Promotor: Prof.dr. E.F. Smets. Co-promotores: B. Gravendeel, F. Pupulin

The investigations described in this thesis lay out strategies aimed at advancing antibiotic research and development. The examples presented revolve around two main approaches: understanding drug-target interactions and target identification.

The research described in this thesis has, using the zebrafish as a model system, shed new light on the intricate relationship between TB and DM2, in particular on the role of leptin, SHP-1 and glucocorticoids.

How and to what extent the historic house (re-)constructs identity through image-making in China.

Hieronder vind je een overzicht van hoe onderzoekers van de faculteit Governance and Global Affairs en hun onderzoeken in de media verschijnen, en lees je meer over onderwerpen waar de faculteit zich mee bezighoudt.

Na de Academische Pabo kun je direct aan het werk in het basisonderwijs. Maar mocht je toe zijn aan meer verdieping, dan kun je ook nog een masteropleiding volgen.

Professor Edwin Bakker, directeur van het Centrum voor Terrorisme & Contraterrorisme heeft zijn nieuwe boek getiteld 'Terrorism and Counterterrorism Studies: Comparing Theory and Practice' bij Leiden University Press uitgebracht.

Promotores: J. Kok, M. Chaudron (Chalmers University)

Promotor: Prof.dr. E.F. Smets, Co-Promotor: L.W. Chatrou

The research described in this thesis centered on retaining exo-β-glucosidases implicated in health and disease, in particular the human inherited lysosomal storage disorder, Gaucher disease (GD).

De tweede, geactualiseerde druk van dit boek belicht de organisatie en het functioneren van de brandweer en brandweerzorg. In drie delen beschrijven wetenschappers en practitioners de turbulente ontwikkelingen van de afgelopen tien jaar, zoals de verbreding naar rampenbestrijding. Erwin Muller, hoogleraar…

Dit is een Virtual Reality onderzoek naar de veiligheid van woonwijken. Hiervoor hebben de afgelopen maanden 200 gedetineerden meegewerkt aan dit onderzoek en nu willen we graag ook 200 mensen uit de maatschappij uitnodigen mee te doen met dit onderzoek.

This dissertation combines the use of defined microenvironments, high-resolution fluorescence microscopy, and time-resolved analysis, to study intracellular and cellular motility.

Astronomical observations of cold regions in the universe show a rich inventory of ices. Part of these ices may end up on planets like our own, but in that journey they will be exposed to considerable amounts of radiation.

In this work, we investigate the minute circular dichroism effects of single nanoparticles.To this aim, we apply photothermal imaging with a polarization-modulated heating beam.

Het onderzoek van de Intelligence and Security Studies Group naar inlichtingen en veiligheid draagt bij aan academische kennis, voedt de publieke discussie, ondersteunt ons onderwijs en de ontwikkeling van professionele praktijk.

Ons onderwijsaanbod is breed en divers. Hieronder vindt u alle informatie over de vakken die door de afdeling Bedrijfswetenschappen worden verzorgd. Als u op een vak klikt, wordt u doorgeleid naar de studiegids.

Bereid je voor op de MSc Political Theory: Legitimacy and Justice aan Universiteit Leiden met oriëntatieactiviteiten, studiebronnen, visuminformatie, studentenondersteuning en praktische aankomsttips.

Ontdek hoe je je kunt voorbereiden op de masteropleiding The Politics of Artificial Intelligence aan de Universiteit Leiden: oriëntatieactiviteiten, academische bronnen, visumadvies en studentenondersteunende diensten.

Bereid je voor op de MSc Nationalism, Ethnic Conflict and Development aan Universiteit Leiden met oriëntatieprogramma’s, studiebronnen, visumondersteuning en studentenbegeleiding.

Promotor: Prof.dr. A.G.G.M. Tielens

The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.

In the current global context, there is a pressing need to address sustainable energy supplies to safeguard our Planet and its ecosystems. The choices made by human society have a significant impact on genetic evolution and climate.

Op 11 november 2021 verdedigde Evelien Campfens het proefschrift 'Cross-border Claims to Cultural Objects'. Het promotieonderzoek is begeleid door prof.dr. N.J. Schrijver en prof.dr. W.J. Veraart (VU Amsterdam).

This thesis investigates the application of deep learning techniques in image analysis across various domains, focusing on four main themes: feature extraction, classification, segmentation, and integration, demonstrating the transformative potential of these technologies.

De Engelstalige bacheloropleiding Urban Studies ging dit jaar van start, maar wat houdt de opleiding precies in? André Gerrits, hoogleraar International Studies and Global Politics, was te gast bij Sleutelstad om te spreken over deze nieuwe opleiding.

The Oxford Byzantine Graduate Seminar is designed to showcase the breadth of graduate research in modern Late Antique and Byzantine Studies and to foster academic collaboration across institutions and sub-disciplines.

The Oxford Byzantine Graduate Seminar is designed to showcase the breadth of graduate research in modern Late Antique and Byzantine Studies and to foster academic collaboration across institutions and sub-disciplines.

Pharmaceutical companies, governments and the general public have become increasingly aware that animal models used in drug testing lack vital aspects to serve as an accurate representation of human biology. As models of the human body should become more physiologically relevant, animal models no longer…

To meet the rising demand for minerals driven by the global shift to clean energy technologies, ensuring responsible and resilient supply chains is critical. Minerals like cobalt, lithium, and nickel for batteries, neodymium and zinc for wind turbines, and indium for solar panels are essential.

The main subject of this thesis is the design and synthesis of paramagnetic molecules for protein studies with NMR and EPR spectroscopy.

Promotor: Prof.dr. T. Schmidt, Co-Promotor: S.J.T. van Noort

Actinobacteria are Gram-positive bacteria that have a complex multicellular life cycle and are well known for their ability to produce a wide range of bioactive natural products (NPs).

Adenosine diphosphate ribosylation (ADP-ribosylation) is a fascinating post-translational modification (PTM) that plays a role in a variety of cellular processes and is associated with several diseases, including cancer and viral infections.

Empirisch en experimenteel onderzoek dat zich richt op literair, juridisch, medisch en audiovisueel vertalen.

In his dissertation Michiel Hooykaas outlines the results of six empirical research projects focused at biodiversity awareness in the Netherlands, specifically people’s knowledge about animals.

Binnen de afdeling Publiek Management en Organisatie van het Instituut Bestuurskunde houden wij ons bezig met publieke organisaties en met de manier waarop managers en professionals daarbinnen hun werk doen.

In design optimization problems, engineers typically handcraft design representations based on personal expertise, which leaves a fingerprint of the user experience in the optimization data. Thus, learning this notion of experience as transferrable design features has potential to improve the performance…

Carbohydrates, or sugars, are the most diverse and most abundant biomolecules known. However, the isolation of carbohydrate samples in sufficient amounts and purity is often impractical or even impossible, so the chemical synthesis of glycosides becomes relevant. The glycosylation reaction, in which…

The adsorption of D2 and CO2 on catalyst surfaces is studied using a molecular beam in ultra-high vacuum.

Promotor: Prof.dr. M. Ubbink, Co-promotor: G. Siegal

In this thesis, two potential therapeutic targets for diabetic nephropathy were dentified and investigated. First, we show that glomerular clusterin is upregulated in diabetic nephropathy and demonstrated that recombinant clusterin protein can protect the podocytes against oxidative stress in vitro.…

Promotor: Promotor: W.Th.F. den Hollander, Co-promotor: V. Sidoravicius.