within the Phyllanthaceae family is a group called Phyllanthus L. Recent studies have shown, that Phyllanthus is paraphyletic with the genera Glochidion, Breynia and Synostemon nested within it.

Hoe kan complexiteitswetenschap de transformatie van inlichtingen bevorderen?

In this thesis chemical and physical processes in the ice mantles on interstellar dust grains are studied.

Het Data Science Onderzoeksprogramma (DSO) combineert Leidse promotieonderzoeken uit allerlei disciplines met data science. Het programma loopt nu ruim twee jaar, en levert verrassende eerste resultaten op. Hieronder vertellen een aantal promovendi over hun ervaringen en hun onderzoek.

De VVD stemde vorige week in met de nieuwe spreidingswet, waardoor gemeentes verplicht kunnen worden asielzoekers te huisvesten. Dat gebeurde nadat premier Rutte toezegde aan de slag te gaan met het inperken van de stroom asielzoekers. In hoeverre kan hij die belofte waarmaken?

Promotor: Prof.dr. G.P. van Wezel

Promotor: A. Kros, Co-promotor: R.R.C.L. Olsthoorn

Promotor: W.Th.F. den Hollander, Co-promotor: F.R. Nardi

Climate change is a challenge for both current and future generations. New biological resources have to be developed in order to meet the demand for energy as well as the demand for food.

Theoretisch natuurkundigen Kevin Grosvenor en Sam Young hebben Marie Curie-beurzen toegekend gekregen voor onderzoek aan het Instituut Lorentz.

Promotor: Ed F. Deprettere, Co-promotor: Todor P. Stefanov

Surface acoustic waves (SAWs) are mechanical waves that travel along the surface of a material and find many applications in modern technologies due to the ease of excitation on piezoelectric substrates via interdigital transducers (IDTs).

This thesis is largely an experimental study on the formation of solid-state simple and complex organic molecules in the H2O-rich and CO-rich ice phases of dense interstellar clouds and dark cores.

To an algebraic curve C over the complex numbers one can associate a non-negative integer g, the genus, as a measure of its complexity.

Metamaterialenonderzoeker Martin van Hecke was onderwerp van een reportage in Atlas, het NTR-televisieprogramma over wetenschap en actualiteit.

Femke Bakker, Hawks and Doves: Democratic Peace Theory Revisited

This thesis focuses on enhancing predictions of central nervous system drug exposure using the LeiCNS-PK3.0, a physiologically based pharmacokinetic model.