Bikes are one of the most sustainable ways of travel which use should be promoted by the University.

How do protein modifications work together to repair DNA, and what can we learn about these interactions to better understand disease?

The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.

What is the most effective way to eliminate tumour cells? The DNA repair mechanism could play an important role in increasing the effectiveness of chemotherapy in the fight against cancerous cells. If we are to influence this mechanism, we need fundamental knowledge about how the mechanism works.

The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.

In the studies described in this study, we introduce a novel ex vivo human skin barrier repair model. To develop this, we removed the upper layer of the skin, the stratum corneum (SC) by a reproducible cyanoacrylate stripping technique.

Searching for ways to delay the need for a transplant and trying to build kidneys to order.

The research presented in this thesis explores the chemotherapeutic potential of metal-based compounds as chemotherapy agents, with an initial focus on the synthesis and DNA interaction studies of platinum and palladium compounds utilizing the [Pt(bapbpy)]2+ scaffold. The study identifies intercalation…

What role do parent-child interactions play in the development, maintenance and treatment of depression in young people?

Atopic eczema is a skin disease with increasing incidence currently affecting 25% of the paediatric population. In atopic eczema the skin barrier function is reduced. This barrier is formed by the outermost layer of the skin called the stratum corneum (SC). The SC consists of terminally differentiated…

What is the relation between the experience and the act of exclusion?

The consequences of social tendencies for the legislation and institutions in the fields of social security, the labor market policy and pension reform are examined in this multdisciplinary research program..

Why does social anxiety increase in adolescence and how does it grow out of control in some adolescents?

This project aims at studying the social media reception of African publications as covered by the most important “altmetric” sources.

This dissertation takes an important step in understanding the phenomenon of non-take-up of social support and what it means for contemporary social policies.

Why do some children confront social challenges with confidence, whereas others experience difficulties? What is the role of child temperament and child emotional dispositions? What is the role of parenting? This project aims to shed light on the mechanisms explaining shyness and confidence in response…

Understanding DNA repair mechanisms is essential for advancing plant biotechnology and crop improvement. This study investigates how double-strand breaks (DSBs), induced by CRISPR/Cas systems, are repaired in the model plant Arabidopsis thaliana, and how these processes influence Agrobacterium tumefaciens…

Are there any differences in gaze behavior between high and low socially anxious individuals? What factors influence the relation between social anxiety and gaze behavior?

A neurobiological perspective on individual differences in social competence

Promotor: P. J. J. Hooykaas Co-promotor: B. S de Pater

The studies outlined in this volume explore how connectedness continues to change Africa and how Africa continues to shape the social life of connections.

The key subject of the Team Economic and Social History is Inequality (at local, national and global levels). We study this from an intersectional perspective: gender, class, ethnicity or race, religion, sexuality, age, ability/disability, citizenship and legal status. We study these categories of power…

Do you have to be able to say everything on Twitter and Facebook? Is Instagram morally obliged to remove photos from attacks? Should we allow the terrorist group to recruit new members on the internet?

This project investigates how people choose linguistic forms like questions or statements in everyday speech.

At the Young Academy Leiden, we care deeply about fostering social safety at our university. Increasing social safety is of particular importance to early career scholars as they often find themselves in a vulnerable position without a permanent contract, or with a dependence on superiors for progressing…

Helping people, groups and policymakers navigate the social transitions of our time.

In this article, the authors explore how international criminal law is moving into a ‘post-critical’ phase and examine its potential for emancipatory reform.

Increasing the efficiency of gene targeting (GT) as a genome editing tool in plants has been an important goal in plant biotechnology.

At FGGA, we want our staff to feel safe in all respects. We therefore strive to create a work environment where we treat each other with respect, where we promote inclusion and where we speak up if we experience or witness unsafety.

Agora, Wassenaarseweg 52, 2333 AK, Leiden

Efficiently responding to others’ emotions has great survival value, especially for social species, such as primates, who establish close, long-term bonds with group members. The closest living relatives to humans are the chimpanzee and the bonobo. Studying these species, and comparing them on the exact…

Social anxiety runs in families, but the neurobiology underlying this genetic vulnerability is until now largely unknown. The unique Leiden Family Lab study on Social Anxiety Disorder (LFLSAD) aims to broaden our knowledge with respect to this genetic susceptibility.

The [A]Social Creatures Lab is an interdisciplinary research lab that focuses on understanding social interaction with and between artificial creatures. Researchers and students from the Creative Intelligence & Technology group collaborate in it.

The SSH Sector Plans are a national initiative in which Dutch universities collaborate to strengthen research and education in the social sciences and humanities.

There are several ways to stay up to date via social media.

Social anxiety disorder is one of the most common disorders in children and young people. Social anxiety is characterized by excessive fear and avoidance of social situations. The primary fear in children with social anxiety is that they will be negatively judged by others. To date, the most frequently…

Innovation plays an essential role in firms' competitiveness and long-term success. It varies from different types, ranging from run-of-the-mill innovation that brings incremental changes to existing technologies to radical innovation that breaks from existing trajectories.

Social Citizenship & Migration (SCM) is one of the nine interdisciplinary programmes launched by Leiden University in 2020. It is led by the Faculties of Governance and Global Affairs, Law, Humanities, and Social Science.

This focus area adresses the social context of health and well-being, with a particular emphasis on social inequality.

Serious forms of anxiety concerning other people’s opinions can hinder teenagers at school in social interactions or carrying out tasks. Psychologist Anne Miers is looking for ways to reduce this so-called ‘social anxiety’.

The [a]social creatures lab focusses on understanding social interaction with and between artificial creatures.

At Leiden University’s Faculty of Social and Behavioural Sciences we keep in touch with our alumni in various ways.

Current social norms are unsustainable, making behavior change crucial for addressing the climate crisis. Social norms can shift rapidly after tipping points, but these are often only recognised in hindsight. To promote change, we need better predictive power, i.e. ability to detect early warning signs…

Explore how stakeholders in Gabon's Makokou region interact with forest resources in logging, agriculture, and mining, and their impacts on social and environmental changes.

This interdisciplinary research project explores several adaptive machine learning methods which can give insight into the interaction between human and machine. The ultimate goal is open and natural communication between humans and AI that should result in mutual trust, cooperation and coordination…