Psycho-physiological reactions to stress.

The electrochemical oxygen reduction reaction (ORR) is an essential half-reaction for the utilization of hydrogen as a sustainable fuel, via the conversion of hydrogen to electrons and protons facilitated by the ORR. In the most common fuel cells, the ORR is requires high loadings of non-abundant platinum…

The sustainable production of hydrogen could potentially be made more efficient by adding a cleverly chosen salt to the process. Researchers at the Leiden Institute of Chemistry (LIC), in collaboration with physicists at the University of Twente, have discovered that the type of salt present in the…

Promotor: G. J. Kroes

The main research theme in the group of Dennis Hetterscheid is to understand and mimic bioinorganic multi-electron processes that are relevant to our future energy infrastructure. Reduction of protons generates hydrogen that can be used as a chemical fuel. Alternatively to gaseous hydrogen, the reduction…

Individual molecules are extremely hard to see through feeble fluorescence. Tiny gold nanorods serve as new antennas to intensify their signal 500 times. Publication on 24 February in Angewandte Chemie.

Financial support that wealthy countries provide to poorer countries in order to help them combat climate change and the associated emissions was the central topic of this year's UN Climate Change Conference in Baku. Annemarie Drahmann, Associate Professor of Constitutional and Administrative Law, discussed…

In surface science there is great effort to move from studying simple, flat model surfaces in vacuum to investigating more complex model catalysts in gas environments (in situ). This thesis gives three examples of such studies using microscopy and spectroscopy.

Imagine we could do what green plants can do: photosynthesis. Then we could satisfy our enormous energy needs with deep-green hydrogen and climate-neutral biodiesel. Scientists have been working on this for decades. Chemist Chengyu Liu will receive his doctorate on 8 June for yet another step that brings…

Promotores: Prof.dr. H.J.M. de Groot, Prof.dr. J. Matysik (Universitaet Leipzig)

The dissociative chemisorption of a molecule on a transition metal surface represents a rate-limiting step in many heterogeneously catalyzed processes, whereby most chemicals are made. In spite of the importance of this reaction, an accurate first principles approach to modeling it does not yet exist.…

Can the conditioning paradigm be used for checkpoint inhibition cancer treatment?

Promotor: M.T.M. Koper, Co-promotor: L. Juurlink

Promotor: M.T.M. Koper, Co-promotors: A.I. Yanson, L.B.F. Juurlink

A full overview of THEOR PhD theses.

Central in coordination and organometallic chemistry is the synthesis of new chelating ligands, the synthesis and characterization of metal complexes with these ligands, and the study of their properties. An important goal in my research is to create understanding of the relation between the structures…

Promotor: P.M. Brakefield

Vast, often populated, areas in dryland ecosystems face the dangers of desertification.

Climate change and energy transition were an important theme of the Dutch provincial elections: how should we invest in new sources of energy? Leiden University conducts multidisciplinary research into renewable energy solutions. Read more about this in the ‘Renewable Energy’ research dossier.

Active-site directed probes are powerful in studies of enzymatic function. We report an active-site directed probe based on a warhead so far considered unreactive.

N-acylethanolamines (NAEs), including N-arachidonoylethanolamine (anandamide, AEA), N-palmitoylethanolamine (PEA) and N-oleoylethanolamine (OEA), are signaling lipids that play an important role in different physiological process.

We report new computational and experimental evidence of an efficient and astrochemically relevant formation route to formaldehyde (H2CO). This simplest carbonylic compound is central to the formation of complex organics in cold interstellar clouds and is generally regarded to be formed by the hydrogenation…

Although sexual abstinence before marriage is no longer the central message in The Netherlands the affective relationship as a criterion for professionals within criminal justice can be seen as a more contemporary version of marriage.

The

The cellular metabolism of immune cells constitutes an important part of their proper function and activation. Using T cells as an example, this phenomenon is highlighted by the metabolic reprogramming that occurs in these cells upon activation.

Using biomethane to produce ammonia, a crucial chemical in agriculture, could drastically reduce the climate impact of the process. In a study published in One Earth, researcher Robert Istrate shows it’s even possible to make ammonia production net-zero or carbon negative.

Leiden University is a integral part of the community and contributes to a sustainable society. Over the coming years our University will become even greener.

The Leiden University Green Office has some great news: you can now make the most environmentally-friendly search engine - Ecosia - your default on a public LU computer!

The world we live in is changing in many aspects at an ever-increasing speed. And it will continue to do so. How do we anticipate these changes, such as the increase in atmospheric CO2, the extinction of species and industrialisation?

Promotor: E.F. Smets Co-promotor: J. Geml

This guide relays information on tips and tricks for traveling by train and bus, and which online tools you can use for sustainable travel and trip planning.

MICRO-biome climate smart applications: Can we use indigenous microbial rice communities to reduce methane production in agricultural settings?

Leiden chemist Marc Koper is the winner of the 2017 Faraday Medal for his significant contribution to electrochemistry, from fundamental science to practical application.

After hard work in the lab, Chemist Tirong Guo has developed a group of materials that provide a stable and efficient foundation for artificial photosynthesis. Will this enable the large-scale production of hydrogen and other useful compounds in the most sustainable way possible? Guo will defend her…

PhD defence

Atherosclerosis (thickening of the artery wall) is the most common cause of heart attacks or strokes, and one of the most common causes of death in the western world. People with this condition have to take medicine all their lives, so a vaccine for atherosclerosis would be a breakthrough.

The central theme of Rik Mom’s research group is to identify what the electrode-electrolyte interface looks like when electrocatalysis is taking place. Using specialized forms of Raman and X-ray spectroscopy, we study the chemical state and bonding environment of the electrode surface and near-surface…

Research at the MCBIM group is comprised of the following research themes:

This thesis describes the synthesis, analysis of various tetrazine bearing compounds and use in bioorthogonal chemistry.

In the last decade, the redox interconversion between metal thiolate and disulfide compounds has been extensively investigated for copper, but not for other transition metal ions.

In a typical glycosylation reaction, a donor is activated to form a (variety of) electrophilic species which can react with a nucleophilic acceptor, following a reaction mechanism having both SN1 and SN2 character.

Promotor: A. Doelman, Co-promotor: V. Rottschäfer

Climate change is one of the largest challenges faced by humanity. To combat this research into alternatives to fossil fuels is ongoing. Dihydrogen is considered a good alternative fuel, since its burning only forms water.

In this article Fisher, Klein & Codjo introduce the FOCUSdate Project and they show how the sentiment data provide unique abilities to analyze Russia's and Iran's reactions to US policies and events and NGO human rights campaigns.

In the search for sustainable energy solutions, the idea of artificial photosynthesis has been proposed as an approach with which to use water and sunlight to produce hydrogen.

The focus throughout this thesis will be on gathering fundamental studies of the detailed structure and composition of the electrode/electrolyte interface effect on the rate and mechanism of key electrocatalytic reactions.

Reactions and reaction times in cognitive tasks.

Marc Koper’s research focuses on electrocatalysis and electrochemical surface science for sustainable energy and chemistry. Reactions of interest are the redox reactions of the oxygen/hydrogen cycle (water oxidation, hydrogen evolution), the carbon cycle (reduction of carbon dioxide, oxidation of small…

Parkinson's disease is the second most common neurodegenerative disease in the world. One of its symptoms is the loss of dopaminergic neurons in the substantia nigra pars compacta.

Stars and planets form within cold, dense clouds of gas and dust drifting through interstellar space. Although dust makes up only a small fraction of this material, it plays a key role in shaping the chemical evolution of these environments.