De activiteit van het brein verandert naarmate mensen ouder worden, wat kan leiden tot cognitieve achteruitgang. Door hersendata van muizen en mensen te meten en vergelijken, wil de onderzoeker begrijpen hoe tijdens het ouder worden de ruizigheid van ons brein verandert en keuzegedrag beïnvloedt.

De volgende collega's maken deel uit van de Academia in Motion Regiegroep.

Hoe zetten we een permanent, facultaire-overstijgend netwerk op dat interdisciplinaire samenwerking tussen universitair docenten stimuleert?

Promotores: Prof.dr. E.A.L. Biessen, Prof.dr. T.J.C. van Berkel

Cardiovascular diseases are among the most frequent causes of death in the world. The main underlying pathology of cardiovascular diseases is the development of atherosclerosis in the medium and large-sized arteries.

In november 2020 is het Engelstalige boek ‘Financial Collateral; Law and Practice’ verschenen. Het boek is gepubliceerd door Oxford University Press en geredigeerd en geschreven door professor Matthias Haentjens. Voorts hebben meegeschreven Anthony Zacaroli (High Court, Chancery Division), Yael Diamant…

In this thesis, deep learning is studied from a statistical perspective. Convergence rates for the worst case risk bounds of neural network estimators are obtained in the classification, density estimation and linear regression model.

In this thesis, we study systems of electrons in which strong correlations give rise to emergent exotic physics.

Promotor: E.F. Smets, Co-promotor: J. Geml

The plant hormone auxin regulates plant growth and development through polar cell-to-cell transport-generated maxima and minima. PIN FORMED (PIN) auxin efflux carriers determine the direction of this auxin flow through their asymmetric placement on the plasma membrane (PM).

We developed the bitterling as a unique, well-studied model organism in the area of the evolutionary ecology of brood parasitism. The bitterling-mussel relationship, interspecific mussel host preference, and mussel gill structure are studied in detail, to help understand the developmental adaptation…

Promotor: Prof.dr. J.A. Bouwstra, Co-promotor: A. El Ghalbzouri

A new publication on changes in the relationship between news and their public in Chile

Mechanical metamaterials are carefully engineered materials whose properties are controlled by their structure, not by their composition, which allows using metamaterials to study and control physical effects in detail⁠.

Promotor: Prof. dr. Arnold Tukker & Prof. dr. René Kemp (Maastricht University)

Promotores: Wim Jiskoot; Ferry Ossendorp

Cardiovascular syndromes are the major cause of death in Western societies.

In light of climate change, it is crucial to determine whether plant species can adapt to future climates to avoid extinction. Plants adapt to various conditions by altering their functional traits, such as leaf size or photosynthetic rate. Some traits appear linked and vary together between species,…

Promotor: J.N. Kok, Co-promotor: M.S. Lew

Healthy aging is one of the prime goals in today's society and atherosclerosis is among the greatest causes of morbidity in elderly. Cardiovascular disease patients receiving treatment are often of advanced aged and have an aged immune system, which limits translating experimental findings to the pa…

Plant diversity is essential for us and our planet as it sustains the stability of our ecosystems, provides vital materials and food to us and supports many ecosystem services.

As a contribution to the changing legislation and evolving societal attitudes concerning environmental issues, this project aims to enhance and manipulate the plants’ own natural defense mechanisms against western flower thrips (WFT).

Promotor: W. Jiskoot, Co-promotor: A. Hawe

It is a common technique in global optimization with expensive black-box functions to learn a surrogate-model of the response function from past evaluations and use it to decide on the location of future evaluations.

Onderzoek van de sectie Methodologie & Statistiek van het Instituut Psychologie aan de Universiteit Leiden

This dissertation presents the synthesis and evaluation of antibody recognition for various capsular polysaccharide (CP) fragments of Staphylococcus aureus (S. aureus).

Kinase inhibitors are key therapeutic agents, particularly in oncology, yet their clinical efficacy is often hampered by off-target effects and limited understanding of their cellular target profiles.

Advanced UHF MRI techniques provide powerful tools for studying the zebrafish brain, an emerging model in neurological research. In this work, various MRI and localized MRS methods are optimized and employed for UHF strength for studying the zebrafish brain.

Promotor: J.A. van Veen, Co-promotor: E.E. Kuramae

Promotor: Prof.dr. M.L. van Hecke, Co-Promotor: V. Vitelli

Organisms often need to adapt more efficiently and devise new strategies for surviving difficult ecological circumstances.

Control of infectious diseases poses continuous challenges for human health.

Prof.dr. J. Memelink

The zebrafish is a promising vertebrate model organism in early drug discovery and development.

Promotores: Prof.dr. J. Kuiper, Prof.dr. P.H.A. Quax, Co-promotor: I. Bot

Invasive lobular carcinoma (ILC) is the second most common type of breast cancer.

Plant-microbe interaction resulted in different physio/chemical responses by host plant and interacting rhizobacteria.

Promotor: G.J. Kramer Co-Promotor: E.G.M. Kleijn

Promotor: Prof.dr. H.P. Spaink, Co-promotor: Dr. M. van der Zee

Traditionally, vaccines are administered intramuscularly using conventional hypodermic needles, which cause pain and distress. Microneedles are very short needles (smaller than 1 mm) that are practically invisible to the naked eye.

Promotores: J. Jonkers, K.E. de Visser

During embryonic growth, cells proliferate, differentiate, and collectively migrate to form different tissues at the right position and time in the body.

Promotores: Prof.dr. M. Danhof, Prof.dr. D.R. Stanski

During post-embryonic development into adults, animals face an environment that fluctuates constantly. For example, in nutrient availability, temperature, and osmolarity (e.g., salt concentration).

Promotor: Prof.dr. B. van de Water

Promotor: Johan Kuiper, Co-promotor: Saskia C.A. de Jager

Plants and their pollinators form complex interaction networks. Within these networks, species differ widely in the number of species they interact with.

By growing in a soil plants change the biotic and abiotic properties of the soil in which they grow.

Immunotherapies for cancer are an emerging class of therapeutic strategies which aim to treat cancer via augmentation of the immune system.