Promotor: Prof.dr. J. Kuiper, Co-Promotor: S.C.A. de Jager

We are looking for students who are 16 years or older and are studying at a Dutch mbo, hbo or university. Our aim is to gain insight into the needs and perceptions of students regarding stress and burnout. In short, we aim to carefully listen to the students’ needs: how can we help you?

Are you curious about how health, behaviour and our living environment are connected? At Leiden University, you’ll explore how people grow up, age and live together in a changing world. From mental health to healthcare innovation, from lifestyle to healthcare policy: you’ll learn to understand societal…

Are you curious about how health, behaviour and our living environment are connected? At Leiden University, you’ll explore how people grow up, age and live together in a changing world. From mental health to healthcare innovation, from lifestyle to healthcare policy: you’ll learn to understand societal…

The research of this PhD project can be subdivided into two main disease areas: migraine and stroke. For both we will be investigating how artificial intelligence (AI) and machine learning (ML) techniques can be used to study these afflictions, their (early) detection, and their potential treatment.

Atherosclerosis is a progressive disease resulting in the formation of an arterial plaque. Despite lipid lowering, recurrent cardiovascular events remain a risk. While atherosclerosis is primarily lipid-driven, the immune system plays a critical role in the pathophysiology.

This thesis focuses on amyloid proteins, a class of proteins that convert into amyloid fibrils.

The financial system needs complexity theory to predict economic crises like the 2008 meltdown. An international team of scientists, including Leiden physicist Diego Garlaschelli, state this in a paper published in Science on February 19th.

When mosquito eggs hatch in nutrient-rich water, the mosquitoes are larger and they can also fly further. That is the first conclusion of a study from by the Netherlands Centre for One Health (NCOH) by PhD-student Sam Boerlijst.

How can we as a society prevent suicide? According to Professor of Suicide Prevention Renske Gilissen, a better understanding and targeted action could help save lives.

A study into the impact of historical socioeconomic changes on the respiratory health of past Dutch populations (ca. 470-1850 CE)

Professor by Special Appointment of Clinical Neuropharmacology Geert Jan Groeneveld will deliver his inaugural lecture entitled ‘The importance of the biomarker’ on 11 March 2022. According to him, new genetic knowledge will revolutionise drug research.

The Netherlands has a long history of mosquito-borne diseases, particularly malaria, until 1970 when it was declared malaria-free.

Can drugs that target host signaling pathways be used to eradicate antibiotic-resistant bacteria?

Five talks will be given during the Leiden Science Family Day: two children's lectures and three lectures for adults. Will you be there ?

New funding allows IBL-researcher Herman Spaink to purchase a measurement device for more studies on human diseases such as cancer and tuberculosis using zebrafish as the model system.

The World Food Programme (WFP) uses mobile technology to predict potential famine more rapidly. Leiden University's Centre for Innovation is developing a Leiden University online course for professionals to learn the technique.

Aceruloplasminemia is a very rare, genetic disease accompagnied with iron accumulation that causes movement disorder and brain damage at early age.

Patients with the same illness often receive the same treatment, even if the cause of the illness is different for each person. This represents a new step towards ultimately being able to offer every patient more personalised treatment.

On 3 April, Professor Syed Faisal Ahmed from the Leiden University Medical Center (LUMC) will give his inaugural lecture ‘Strength in Numbers’. He will emphasise the benefit of registries to rare disease research.

Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.

Leiden Professor of Translational Rheumatology Hans Ulrich Scherer has one foot in the clinic, where he helps patients, and the other in the lab, where he supervises researchers. He bridges these two worlds in his hunt for autoimmune rheumatic diseases.

The Netherlands X-omics Initiative is a new facility as part of the National Roadmap for Large-Scale Research Infrastructures. It is partly funded by NWO with a total budget of 40 million euro. The project started on September 2018 and will last for ten years.

A step-by-step approach to building confidence in anxiety-prone young children.

How do protein modifications work together to repair DNA, and what can we learn about these interactions to better understand disease?

The studies described in this thesis deal with glycosidases, in particular alpha-galactosidases.

A combination of two potential drugs gives hope of a 'super blockage' of an over-active immune system, Leiden researchers report in Nature. The breakthrough came from the crystallisation of a membrane protein.

Facebook and Google are being pressured more and more to prevent terrorists from accessing and using their platform. Right now, they are developing software that uses artificial intelligence to remove unwanted content. Researchers from Leiden University explain for the NOS how this works, and whether…

The availability of complete plant genome sequences together with the ever increasing amount of data on the molecular, cellular and physiological mechanisms of plant development require mathematical and computational models to obtain a complete overview of and generate new insights into the quantitative…

Parkinson's disease is the second most common neurodegenerative disease in the world. One of its symptoms is the loss of dopaminergic neurons in the substantia nigra pars compacta.

Promotores: Prof.dr. J. Kuiper, Prof.dr. P.H.A. Quax

Cardiovascular diseases are among the most frequent causes of death in the world. The main underlying pathology of cardiovascular diseases is the development of atherosclerosis in the medium and large-sized arteries.

Healthy aging is one of the prime goals in today's society and atherosclerosis is among the greatest causes of morbidity in elderly. Cardiovascular disease patients receiving treatment are often of advanced aged and have an aged immune system, which limits translating experimental findings to the pa…

We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.

Thesis focused on uncovering the underlying mechanisms of the lysosomal storage disorders Gaucher's disease using chemical tools, biochemical assays and lipidomics.

Alireza Mashaghi and his research team have created a new framework to understand shapes of proteins and DNA. With this framework, many diseases can be understood better.

Mapping of bacterial genomes to combat infectious diseases

The Dutch Advisory Committee on Public International Law has, on its own initiative, provided advice to the Dutch government regarding the duty of third states to prevent genocide under the Genocide Convention. The Committe's advice addresses the legal uncertainty in political and societal debates about…

The HOPES study is one of the largest investigations of this kind to date! By studying existing brain scans and data collected form over 4,000 14-25 year olds, the project team hopes to identify specific changes in the brain that make young people vulnerable to suicidal thoughts and behaviours.

A vitamin D deficiency is often associated with smoggy English industrial cities during the Industrial Revolution, but research carried out on skeletons now suggests that the ‘English disease’ was also prevalent in rural areas of the Netherlands. Doctoral defence on 29 January.

PhD defence

In this master programme you learn interdisciplinary approaches to address scientific and societal challenges in the field of (bio)medical sciences. The research in our programme Biomedical Sciences relates to the maintenance of health and prevention of disease. You will acquire a skill set suitable…

Leiden chemists, together with colleagues at the University of York (UK) and Technion (Israel) have discovered a small, sugar-like molecule that maintains the integrity of tissue around a tumour during cancer. This molecule prevents tumour cells from spreading from the primary cancer site to colonise…

Dr. Foks obtained this fellowship for the project “Can promotion of efferocytosis induce regression of atherosclerosis?”, in which she aims to identify novel targets to promote regression of atherosclerosis. This research grant allows her to initiate independent research for the next three years.

Every year, around 40 women are murdered in the Netherlands. The perpetrator is often their partner or ex-husband. Assistant Professor Ellen Gijselaar spoke to NOS News about femicide: 'It’s impossible to prevent all these cases, but you can limit the risk.'

Which plant leaf characteristics are involved in thrips resistance in tomato?

RARE-NL, a new collaboration between university hospitals, hopes to find treatments for rare diseases. Professor Teun van Gelder is representing the LUMC in the initiative.