Hoe kan de geschiedenis worden achterhaald uit een ongedateerde mythologische tekst van een onbekend auteur? Op deze vraag zal prof.dr. Peter Bisschop aanstaande vrijdag ingaan tijdens zijn oratie getiteld

Jim Been, Universitair Docent bij de Afdeling Economie, heeft 28 januari jongstleden de Netspar Ph.D. Thesis Award in ontvangst mogen nemen voor zijn proefschrift getiteld “Pensions, Retirement, and the Financial Position of the Elderly”.

This thesis is concerned with the constitution of chiral responsive matrix assemblies that may undergo light-driven conformational changes and self-select vibrations to develop vibronic states for driving semi-classical coherent transfer with nearly 100% yield in a lossless NCAP process.

Our recent excavations have focused on the more recent New Kingdom/Late Period (ca. 1500-332 BCE) material.

What is leadership? Can it be taught, and if so, how? The International Leiden Leadership Programme (ILLP) helps students find their own style, say ILLP graduate Marko Simovski and his former coach Annah Neve in an interview: 'It’s about you, discovering you.'

Na het afronden van de bacheloropleiding volgen verreweg de meeste studenten een masteropleiding zoals Bio-Pharmaceutical Sciences, maar ook andere masters behoren tot de mogelijkheid. Voor een selecte groep afgestudeerde BFW-ers is doorstromen naar de masteropleiding Farmacie in Leiden mogelijk.

Reinforcement learning is a framework that enables agents to learn in a manner similar to humans, i.e. through trial and error. Ideally, we would like to train a generalist agent capable of performing multiple tasks and achieving various goals.

Promotor: Prof.dr. H.V.J. Linnartz

In Nederland doet het CDA onder eigen naam mee bij de aankomende waterschapsverkiezingen,maar in Limburg dient de partij al vijftien jaar geen kieslijsten in en worden de belangen behartigd door negen lokale partijen. Dit om zoveel mogelijk invloed uit te kunnen oefenen bij regionale problemen, zoals…

Promotor: Prof.dr. M. de Jong

Carbohydrates are present on the surface of bacteria making them suitable antigen candidates for vaccine development. This thesis deals with the synthesis of two carbohydrate-based components; the capsular polisaccharide of S. aureus type 5 and teichoic acids from staphilococci and enterococci speci…

This work has described synthetic strategies towards well-defined structures resembling capsular polysaccharide (CPS) fragments, CPS mimics, teichoic acid (TA) fragments as well as a third-generation ring-closing tandem metathesis (RCM) linker to better exploit the potential of automated synthesis.

Volg de stapsgewijze aanmeldprocedure voor de MSc Nederlandse Politiek aan Universiteit Leiden: begin in Studielink, vervolg via uSis, dien je toelatingsverzoek in en registreer je na toelating.

Lees hoe je je aanmeldt voor de MSc International Organisation aan Universiteit Leiden – inclusief stappen via Studielink, documenten indienen en vervolgstappen.

Promotor: Carel J. ten Cate, Co-Promotor: Hans W. Slabbekoorn

In this thesis, we use low-frequency and high-frequency radio observations to address the following questions regarding quasars: is the radio loud/quiet quasar dichotomy real?

It is a common technique in global optimization with expensive black-box functions to learn a surrogate-model of the response function from past evaluations and use it to decide on the location of future evaluations.

Promotor: J. N. Kok, Co-promotor: A. J. Knobbe

Optimization tasks in practice have multifaceted challenges as they are often black box, subject to multiple equality and inequality constraints and expensive to evaluate.

Time-series forecasting through modelling sequences of temporally dependent observations has many industrial and scientific applications. While machine learning models have been widely used to create time-series forecasting models, creating efficient and performant time-series forecasting models is…

Promotor: Prof.dr.ir. E. Deprettere

Promotor: Prof.dr. J.N. Kok, Co-promotor: A.J. Knobbe

The aim of this thesis is to expedite and ensure the systematic accuracy of clearance scaling from adults to paediatric patients, with a special focus on drugs undergoing hepatic metabolism.

Promotores: T.H. Oosterkamp, N. de Jonge

Acute cardiovascular syndromes, including myocardial infarction or stroke, are the principal cause of death in the Western society. The main underlying pathology of cardiovascular diseases is atherosclerosis, which is caused by the accumulation of lipids and inflammatory cells in the vessel wall, in…

This thesis presents the first synthetic peptides ADP-ribosylated on serine, threonine, tyrosine, arginine and cysteine.

CrO2, a half-metal ferromagnet, has shown great promise for superconducting spintronics applications for nearly two decades.

Nicotinamide adenine dinucleotide (NAD+) is the substrate used for the introduction of the ubiquitous and highly dynamic PTM in which either one or multiple adenosine diphosphate ribose (ADPr) moieties are covalently attached to a nucleophilic side chain of an specific amino acid in the target protein…

Increasing the efficiency of gene targeting (GT) as a genome editing tool in plants has been an important goal in plant biotechnology.

Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa

Promotor: Prof.dr. E. Deprettere

Publicaties die verschijnen in het kader van het onderzoeksproject Zelfredzaamheid en sociale bescherming over de levenscyclus.

Food security is challenged by a growing global population and by climate change. Drought and soil salinity are considered the most important ones that inhibit crop yield and distribution. Worryingly, climate change is predicted to increase not only their frequency and severity, but also their co-occurrence,…

The main goal of this thesis is to achieve advanced control of binding properties in bis-pyrrolic and macrocyclic pyrrolic receptors by light.

Het Dual PhD Centre bestaat om een bijzondere groep promovendi aan de Universiteit Leiden extra ondersteuning te bieden: de duale promovendi.

Promotores: Prof.dr. P.C.W. Hogendoorn & Prof.dr. H.P. Spaink Co-promotor: Dr. B.E. Snaar-Jagalska

GLOBOX is a spatially differentiated multimedia fate, exposure and effect model. It is used for the calculation of spatially differentiated LCA characterisation factors on a global scale.

This dissertation explores how we can make anomaly detection—identifying unusual or faulty behavior in complex systems—more trustworthy and effective, with a focus on smart manufacturing.

Large parts of the research described in this Thesis aims at the development of oligopeptide-masked toxins and their in situ immunoproteasome-mediated activation.

In design optimization problems, engineers typically handcraft design representations based on personal expertise, which leaves a fingerprint of the user experience in the optimization data. Thus, learning this notion of experience as transferrable design features has potential to improve the performance…

Op 10 november 2021 verdedigde Carmel van Niekerk-Jacobs het proefschrift 'Realising the right to reproduce with assistance in South Africa'. Het promotieonderzoek is begeleid door prof.dr. J.J. Sloth-Nielsen en prof.dr. T. Liefaard.

This project uses archaeological, literary and epigraphic evidence to investigate urban development in Roman-period North Africa, compiling this in a GIS-linked database in order to analyse the development of urban settlement spatially over time.

The research described in this thesis centered on retaining exo-β-glucosidases implicated in health and disease, in particular the human inherited lysosomal storage disorder, Gaucher disease (GD).

International trade has played a major role in defining the modern global economy. Trade, however, entangles the environmental pressures of economic sectors, giving the illusion of environmental improvements, while the opposite may be occurring.

This ecological community has long been known to affect host biology, and their diverse roles have been further clarified in recent years following numerous studies of animal:microbiota interactions in diverse systems.