On the 16th of December, Ruixue Wu successfully defended a doctoral thesis. Leiden University Centre for Linguistics congratulates Ruixue on this achievement!

The major and ultimate aim of metabolomics is to obtain an answer to a specific biological or clinical question.

Promotor: G.A. van der Marel, Co-promotor: J.D.C. Codée

On the basis of the characteristic aspects of a picture, certain computers can tell us what the picture is showing. They can learn this in the same way that young children are able to learn to recognize images. Further improving these techniques opens the way to a whole range of new applications. Biology…

A study by a Leiden-Wageningen group shows that present-day humans are biologically poorly equipped to deal with the toxins they are regularly exposed to in smoky environments: compared to earlier hominins, we modern humans are probably even worse off. The study appeared in Molecular Biology and Evolution.…

Former Member of Parliament Lammert van Raan (PvdD) and alumna Eva Floris gave a guest lecture on the 13th of May on the Ecocide penalisation initiative bill. During the lecture, they discussed the idea behind the bill, the objections from politicians and the business community and the advice of the…

Worldwide, countries are barely prepared for major borderless crises such as extreme natural disasters or other unexpected calamities that destabilise society, Professor of Political Science, Arjen Boin, warns. In his inaugural address on 23 October he makes some recommendations.

On 22 September, the Social Justice Expertise Center and the Dutch Association on Labor Rights (VVA) brought together eighty (Dutch) labor law lawyers to discuss the relationship between corporate social responsibility (CSR) and fundamental labor rights.

Er is een nijpend cellen- en personeelstekort in Nederlandse gevangenissen. En dit is niet voor de eerste keer. Miranda Boone, hoogleraar criminologie en vergelijkende penologie, sprak met Trouw over de problematiek: ‘Het aantal gevangenen is het resultaat van beleid.’

To this day, all cyclophellitol-based inhibitors and ABPs have been close analogues of their natural substrate counterparts. As a result, these probes showed high selectivity towards their target glycosidases.

The glycosylation reaction is a pivotal reaction in creating new and complex oligosaccharides.

Bachelor and Master students of all chemistry related studies are more than welcome to take part in our research activities. We have projects on design and synthesis of biologically relevant compounds within an ongoing research project. Supervision, following the apprentice/teacher model, is one of…

Glycosidases are essential in fundamental biological processes and are responsible for the degradation of most (oligo)saccharides, glycolipids and glycoproteins.

Optimization, mechanisms of action and predictors of the outcome of light therapy in depression: A multicenter randomized trial

Learning a programming language is challenging. Even one of the first –but crucial– concepts to learn, variables, is hard to grasp. Variables can represent different roles and functions within a code and need to be named appropriately to support code comprehension and debugging.

Metal-containing molecules combine geometrical features and a reactivity that are inherently different from that of organic molecules. My research focuses on light-activatable metal-based anticancer drugs and metal-functionalized liposomes. Light is a very selective way to activate photosensitive drugs…

Promotor: Prof.dr. P.G.L Klinkhamer

The research in the Biosyn group is focused on the design, synthesis and function of the four major types of biomolecules: nucleic acids, carbohydrates, peptides and lipids and hybrid structures thereof. These biomolecules and their derivatives are used in drug discovery and chemical biology, to develop…

Promotor: Prof.dr. H.A.G. Wijshoff

Your brain responds in a predictable way when it encounters new or difficult tasks. This unique book teaches you concrete techniques rooted in cognitive science that will improve the way you learn and think about code.

Promotor: A. Kros

The emergence of complex diseases resulting from abnormal cell-cell signaling and the spread of infectious diseases caused by pathogens are significant threats to humanity. Unraveling the dynamic mechanisms underlying cell-cell signaling and infectious disease spreading is crucial for effective disease…

Parkinson's disease is the second most common neurodegenerative disease in the world. One of its symptoms is the loss of dopaminergic neurons in the substantia nigra pars compacta.

This study is a critical discourse analysis of the misogynistic narratives shared by three incel violent extremists.

Promotor: Prof.dr. F.S. de Boer, Co-promotor: D. Clarke

Making systems biology modelling a central pillar of research in biology

For many years, human rights have been considered a playing field in which states were the most important actors. In the present day society, this has changed as a consequence of globalization and the rise of multinational enterprises (MNEs). Protection of fundamental labor rights in global supply chains…

Chemical biology research at the Leiden Institute of Chemistry is aimed at understanding biological processes at the molecular level to strengthen the knowledge base of human health and disease. The approach to achieve this goal is a fundamental chemical one; with the aid of chemical probes biological…

On 28 June, Willem Ruijs defended the thesis 'Pawnbroking'. The doctoral research was supervised by r Pim Rank and Willem van Boom.

Identifying natural plant-associated bacteria that provide targeted inhibition of pathogens through the production of antimicrobial peptides.

The master’s specialisation Biodiversity and Sustainability at Leiden University provides students with a much better understanding of the biological processes which are essential for creating a sustainable society.

The master's specialisation Bioinformatics at Leiden University focuses on research, development and application of computational tools and approaches for expanding the use of biological, medical, behavioral and health data.

Microbial Sciences' contribution to the Bioactive Molecules research theme is to discover new bioactive molecules and enzymes and unravel their mechanisms of action, regulatory networks, and the (bio)synthetic pathways required for their production.

All LIAS members and visitors are kindly requested to familiarize themselves with the information provided below, to the level of detail they feel is appropriate to their situation. This information overlaps in part with the University’s web pages on scientific integrity.

Lecture

The integrity and reliability of academic research are of fundamental importance to the university.

On the basis of the characteristic aspects of a picture, certain computers can tell us what the picture is showing. They can learn this in the same way that young children are able to learn to recognize images. Further improving these techniques opens the way to a whole range of new applications. Biology…

What are the historical roots of the indivisibility of pledge and hypothec?

Promotor: Prof. dr. A.G.G.M. Tielens

For many years, human rights have been considered a playing field in which states were the most important actors. It is they who in multilateral relations, such as the United Nations (UN), the World Trade Organisation (WTO) and the International Labour Organisation (ILO), have written international…

In this thesis, we show how MRFM can usefully contribute to the field of condensed-matter.

Investigating domestic crafts and subsistence activities through experiments and material analysis