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1,654 zoekresultaten voor “strw cell differentiatie” in de Publieke website

• Nanofluidic tools for bioanalysis : the large advantages of the nano-scale Onderzoeksoutput

  Promotor: Prof.dr. T. Hankemeier, Prof.dr. J.C.T. Eijkel (Twente University)

• Immunity in atherosclerosis: novel assays, biomarkers and therapeutic approaches Onderzoeksoutput

  Atherosclerosis is a progressive disease resulting in the formation of an arterial plaque. Despite lipid lowering, recurrent cardiovascular events remain a risk. While atherosclerosis is primarily lipid-driven, the immune system plays a critical role in the pathophysiology.

• Mitochondria in chemical-induced toxicity Onderzoeksoutput

  Chemical-induced organ toxicity is a major concern in the development and use of chemicals, including drugs, pesticides, industrial chemicals and cosmetics. In the last decades, the onset and progression of chemical-induced organ toxicity has been linked amongst others to perturbation of mitochondri…

• Design, synthesis and application of paramagnetic probes for protein structure studies Onderzoeksoutput

  The main subject of this thesis is the design and synthesis of paramagnetic molecules for protein studies with NMR and EPR spectroscopy.

• Systems vaccinology: molecular signatures of immunity to Bordetella pertussis Onderzoeksoutput

  Promotor: G.F.A. Kersten, W. Jiskoot, Co-promotor: B. Metz

• Carcinogenicity of insulin analogues Onderzoeksoutput

  Promotor: Prof.dr. B. van de Water

• Evaluation of the zebrafish embryo as an alternative model for hepatotoxicity testing Onderzoeksoutput

  Promotor: Prof.dr. B. van de Water, Co-promotores: L.T.M. van der Ven, A.S. Kienhuis

• The advantages and disadvantages of bioorthogonal proteins Onderzoeksoutput

  This thesis describes the use of bioorthogonal proteins in immunological settings. It provides an introduction towards the field of protein modification, which was used throughout the thesis for the expression of proteins containing unnatural amino acids.

• The ecological relevance of chemical diversity in plants Onderzoeksoutput

  Promotor: P.G.L. Klinkhamer, Co-Promotores: K. Vrieling, P.P.J. Mulder

• Functional analysis of agrobacterium tumefaciens virulence protein VirD5 Onderzoeksoutput

  Supervisor: P.J.J. Hooykaas

• Surviving embryogenesis: The extraembryonic serosa protects the insect egg against desiccation and infection Onderzoeksoutput

  Promotor: Prof.dr. H.P. Spaink, Co-promotor: Dr. M. van der Zee

• Cholesterol metabolism and hematopoiesis interaction in atherothrombosis Onderzoeksoutput

  Cardiovascular disease is the leading cause of death worldwide.

• Modulation of leukocyte homeostasis in atherosclerosis Onderzoeksoutput

  Promotores: Prof.dr. E.A.L. Biessen, Prof.dr. T.J.C. van Berkel

• The interplay between lipids and the immune system in atherosclerosis Onderzoeksoutput

  Cardiovascular diseases are among the most frequent causes of death in the world. The main underlying pathology of cardiovascular diseases is the development of atherosclerosis in the medium and large-sized arteries.

• The good? The bad? The mutant! Characterization of cancer-related somatic mutations and identification of a selectivity hotspot in adenosine Onderzoeksoutput

  G protein-coupled receptors (GPCRs), one of the largest families of membrane proteins, are responsive to a diverse set of physiological endogenous ligands including hormones and neurotransmitters.

• Resistance to PARP inhibition by DNA damage response alterations in BRCA1/2-deficient tumors Onderzoeksoutput

  Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.

• Controlling growth and morphogenesis of the industrial enzyme producer Streptomyces lividans Onderzoeksoutput

  Promotor: G.P. van Wezel, Co-Promotor: E. Vijgenboom

• Development of a Kidney-on-a-Chip Model for Compound Screening and Transport Studies Onderzoeksoutput

  Pharmaceutical companies, governments and the general public have become increasingly aware that animal models used in drug testing lack vital aspects to serve as an accurate representation of human biology. As models of the human body should become more physiologically relevant, animal models no longer…

• Advances in GPCR Modeling Evaluated by the GPCR Dock 2013 Assessment: Meeting New Challenges Onderzoeksoutput

  Source: Structure , Volume 22, Issue 8, pp. 1120-1139 (2014)

• Vaccination and Targeted Therapy Using Liposomes; Opportunities for Treatment of Atherosclerosis and Cancer Onderzoeksoutput

  This thesis focuses on using liposomes in two different treatment strategies; vaccination (or immunotherapy) and delivery of a small molecule, and in two different disease models; cancer and atherosclerosis.

• The architects of crenarchaeal chromatin: A biophysical characterization of chromatin proteins from Sulfolobus solfataricus Onderzoeksoutput

  Promotor: Jaap Brouwer, Co-promotor: Remus Th. Dame

• Disrupting the transcriptional machinery to combat triple-negative breast cancer Onderzoeksoutput

  Triple-negative breast cancer (TNBC) is a subtype of breast cancer characterized by limited treatment options and unfavorable clinical outcomes. Therefore, the research described in this thesis focused on the exploration of novel targeted therapies for TNBC.

