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1,105 search results for “bart cancer” in the Public website

• Exploring Grainyhead-like 2 target genes in breast cancer Research output

  The objective of this study was to investigate the expression and function of GRHL2 in different breast cancer subtypes.

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  Bart Bulsing Technical Information Manager / Draftsman

  Service Unit Real Estate

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  Bart Gorissen Lecturer

  Faculty of Law

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  Bart Wentholt Participating Coordinator MDA Open Access

  Leiden University Libraries

• RNA splicing in breast cancer progression Research output

  In this thesis, we aimed to better understand the underlying mechanisms involved in TNBC progression and metastasis formation and discover new targets to reduce breast cancer related deaths.

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  Bart Gorissen Lecturer

  Faculteit der Rechtsgeleerdheid

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  Bart Alewijnse Programmer/lab technician

  Faculty of Humanities

• Novel regulators of prostate cancer stem cells and tumor aggressiveness Research output

  Promotor: R.C.M. Pelger Co-Promotor: G. van der Pluijm

• Cancer and heredity Research Dossier: Cancer pathogenesis and therapy

  Some people are predisposed to develop cancer. Mutations in genetic material that increase a person’s chances of developing cancer can already be present at birth. Researchers are closely examining these mutations to learn more about how cancer begins to develop.

• Cancer pathogenesis and therapy Research Dossier

  With cancer, a person’s body cells grow uncontrollably. Putting together a detailed picture of how this comes about makes it possible to develop efficient therapies. Researchers at the Leiden University Medical Centre (LUMC) and Leiden University are working together to gain a better understanding…

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  Bart Lenselink Guest Scientist

• BRCA1-associated breast cancer: finding new weapons for an old villain Research output

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• Cancer Drug Target Discovery Research project

  We focus on a better understanding of the mechanisms of cancer drug resistance and metastasis.

• Cancer Pathogenesis and Therapy Research project

  Cancer represents a formidable current and future global health challenge. The LUMC medical research profile Cancer Pathogenesis and Therapy charges this challenge by developing and implementing innovative patient-tailored, multimodal diagnostic methods and treatment modalities.

• Cancer Drug Target Discovery

  In this research group, headed by Prof. Erik Danen, the aim is to unravel cellular signaling mechanisms in normal and diseased cells, with a long-standing interest in cell adhesion signaling. In complex multicellular organisms such as ourselves, a division of labor emerges where different tissues and…

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  Bart Schreuders Researcher/lecturer

  Faculteit der Rechtsgeleerdheid

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  Bart Roep Professor

• 
  Bart van Hoek Professor emeritus

• Identification of novel targets in prostate cancer progression Research output

  Promotor: Prof.dr. B. van de Water, Co-promotor: E.H.J. Danen

• Discovery of BUB1 kinase inhibitors for the treatment of cancer Research output

  The spindle-assembly checkpoint (SAC) is a safety mechanism which secures accurate chromosome segregation during mitosis.

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  Bart van der Hoogt Trainee

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  Bart de Vries Guest

  Faculty of Social and Behavioural Sciences

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  Bart Joosen Guest lecturer

  Faculteit der Rechtsgeleerdheid

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  Bart Collard External PhD candidate

  Faculteit der Rechtsgeleerdheid

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  Bart Schermer Professor

  Faculteit der Rechtsgeleerdheid

• Cancer Therapeutics and Drug Safety Cell Systems and Drug Safety

  In this research group, headed by Bob Van de Water, cell signaling programs that underlie adverse drug reactions as well as cancer development and progression are unraveled. Adverse drug reactions involve cell injury in critical target organ cells which leads to the activation of cellular stress response…

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  Bart Krans Professor of Private Law and Civil Procedure

  Faculteit der Rechtsgeleerdheid

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  Bart Custers Professor of Law and Data Science

  Faculteit der Rechtsgeleerdheid

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  Bart Schuurman Professor

  Faculteit Governance and Global Affairs

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  Bart Verheijen Assistant professor

  Faculty of Humanities

• Cancer chess: molecular insights into PARP inhibitor resistance Research output

  The clinical potential of applying synthetic lethality to cancer treatment is famously demonstrated by the BRCA1/PARP1 paradigm: a tumor specific defect in BRCA1 – a component of the DNA double-strand break (DSB) repair pathway homologous recombination (HR) – results in a remarkable sensitivity to PARP1…

• Unravelling cancer drug resistance mechanisms Research project

  Mechanisms fro drug resistance

• multifaceted roles of Grainyhead-like transcription factor-2 in breast cancer Research output

  Breast cancer is the most common cancer in women worldwide. Metastasis, the process by which cancer cells spread to other parts of the body, makes treatments less effective. It is important to unravel the mechanism of metastasis.

• Patient-derived models of breast cancer: a breakthrough story of the duct Research output

  To improve treatment of breast cancer patients it is important to understand all stages of breast cancer from initiation to in situ disease and progression to invasive disease. In this thesis we use intraductal injections of patient derived tissue to model ductal carcinoma in situ and invasive breast…

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  Bart Barendregt Dean/professor

  Faculty of Social and Behavioural Sciences

• PI3K signaling and adherens junctions in invasive lobular breast cancer Research output

  Invasive lobular carcinoma (ILC) is the second most common type of breast cancer.

• Cancer cells: A closer look Research Dossier: Cancer pathogenesis and therapy

  What distinguishes a tumour cell from a healthy cell? Researchers are trying to answer this question as precisely as possible. Certain differences could eventually lead to new therapies.

• Blueprints of Disease: Precision Platforms for Modelling Breast Cancer Research output

  Breast cancer (BC) is a clinically and biologically heterogeneous disease.

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  Bart de Leeuw Student Assistent

  Faculty of Humanities

• Pulling the strings on anti-cancer immunity Research output

  Promotores: J. Jonkers, K.E. de Visser

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  Bart van der Wal Professor

• Classical conditioning to improve immunotherapy in cancer Research project

  Can the conditioning paradigm be used for checkpoint inhibition cancer treatment?

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  Bart van Lieshout PhD candidate

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  Bart de Smit Vice Dean / professor

• Modeling and Targeting Tissue Dynamics in Fibrosis and Cancer Research output

  Drug development is hampered by the limited predictive value of conventional 2D culture systems, which fail to recapitulate the complexity of the disease microenvironment and contribute to high clinical attrition rates.

• Precision modeling of breast cancer in the CRISPR era Research output

  The molecular mechanisms that instigate a healthy cell to become malignant are fueled by (epi)genetic alterations in so-called driver genes.

• Image-based phenotypic screening for breast cancer metastasis drug target discovery Research output

  The main aim of this thesis was to unravel the signaling and regulatory networks that drive tumor cell migration during breast cancer metastasis.

• Pursuing new anti-cancer therapy as a team Leiden Early Drug Discovery & Development

  Cancer is the leading cause of death in the Netherlands, and, with over 100 different types of cancer, it’s not a simple disease. Today, skin, breast, lung, prostate and colon cancer are the most diagnosed forms. Therefore, the discovery and development of new drugs has the ability to significantly…

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  Bart van der Steen Head Faculty Liaison & Services

  Leiden University Libraries

• Liposome-based synthetic long peptide vaccines for cancer immunotherapy Research output

  Promotores: Wim Jiskoot; Ferry Ossendorp