Our educational team has been awarded an ICTO-grant of €12000 for the LACDR for flipping the Biochemistry 2 classroom.

In photoactivated chemotherapy (PACT), a biologically active compound is caged by a light-cleavable protecting group.

Twenty years from now, the world population is estimated to be around 8.7 billion people, compared to the current 7.3 billion. In combination with the improvements in living standards and the corresponding growth in consumption, this will result in an enormous increase in the demand for food, consumables,…

The main goal of the research described in this thesis was the development of new photoactivated chemotherapy (PACT) ruthenium(II) complexes bearing a non-toxic photolabile ligand.

This thesis introduces the concept of

In this thesis, we consider various (electro)chemical phenomena at surfaces and nanoparticles and their underlying atomistic processes, which we studied using first-principles methods such as density functional theory.

This thesis advance our understanding and the application of molecular catalysts relevant to the reduction of oxygen as well as reduction of nitrite.

Cyclic peptides are investigated as a platform to induce different orientations between various ligands.

Understanding the formation and preservation of Pleistocene fire traces through laboratory-based experimental research

Leiden Professor of Molecular astrophysics Ewine van Dishoeck has been awarded an Advanced Grant by the European Research Council (ERC). She has been awarded 2.3 million euros in research funding for the MOLDISK programme. Within this programme, Van Dishoeck wants to connect chemistry and physics in…

Promotor: E. Bouwman, Co-promotor: S. Bonnet

On the occasion of the Women & Girls in Science Day, BBC Science Focus Magazine highlighted 6 prominent female chemists. Among them is Leiden professor Ewine van Dishoeck: 'Astrochemist investigating the building blocks of life'.

This thesis describes the use of an activity-based proteomics method to study the endocannabinoid system.

Despite being the second largest transmembrane protein family after GPCRs, the SLC superfamily has only gained significant attention in early drug development over the past decade.

Less than 1 in 10 drug candidates that enter phase 1 clinical trials actually gets approved for human use.

Are you interested in the minor Cultural Anthropology and Development Sociology? Find out more about admission and application.

The channel through which two cell components exchange material appears to form at the edge of their contact surface, and not in the middle. This was discovered by the Leiden physical chemists Jelger Risselada and Edgar Blokhuis together with researchers from the University of Lausanne in Switzerland.…

Synthesis and application of chemical biology tools to study immunomodulatory signaling lipids.

This thesis describes the use of bioorthogonal proteins in immunological settings. It provides an introduction towards the field of protein modification, which was used throughout the thesis for the expression of proteins containing unnatural amino acids.

Although Sander Wezenberg just started working in Leiden in March this year, he already managed to win a Vidi grant from NWO. Inspired by nature, Wezenberg wants to bring synthetic molecules to life and teach them to communicate. But who exactly is Wezenberg and what drives him?

Alumnus Vincent Renken studied Bio-Pharmaceutical Sciences in Leiden and is now co-founder of an outdoor escape room company. ‘I asked myself: do you want a standard life or an adventure?’

Pseudomonas Aeruginosa is a Gram-negative bacterium which can form biofilms, increasing its resistance against antibiotics and the host immune system. Polysaccharides are an integral part of this biofilm, one of these polysaccharides is called Psl. PslG is a glycosidase, able to cleave this polysaccharide,…

Dr. in Biomedical NMR spectroscopy, LUMC, Leiden - The Netherlands

Young children, adolescents and students may experience learning difficulties as a result of lack of sleep. Dr Kristiaan van der Heijden investigates sleep problems and solutions for various age groups.

Large parts of the research described in this Thesis aims at the development of oligopeptide-masked toxins and their in situ immunoproteasome-mediated activation.

Exploring the synergy of light therapy and exposure psychotherapy to enhance PTSD treatment outcomes.

The Business Studies Seminar (BUSS) Series features invited scholars’ seminars on organizational, legal, and technological research. In 2024, the Organizational and Entrepreneurial Behavior, Technology and Innovation, and Corporate Governance and Strategy research groups will invite diverse speakers…

The Institute of Criminal Law and Criminology is located in the Kamerlingh Onnes Building (KOG).

Metal complexes and 2D materials like graphene were combined to produce structures that can function as sensors.

Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt

A consortium of researchers from the Leiden Institute of Physics (LION), the Institute of Biology Leiden (IBL), and the Leiden Institute of Chemistry (LIC) received a FOM program grant to develop a novel way of studying individual proteins inside a cell using gold nanorods.

The "Van Marum Colloquia" are a collaborative lecture series between the LION and LIC institutes, focusing on fundamental and applied surface science.

Management of Impacts on Biodiversity: What are the effects of light pollution from cities and bridges and noise pollution from passing vessels and nearby road traffic on migratory fish passage and spawning in rivers?

Education & outreach

SMR can be used to measure the mass of adsorbed protein to nanoparticles with a high precision in the presence of free protein.

In this on-line dissertation, jazz saxophonist Dick de Graaf investigates a variety of compositional and improvisational models and techniques in contemporary jazz and Western art music, and discusses possible applications of these materials in current jazz practices.

What are the precise identities, possibilities and current practice examples of the various time frames in music and what bearings do they have individually and in combinations on the speed of the music?

ASLU 29 Maarten E.R.G.N. Jansen, Valentina Raffa (2015)

Animal Sciences’ contributions to the Biodiversity & Evolution research theme include evo-devo research, the evolution of cognitive and behavioural traits, and the evolutionary mechanisms of stress adaptation. This research involves both indoor and outdoor studies.

Bachelor and Master students of all chemistry related studies are more than welcome to take part in our research activities. We have projects on design and synthesis of biologically relevant compounds within an ongoing research project. Supervision, following the apprentice/teacher model, is one of…