The studies reported in this thesis were situated in the context of an innovation of Dutch secondary school biology curricula. As in any innovation, the practical knowledge of teachers determine the outcomes through the decisions they make while planning and teaching their lessons. The aim of the studies…

As a non-invasive genetic method, eDNA based approaches have become an important component of ecologists' and environmental managers' toolkits for biomonitoring in conservation and an increasingly important source of ecological knowledge.

Vast, often populated, areas in dryland ecosystems face the dangers of desertification.

There are millions of gene clusters that encode the biosynthesis of bioactive natural products, with the vast majority yet unknown. How can we prioritize them to discover new chemical space for antibiotics? For this we will set up a pipeline based on federated learning (AI), synthetic biology and bioactivity…

Promotor: J. van der Greef; Co-promotor: E. van Wijk, M. Wang

This project is situated within the context of an innovation of the biology curriculum in Dutch secondary schools. The main purposes are (1) to clarify the relation between teachers’ practical knowledge and the decisions they make when planning and implementing their lessons and (2) to develop a professional…

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Promotor: Prof.dr. H.P. Spaink Co-promotor: Dr. B.E. Snaar

To what extent and how do identity processes influence health behavior?

Today, 13 May 2024, Leiden University’s Executive Board is publishing the advice of the committee that investigated reports of unacceptable behaviour and breaches of academic integrity. These reports were about a professor from the university and their partner (a former member of the university staf…

Can Zebra finches learn to distinguish two very similar Dutch words? Research by behavioral biologist Verena Ohms proved that they can identify 'wit' and 'wet'. Ohms published her findings in

Promotores: G.R. de Snoo, W.T. de Groot, Co-promotor: C.J.M. Musters

Climate change is a challenge for both current and future generations. New biological resources have to be developed in order to meet the demand for energy as well as the demand for food.

Promotor: J.G.E.M.Fraaije, Co-promotor: A. Kros

Carbohydrates, alongside proteins and nucleic acids, constitute a crucial and versatile family of biomolecules present in all life forms. They manifest as monosaccharides, oligosaccharides, and polysaccharides, covalently bonded to proteins and fats. Carbohydrates are integral to plant and arthropod…

Engineering an efficient microbial enzymatic polyethylene degradation pathway via an innovative combination of biochemistry and computational biology tools for enzyme discovery and characterization.

Hybrid zones occur where two species meet and produce offspring (hybrids). Typically, hybrids show a considerable reduction in fitness. In this thesis two hybrid zones are treated.

A neurobiological perspective on individual differences in social competence

Honorata Mazepus, Assisstant Professor at Leiden University, researched the topic of Madisonian Judgments in Five Cultures, together with three other authors.

University is often a period of sexual exploration and experimentation, generally to the satisfaction of all involved. But sometimes you want it and the other doesn’t. Or vice versa. Or you can’t really tell. This is what the Safe Space play at Theater Ins Blau was about on 11 October. And: can your…

Streptomyces present a valuable platform for natural product discovery. Lugdunomycin is a novel angucycline-derived polyketide from Streptomyces sp QL37, with unprecedented skeleton and antimicrobial activity.

The cannabinoid receptor type 2 (CB2R) is associated with several inflammatory diseases with an unmet medical need (e.g. Alzheimers, multiple sclerosis, reumatoid arthritis). Development of new chemical biology strategies to study this protein is essential to aid future development of drugs for these…

Please note that the course Molecular Biology for Physics will start on Monday 5 February. Please check the schedules for the time and location!

Learning from nature and utilizing microbial biodiversity to identify and characterize enzymes for degradation and upcycling of plastics and other polymeric materials.

The researchers examine the Council of the European Union's voting behaviour between 2010 and 2021 and the impact of different independent variables.

This is a difficult time. Above all, for all those directly involved in this horrible case – unacceptable behaviour by a professor and his removal from the University – the case we went public about on 18 October and that has been reported in the media. This is painful and tough for the complainants…

This thesis describes the synthesis and biochemical evaluation of a variety of cyclophellitol based activity-based probes and inhibitors targeting various endo- and exo-acting retaining glycosidases. In the last two decades a variety of probes and inhibitors for (hemi)cellulose degrading enzymes have…

How does invasive hybridization affect threatened native species?

A professor from Leiden University has subjected various colleagues to intimidating and unacceptable behaviour for a longer period. These are the findings of an investigation carried out by the University’s independent Complaints Committee for Unacceptable Behaviour at the request of the Executive Board…

Tackling key challenges of Chemical Biology and Medicinal Chemistry to aid drug discovery is one of the focus areas of Leiden University. To this end, the Leiden Early Drug Discovery & Development network (LED3) was established by the Leiden Institute of Chemistry (LIC), the Institute of Biology Leiden…

The United Nations Office for Disarmament Affairs (UNODA) has published the 2017 issue in their Civil Society and Disarmament series, titled Voluntary, Non-Binding Norms for Responsible State Behaviour in the Use of Information and Communications Technology: A Commentary. The series aims to provide…

The Faculty of Social and Behavioural Sciences has become a lot healthier, thanks to the first Healthy Faculty event on 29 and 30 October, 2015. Health Psychology master’s students organised workshops for both students and staff. Many of them attended these inspiring workshops and already put the gained…

New research published in the Journal of Leukocyte Biology suggests that these changes to the behavior of the immune system are persistent and can continue even after diet is improvedAlmost everyone knows that improving your eating habits will most likely improve your health. What most people may not…

A study on the development of prosocial behaviour.

During post-embryonic development into adults, animals face an environment that fluctuates constantly. For example, in nutrient availability, temperature, and osmolarity (e.g., salt concentration).

The effects of anthropogenic noise on interactions between predators and their prey are still little understood.

On the 1st of October a new project funded by the Joint Industry Programme (JIP) started at the IBL on the potentially negative effects of sound on fish. Behavioural biologist and bioacoustic specialist Dr. Hans Slabbekoorn leads the international research team.

This thesis introduces the concept of

Mapping the neural mechanisms underlying social motivations of adolescents and adults

Political scientists Joop van Holsteyn and Tom Louwerse (Leiden University) find that the Dutch government is having a hard time coping with referendum outcomes in general, and ‘anti-European’ sentiments among voters in particular.