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1,005 search results for “smit barrier re-pair” in the Public website

• Lipids as therapeutic targets for barrier repair in skin diseases Research output

  The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.

• A novel formulation for skin barrier repair : from ex vivo assessment towards clinical studies Research output

  The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.

• An ex vivo human skin model for studying skin barrier repair Research output

  In the studies described in this study, we introduce a novel ex vivo human skin barrier repair model. To develop this, we removed the upper layer of the skin, the stratum corneum (SC) by a reproducible cyanoacrylate stripping technique.

• A novel biofilm for skin barrier repair of patients with atopic eczema Research project

  Atopic eczema is a skin disease with increasing incidence currently affecting 25% of the paediatric population. In atopic eczema the skin barrier function is reduced. This barrier is formed by the outermost layer of the skin called the stratum corneum (SC). The SC consists of terminally differentiated…

• Skin Barrier and Vaccination

  The Skin Barrier and Vaccination group is led by Prof. Joke Bouwstra. One of the key functions of the skin is its barrier function, which is located in the uppermost layer of the skin, the stratum corneum. The stratum corneum consists of enucleated dead cells (corneocytes) embedded in a lipid matrix.…

• Green Bikes & Repair Points Leiden University Green Office

  Bikes are one of the most sustainable ways of travel which use should be promoted by the University.

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  Wanda Smit Management assistant

  Administration and Central Services

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  Johan Smit Operational technician

  Universitair Facilitair Bedrijf

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  Maartje Smit

  Social & Behavioural Sciences

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  Ashley Smit Guest employee

  Social & Behavioural Sciences

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  Robert Smit Postdoc

  Faculty of Science

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  Elisa Smit Communications Officer

  Student and Educational Affairs (SEA)

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  Flora Smit PhD candidate

  Faculty of Humanities

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  Egbert Smit Professor Pulmonology, in particular pulmonary oncology

  Faculteit Geneeskunde

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  Hemmo Smit Lecturer

  Social & Behavioural Sciences

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  Johannes Smit Professor Internal Medicine, in particular clinical endocrinology

  Faculteit Geneeskunde

• Impaired barrier of inflammatory skin diseases Research project

  Focus in skin research

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  Dana Smit Lecturer

  Social & Behavioural Sciences

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  Diederik Smit Assistant professor

  Faculty of Humanities

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  Michiel Smit PhD candidate

  Faculty of Law

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  Vincentius Smit Professor Clinical Pathology

  Faculteit Geneeskunde

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  Jorrit Smit Visiting researcher

  Social & Behavioural Sciences

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  Ben Smit Researcher

  ICLON

• Development of human skin equivalents to unravel the impaired skin barrier in atopic dermatitis skin Research output

  Promotor: J.A. Bouwstra Co-promotor: A. El Ghalbzouri

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  Sander van der Smit Privacy Officer

  Administration and Central Services

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  Corné Smit External PhD candidate

  Faculty of Law

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  Robert Smits Staff Member Reception

  Universitair Facilitair Bedrijf

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  Tirza Smits Blended Learning officer

  Social & Behavioural Sciences

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  Sharon Smits Student counsellor

  Student and Educational Affairs (SEA)

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  Monica Smits Senior Staff Member Communication

  ISSC

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  Monique Smits Library staff member

  Leiden University Library

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  Ileen Smits Project manager

  Administration and Central Services

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  Lola Smits Trainee

  Faculty of Science

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  Bart de Smit Vice Dean / professor of Algebra and number theory

  Faculty of Science

• Human skin equivalent barrier optimization Research project

  The currently available in vitro generated human skin equivalents resemble the human skin in many aspects. However, some essential barrier characteristics do not fully mimic the native barrier. Consequently, the human skin equivalents cannot be used for screening of drugs for skin penetration.

• Knowledge of DNA repair in the fight against tumour cells Research Dossier: Collaborative and effective drug development

  What is the most effective way to eliminate tumour cells? The DNA repair mechanism could play an important role in increasing the effectiveness of chemotherapy in the fight against cancerous cells. If we are to influence this mechanism, we need fundamental knowledge about how the mechanism works.

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  Hermelijn Smits Professor Host-commensal Interactions and Immune Modulation

  Faculteit Geneeskunde

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  Heleen Smits Scientific Information Specialist

  African Studies Centre

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  Maaike Smit-Maaroufi Admissions Officer

  Student and Educational Affairs (SEA)

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  David Lifshitz Smit PhD candidate / self funded

  Faculty of Science

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  Ilse Lagerweij-Smit Lecturer

  Faculty of Law

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  Rinske Smits Study adviser

  Faculty of Humanities

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  Lieke Smits Postdoc

  Faculty of Humanities

• atopic dermatitis: investigating the role of filaggrin in the skin barrier Research output

  Promotor: Prof.dr. J.A. Bouwstra, Co-promotor: Dr. A. El Ghalbzouri

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  Ivo Smits Professor of Arts and Cultures of Japan

  Faculty of Humanities

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  Felix Smits Researcher

  Faculty of Science

• Barrier properties of an N/TERT based human skin equivalent Research output

  Human skin equivalents (HSEs) can be a valuable tool to study aspects of human skin, including the skin barrier, or to perform chemical or toxicological screenings.

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  Maaike Smit-Beemsterboer Study adviser

  Faculty of Governance and Global Affairs

• The importance of free fatty acid chain length for the skin barrier function in atopic eczema patients Research output

  An important feature of atopic eczema (AE) is a decreased skin barrier function. The stratum corneum (SC) lipids - comprised of ceramides (CERs), free fatty acids (FFAs) and cholesterol - fulfill a predominant role in the skin barrier function.

• Unlocking the secrets of DNA repair: Sarah’s curiosity might lead to new cancer treatments News - 7 November 2025

  How do cells repair their damaged DNA—and what happens when that process is hindered and cancer arises? Sarah Moser has taken a closer look during her PhD, uncovering surprising insights that could help improve future cancer treatments.