• Platinum electrochemistry through a magnifying glass Onderzoeksoutput

  In most applications, electrocatalysts exhibit a large surface area to volume ratio, for example using nanoparticles.

• Exploring novel regulators and enzymes in salicylic acid-mediated plant defense Onderzoeksoutput

  Salicylic acid (SA) is a plant hormone, which is involved in the defense responses to pathogens and to abiotic stress, and in the regulation of plant growth and development.

• Gevolgen van pesticiden in natuur volop in het nieuws Nieuws - 12 december 2025

  Veel media besteden aandacht aan de gevolgen van pesticiden in de natuur. Onder andere in Trouw vertelt hoogleraar Martina Vijver dat niet alleen pesticiden die boeren gebruiken, maar ook schoonmaakmiddelen en muggenspray een groot effect op leven in het water. 'Als schadelijke stoffen in het water…

• Some Assembly Required: The Structural Evolution and Mass Assembly of Galaxies at z Onderzoeksoutput

  This thesis investigates the structural evolution and assembly of galaxies since the first few billions years after the big bang.

• Unveiling the nature of giant radio galaxies Onderzoeksoutput

  The thesis deals with the study of giant radio galaxies (GRGs), which are radio galaxies of megaparsec sizes.

• Imaging polarimetry for the characterisation of exoplanets and protoplanetary discs. Scientific and technical challenges Onderzoeksoutput

  Promotor: Prof.dr. C.U. Keller

• Spectropolarimetry for planetary exploration Onderzoeksoutput

  Promotor: Prof.dr. C.U. Keller, Co-promotor: Frans Snik

• Time Domain Imaging of Transient and Variable Radio Sources Onderzoeksoutput

  This thesis focuses on the study of transient and variable radio sources in the universe.

• Metals in the diffuse gas around high-redshift galaxies Onderzoeksoutput

  Promotores: Prof.dr. J. Schaye & Prof.dr. C. Steidel (California Institute of Technology)

• Accessible remote sensing of water Onderzoeksoutput

  Water is all around us and is vital for all aspects of life. Studying the various compounds and life forms that inhabit natural waters lets us better understand the world around us.

• Non-linear astrochemical kinetics: theory and applications Onderzoeksoutput

  This Thesis shows discoveries in non-linear astrochemical kinetics as well as a deeper analysis of dark clouds chemistry.

• Galaxy formation and the structure of the Universe Onderzoeksoutput

  Promotores: Prof.dr. J. Schaye, Prof.dr. S.D.M. White (MPA Garching)

• Turtles all the way down: multiscale simulations connecting star and planet formation Onderzoeksoutput

  The formation of stars and planets happens over multiple scales, which can interact. In particular, planet formation happens in the dense, complex environment of star forming regions.

• The Sky is Made of Lava: How lava worlds reveal their interiors through their atmospheres Onderzoeksoutput

  Hot rocky exoplanets are planets that orbit so close to their host star that they possess a molten surface.

• Contact Vereniging van Oud-Sterrewachters

  Mail ons met vragen of opmerkingen op VO-S@strw.leidenuniv.nl

• Tracing the evolution of protoplanetary disks Onderzoeksoutput

  Promotores: Prof.dr. A.G.G.M. Tielens, Prof.dr. L.B.F.M. Waters (UvA), Prof.dr. C. Dominik (UvA)

• Causing a stir: Radiative and mechanical feedback in starburst galaxies Onderzoeksoutput

  Promotores: Prof.dr. F.P. Israel, Prof.dr. P.P. van der Werf

• Search for cosmic neutrinos with ANTARES Onderzoeksoutput

  Promotor: Prof.dr. M. de Jong, Co-Promotor: A.J. Heijboer

• A molecular journey : tales of sublimating ices from hot cores to comets Onderzoeksoutput

  The thesis explores how interstellar chemistry evolves as a function of time and changing physical architectures during the formation of stars.

• UV Photodesorption and Photoconversion of Interstellar Ices Onderzoeksoutput

  This thesis is an experimental study of the UV irradiation of the interstellar ice analogues, relevant for the different stages of the star and planet formation sequence.

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  Cecile Herbermann Project analist

  Wiskunde en Natuurwetenschappen

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  Micha Drukker Hoogleraar Stem Cell Technology for Microphysiological Modeling

  Wiskunde en Natuurwetenschappen

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  Nina Schulten Onderzoeksanalist

  Wiskunde en Natuurwetenschappen

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  Ferdinand Teichert Promovendus / gast

  Wiskunde en Natuurwetenschappen

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  Benjamin Tak Promovendus

  Wiskunde en Natuurwetenschappen

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  Max Fernkorn Onderzoeker

  Wiskunde en Natuurwetenschappen

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  Rafaella Buzatu Promovendus

  Wiskunde en Natuurwetenschappen

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  Yuting Wang Promovendus

  Wiskunde en Natuurwetenschappen