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2,635 zoekresultaten voor “state cell technology” in de Publieke website

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  Ferdinand Teichert Promovendus / gast

  Faculteit der Wiskunde en Natuurwetenschappen

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  Max Fernkorn Onderzoeker

  Faculteit der Wiskunde en Natuurwetenschappen

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  Micha Drukker Hoogleraar

  Faculteit der Wiskunde en Natuurwetenschappen

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  Ruben de Vries Promovendus

  Faculteit der Wiskunde en Natuurwetenschappen

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  Yuting Wang Promovendus

  Faculteit der Wiskunde en Natuurwetenschappen

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  Daan Vlemmings Analist

  Faculteit der Wiskunde en Natuurwetenschappen

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  Nina Schulten Onderzoeksanalist

  Faculteit der Wiskunde en Natuurwetenschappen

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  Christian Schröter Universitair docent

  Faculteit der Wiskunde en Natuurwetenschappen

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  Andreea Iosif Analist

  Faculteit der Wiskunde en Natuurwetenschappen

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  Cecile Herbermann Project analist

  Faculteit der Wiskunde en Natuurwetenschappen

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  Rafaella Buzatu Promovendus

  Faculteit der Wiskunde en Natuurwetenschappen

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  Joey Zuijdervelt Promovendus

  Faculteit der Wiskunde en Natuurwetenschappen

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  Eliane Züger Promovendus

  Faculteit der Wiskunde en Natuurwetenschappen

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  Jingchao Wu Onderzoeker

  Faculteit der Wiskunde en Natuurwetenschappen

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  Yubin Guo Promovendus / gast

  Faculteit der Wiskunde en Natuurwetenschappen

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  Benjamin Tak Promovendus

  Faculteit der Wiskunde en Natuurwetenschappen

• RNA splicing in breast cancer progression Onderzoeksoutput

  In this thesis, we aimed to better understand the underlying mechanisms involved in TNBC progression and metastasis formation and discover new targets to reduce breast cancer related deaths.

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  Paul van Trigt Universitair docent

  Faculteit der Geesteswetenschappen

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  Huub de Groot Emeritus hoogleraar

  Faculteit der Wiskunde en Natuurwetenschappen

• Regulation of actomyosin contraction as a driving force of invasive lobular breast cancer Onderzoeksoutput

  In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).

• Extracellular Matrix Mechanics in the Regulation of the early steps of the Metastatic Cascade Onderzoeksoutput

  Metastasis is responsible for over 90% of cancer-related deaths and arises from the ability of a small subset of tumor cells to detach from the primary tumor, overcome multiple biochemical and mechanical barriers, disseminate through the body, and colonize distant organs.

• Cristina del Real nam deel aan presentatie van Office of Science and Technology voor Spaanse regering Nieuws - 24 november 2022

  Cristina del Real, universitair docent Cyber Crisis bij het Institute Security and Global Affairs, nam deel aan de presentatie van het Office of Science and Technology (OficinaC) voor het Spaanse Congres van Afgevaardigden (het Spaanse parlement). Ze is een expert in cyber security, een van de vier…

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  Vincent Koeman Promovendus

  Faculteit der Wiskunde en Natuurwetenschappen

• On transport properties of Majorana fermions in superconductors: free & interacting Onderzoeksoutput

  Majorana fermions in superconductors are the subgap quasiparticle excitations that are their own antiparticles.

• Liberalisering en privatisering in het bestuursrecht bij de Raad van State Nieuws - 4 november 2016

  Vrijdag 28 oktober 2016 vond op de Raad van State het symposium ‘De gevolgen van privatisering en liberalisering voor de rechtsbescherming door de bestuursrechter’ plaats. De Afdeling Staats- en bestuursrecht van de Universiteit Leiden en de Raad van State organiseerden gezamenlijk dit symposium, ter…

• Raad van State zet streep door schietbanen Defensie Nieuws - 15 januari 2025

  De discussie over de sluiting van illegale schietbanen van Defensie, als gevolg van de stikstofwetgeving is ingewikkeld en omvat diverse juridische aspecten. Armin Cuyvers, hoogleraar Europeesrecht, bespreekt de zaak in BNR-Nieuwsradio.

• Summer Course: Europeanisation of Administrative Law in the Member States Nieuws - 15 juni 2017

  Van 26 t/m 30 juni 2017 organiseert de afdeling Staats- en Bestuursrecht van de Universiteit Leiden een zomercursus over de Europeanisering van het nationaal bestuursrecht in de lidstaten van de Europese Unie.

• Targeted Therapy for Triple-Negative Breast Cancer Onderzoeksoutput

  The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.

