Current research at the Skin Barrier and Vaccination group.

To maximise your personal development, we ensure tutorials are small-scale and staff members extremely accessible. In year one, you’ll have an average of 12 contact hours, half of which comprise lectures (in English) and the remainder tutorials (optionally Dutch or English).

Learn how to apply for the MSc in Nationalism, Ethnic Conflict and Development at Leiden University: step‑by‑step procedure, submission via Studielink, and next steps.

Control of infectious diseases poses continuous challenges for human health.

How can we implement the technique of pharmacological resting-state fMRI to improve the diagnosis of dementia?

How are digital risk-profiles developed and used in practice?

In this thesis, we will utilize embryonic zebrafish tumour models to understand the interaction between engrafted human cancer cells and macrophages from the host, test drug administration modalities and anti-cancer efficacies of newly-developed PDT and PACT compounds, and test a light-triggered liposomal…

Professor Andrew Webb has been appointed Simon Stevin Master 2017 by the Netherlands Organisation for Scientific Research, an award that carries a prize of 500,000 euros. Webb, who is Professor of MRI Physics at Leiden University Medical Center (LUMC), will use this funding to focus on developing new…

Sphingolipids are important membrane compounds with a variety of functions. In mammalian cells, different enzymes are involved in the metabolism of sphingolipids, but interruption of this metabolism process leads to different diseases.

Promotor: Prof.dr. T. Hankemeier, Co-Promotores: T. Reijmers, L. Coulier

Pharmacologist Amanda Foks is one of the ten talented scientists who received a Dekker grant from the Hartstichting. She receives €427,000 to find a way to rejuvenate immune cells to prevent infarcts. Foks was nominated as Discoverer of the Year in 2016.

How do pathogenic mycobacteria alter lipid metabolism in human cells and patients, and which disrupted pathways could be targeted for new antibiotics?

This study attempts to understand how indigenous community institutions pose an important role in sustainable community-based development, including the integration between local culture and development.

The Power and Pains of Polysemy: Maritime Trade, Averages, and Institutional Development in the Low Countries (15th–16th Centuries) investigates the development of General Average and other so-called Averages in the Low Countries on the eve of the early modern period, showing how the various varieties…

Improving health, enhancing well-being and reducing health disparities across society.

Supervisor: Maarten Doornbos

Kinase inhibitors are key therapeutic agents, particularly in oncology, yet their clinical efficacy is often hampered by off-target effects and limited understanding of their cellular target profiles.

Religion, Class, and the Postwar Development of the Dutch Welfare State. Dennie Oude Nijhuis.

EU foreign policy has become increasingly politicised over the past years, amongst others as a consequence of the succession of crises. Crises may engender processes of crisis framing and contestation. This article focuses on how the policy demands being voiced in these processes of contestation are…

The current projects of the Molecular Physiology group focus on proteins of the endocannabinoid system, kinases and antibacterial targets. MSc- and BSc-students can contact Jessica van Krimpen-Kraaijenoord to apply for research internships.

Health is a wonderful gift, both for humans and for society. If we are able to prevent both physical and mental illnesses, we can spare a lot of suffering and fight rising health costs. Social scientists and physicians in Leiden are working closely together to conduct research on the human mental, behavioural…

In this project, the hypothesis that language contact crucially impacts the development of spatial grammar and phonology is investigated.

In his thesis Tjandra analuses the development of labour law in Indonesia. He focusses on the developments after the fall of the Soeharto regime (1998), the so called reformasi period.

Decision support tool for cell therapy commercialization and business development

This thesis reports on a study that examined the development of L1 teachers’ practical knowledge when they researched and implemented concept-context rich education in an action-research setting.

Research in this group, headed by Gerard van Westen, focusses on computational methods integrated in different parts of the drug discovery process. More specifically, topics include innovative treatments for cancer, selectivity modeling, translational research, allosteric modulation, drug resistance…

Although the world has made tremendous progress in health, education, sanitation and hygiene, global public health challenges still exist. Disparities in health exist between and within nations as evidenced by inequalities in disease burden, mortality, nutrition and environmental well-being. How does…

Source: Eur J Med Chem (2015)

About nine million people worldwide contract tuberculosis each year. Research into new treatment for this disease has received fresh stimulus with more efficient techniques and a new understanding of how the tuberculosis bacteria works.

Leiden University and Leiden University Medical Center have joined the Netherlands Centre for One Health (NCOH), further strengthening the academic network in which such problems as antimicrobial resistance are studied.

Lecture

This is an Erasmus+ International Credit Mobility project of Leiden University’s Faculty of Medicine with Kilimanjaro Christian Medical Center in Tanzania.

Joining forces for a healthier The Hague

The major aim is to determine the psychophysiological responses to stress and stress-management interventions and to examine the role of stress and stress-related psychophysiological mechanisms (e.g., cognitions, behaviors, and physiological stress responses) in both healthy and medical populations.

Professor Thomas Hankemeier and his international research team HYPERMARKER have received a 10m-euro grant from Horizon Europe and UK Research and Innovation.

Schistosomiasis is an acute and chronic disease caused by blood dwelling parasitic trematodes of the genus Schistosoma, and it is classified as the second most socioeconomically devastating parasitic disease, second only to malaria.

Contact us about initial teacher education, educational research and teacher professional development

The potential of liposomal cancer vaccines

Our research aims to develop drugs that boost the host immune response to better defend us against mycobacteria.

This thesis describes the design and development of subunit‐selective inhibitors of particular catalytically active subunits of human constitutive proteasomes and immunoproteasomes.

The division of BioTherapeutics consists of the former divisions Biopharmaceutics and Drug Delivery Technology.

The Division of Systems Pharmacology and Pharmacy (SPP) aims to develop precision medicine approaches to characterize and predict variation in treatment response and enhance translational drug development strategies.

The Cardiovascular Pharmacology research group headed by Ilze Bot aims to elucidate the mechanisms that underlie atherosclerotic plaque destabilization, which is the key process that leads to acute cardiovascular syndromes such as a myocardial infarction or stroke.

Nanoparticles can be used as delivery systems for both small molecules and macromolecules such as proteins, peptides or oligonucleotides. This thesis focuses on the use of liposomes, nanometric vesicles formed by a lipid bilayer enclosing an aqueous core. Liposomes are highly versatile delivery syst…

Master projects are available in

Microglia support the central and peripheral nervous system by forming the first line of defense against hazardous events. Microglia are increasingly acknowledged as critical players in neurodegenerative diseases, highlighting them as potential therapeutic targets.

In this thesis, we aim to shed light on the diverse and often opposing roles of integrin α3β1 in cancer.

Within the LUMC medical research profile Translational Neuroscience innovative multidisciplinary research is performed on a number of severe disorders of the brain, nerves and muscles.