• Sensing Transport Onderzoeksoutput

  Solute carrier (SLC) transporters are a large and diverse class of relatively understudied transmembrane proteins.

• Physics implications of shape on biological function Onderzoeksoutput

  Shape and biological function are tightly connected. Physical descriptions are used to connect the shape of a biological system with its function.

• Flow and Vasculature in Organ-on-a-Chip systems Onderzoeksoutput

  Drug development critically depends on preclinical models that mimic human physiology, yet traditional two-dimensional cultures and animal models often lack predictive power.

• The heart of oxygenic photosynthesis illuminated Onderzoeksoutput

  Promotor: Prof.dr. H.J.M de Groot, Co-Promotor: A. Alia

• Systems microscopy to unravel cellular stress response signalling in drug induced liver injury Onderzoeksoutput

  Promotor: B. van de Water

• Orientational Order and Confinement in Biological Tissues Onderzoeksoutput

  This thesis investigates how cell shape and collective behavior influence the dynamics and structure of biological tissues, which are crucial for understanding processes like embryonic development, tissue regeneration, and metastasis.

• Growth-induced self-organization in bacterial colonies Onderzoeksoutput

  Mechanical forces are known to play an important role in bacterial colonies. In this dissertation, we study the self-organization at various stages of growing bacterial colonies, and focus on the mechanical effects of cell growth.

• Development of a healthy and diseased artery-on-a-chip Onderzoeksoutput

  Cardiovascular diseases are a leading cause of death worldwide, and better models are urgently needed for disease progression studies and drug development.

• High throughput microscopy of mechanism-based reporters in druginduced liver injury Onderzoeksoutput

  Promotor: B. van de Water

• Over het programma Regeneratieve geneeskunde: patiënten genezen door herstel van organen, weefsel en cellen

  In 2020 zijn de stimuleringsprogramma's van de Universiteit Leiden gestart, met als één van de programma's regeneratieve geneeskunde.

• Laboratory for Ceramics Studies Onderzoeksfaciliteit

• Software Onderzoeksfaciliteit

  Image-Pro Plus, ImageJ, Cell Profiler, R, Knime en NIS-elements

• Mutation-Driven Modulation of GPCR Pharmacology: Insights from Adenosine and Serotonin Receptors Onderzoeksoutput

  This thesis seeks to investigate how cancer-associated mutations affect the pharmacological properties of selected GPCRs—primarily A2AAR and 5-HT2CR—through a combination of ligand binding assays, signaling readouts, kinetic profiling, and cellular functional assays.

• Composition and function of integrin adhesions Onderzoeksoutput

  Integrins play an essential role in multicellular life by connecting cells to the extracellular matrix.

• Deep Learning Solutions for Domain-Specific Image Segmentation Onderzoeksoutput

  Image segmentation is a fundamental task in computer vision, with applications ranging from medical diagnostics to archaeological research.

• Spatio-temporal aspects of antigen cross-presentation in dendritic cells: with click-to-release chemistry Onderzoeksoutput

  The first steps are made in personalised cancer vaccination strategies, which aim to induce a more specific immune response with fewer side effects. The activation of cytotoxic T cells is crucial for an effective immune response.

• Analysis of sub-visible particles in complex injectable formulations Onderzoeksoutput

  Promotors: W. Jiskoot; G.J. Witkamp, Co-promotor: M.R. Nejadnik

• Metabolomics study of blood vessels-on-chip model Onderzoeksoutput

  Endothelial dysfunction and microvascular diseases are key drivers of cardiovascular disease, the world's leading cause of death.

• More is alive: emergent multi-scale order & collective flows in tissues Onderzoeksoutput

  The overarching goal of this thesis is to set the foundations, but also make the first essential steps towards establishing a comprehensive, mesoscopic, hydrodynamic theory of epithelial tissues. The stage is set by an exhaustive study of topological defects in passive p-atic liquid crystals, singularities…

• The physics of nanowire superconducting single-photon detectors Onderzoeksoutput

  Promotores: Prof.dr. D. Bouwmeester, Prof.dr. A. Fiore (TU Eindhoven)

• Dynamics of TNFalpha signaling and drug-related toxicity Onderzoeksoutput

  In previous studies at our laboratory it was demonstrated that drug exposure of HepG2 cells can lead to an altered TNFα-induced NF-κB oscillatory phenotype, concurrent with a synergistically increased sensitivity for TNFα-induced apoptosis.

• Mechano-transduction mediated by integrin-based adhesion complexes: integration of cytoskeleton and adhesion dynamics Onderzoeksoutput

  In this thesis, we focus on novel proteins/mechanisms that regulate integrin-adhesion mediated mechano-transduction.