Central in this thesis are the various forms the research-teaching nexus can take in the university, especially in the Faculty of Humanities. The importance of a strong relation between research and teaching is advocated by many academics, but debate is going on about the forms this strenghthened relation…

We investigate the molecular basis underlying health and disease and provide answers to existing and emerging health problems. Within this theme, we study diseases ranging from rare genetic disorders to cancer and infectious diseases. We make use of a wide variety of model systems and pursue diverse…

Promotor: J.A. Bouwstra Co-promotor: A. El Ghalbzouri

This project envisions a broad evaluation of 20th century models of human development over the life course (ontogenesis, human constitution), including socialist and capitalist conceptions across both Eastern and Western Europe.

A new research line is the development of liquid biopsy fingerprints to predict early Alzheimer’s disease (AD) stage in human in readily accessible body fluids in human (in collaboration with: Dr. Geert-Jan Groeneveld, CHDR; Prof. Elga de Vries, Free University Medical Center; and others).

The Research Handbook on Labour, Business and Human Rights Law edited by prof. Janice Bellace of the University of Pennsylvania and ass. prof. Beryl ter Haar of Leiden University. The book is publisehd in Edward Elgars series on Human Rights.

The routine assumption that Upper Palaeolithic early modern humans in Europe were regular fire users who produced fire at will has never been tested against the archaeological record. Utilizing literature, database and microwear analytical approaches, this project seeks to establish the role and forms…

This PhD project investigates what the universal and variable morphosyntactic properties of linguistic expressions of otherness are and how they can be modelled theoretically.

On 18 March 2020, Hoko Horii defended her thesis ‘Child Marriage as a Choice. Rethinking agency in international human rights’. The doctoral research was supervised by prof. A.W. Bedner and prof. G.A. van Klinken.

How can archaeological datasets reveal the interplay between past indigenous understandings of the surrounding world and resilient and sustainable ways of life in the Isthmo-Colombian Area?

In order to gain insight into the structure and function of the molecular complexes involved in chemotaxis, we use electron cryotomography (ECT). This technique allows us to directly study microbes in their native state at resolutions capable of visualizing individual proteins.

How do plants lure microscopically small 'support teams' into their roots for protection against diseases? And what functions are activated in the microbes and the plants?

Environmental Humanities in the New Himalayas: Symbiotic Indigeneity, Commoning, Sustainability showcases how the eco-geological creativity of the earth is integrally woven into the landforms, cultures, and cosmovisions of modern Himalayan communities.

The writings of Walter Benjamin (1892-1940) are famously and purposely marked by fragmentariness. Paradoxically, a central aim of his work was to connect: all his life he sought to further the integration of scholarship in the humanities which, he believed, had too long suffered from the prevalence…

Heart failure is a major health care problem with high mortality.

Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn, Co-promotor: Dr. M.J.M. Schaaf

Promotor: G.A. van der Marel, Co-promotor: D.C. Codée

Plants are colonized by an astounding number of microorganisms that can provide different life-support functions, including nutrient acquisition and protection against (a)biotic stresses like drought or pathogen attack.

One of the main challenges in the development of an effective anti-cancer vaccine is the generation of an adequate and directed cellular immune response.

The CMCB brings together a diverse range of unique expertise in microbial cell biology. Members of the CMCB investigate both model and non-model organisms, bacteria and archaea, pathogens and non-pathogens.

BACKGROUND: Explant human skin equivalents (Ex-HSEs) can be generated by placing a 4mm skin biopsy onto a dermal equivalent. The keratinocytes migrate from the biopsy onto the dermal equivalent, differentiate and form the epidermis of 1(st) generation Ex-HSEs. This is especially suitable for the expansion…

On Tuesday 23 May 2017, Jasmina Mackic defended her doctoral thesis ‘Proving discriminatory violence at the European Court of Human Rights’. The supervisor of the research is Vice Dean and Professor of Public International Law Larissa van den Herik. A brief summary of her thesis is provided below.

Holtz defended her dissertation ‘Collective human rights as an (onto)logical solution to climate change: reconceptualizing, applying and proceduralizing an overlooked category of human rights’ on 16 October 2025. The doctoral research was supervised by Carsten Stahn and Daniëlla Dam-de Jong.

Using brain imaging to discover the area in the brain that recognizes emotion.

Pericytes, the mural cells of blood microvessels, are important regulators of vascular morphogenesis and function that have been postulated to mechanically control microvascular diameter through as yet unknown mechanisms.

Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.

New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.

Transplantation of labial salivary glands to the eyelids for patients with dry eye appears to give excellent results clinically.

Promotor: Prof.dr. M. Danhof, Co-promotor: O.E. Della Pasqua

Human skin equivalents (HSEs) can be a valuable tool to study aspects of human skin, including the skin barrier, or to perform chemical or toxicological screenings.

The central question in this book is whether there is a human right to family unification.

Een minuscuul cirkelvormig stukje DNA zorgt ervoor dat de darmbacterie Clostridioides difficile resistent raakt tegen een veelgebruikt antibioticum. Dat ontdekten wetenschappers van het Leids Universitair Medisch Centrum (LUMC) nadat artsen hen attendeerden op een patiënt met een moeilijk behandelbare…

To get a feeling of how we operate at LED3 when it comes to Early Drug Discovery, please browse through our case studies. When you select a case study you’ll find relevant contacts.

The high prevalence of pure red cell aplasia in Thailand has been associated with the sharp increase in number of recombinant human erythropoietin (rhEPO) copy products, based on a classical generic regulatory pathway, which have entered the market.

Tens of thousands of soldiers and civilians have died as a result of Russia’s invasion of Ukraine in February 2022 and the continuing armed conflict. Many forms of critical infrastructure have been destroyed. Much of this devastation has been caused by weapons that utilise forms of artificial intelligence…

Supervisor: Natalia Ortiz Zacarías

Extending our current arsenal of antibiotics is key to staying ahead in the arms race between humans and resistant bacteria.

This is the 2017 paperback release of William Michael Schmidli's The Fate of Freedom Elsewhere, which won the 2013 Foreign Affairs Magazine Best Book of the Year.

The 2006 United Nations Convention on the Rights of Persons with Disabilities differs markedly from other forms of international human rights law: it not only protects the rights of individuals but also addresses interpersonal relations and social structures. How did the convention attain this broad…

What do scholars do when they talk about virtues (impartiality, accuracy) or vices (dogmatism, prejudice)?

In the studies described in this study, we introduce a novel ex vivo human skin barrier repair model. To develop this, we removed the upper layer of the skin, the stratum corneum (SC) by a reproducible cyanoacrylate stripping technique.

The project investigates the implementation of policies and practices related to reconciliation and the strengthening of government capacity in the Odesa and Kharkiv regions of Ukraine.

On the 2nd of September Jiyan Qiao successfully defended a doctoral thesis and graduated.

In Freedom on the Offensive, William Michael Schmidli illuminates how the Reagan administration's embrace of democracy promotion was a defining development in US foreign relations in the late twentieth century.

The eighth issue of the JLGC explores the diverse and interdisciplinary research on our multifaceted relationship with animals which is currently taking place, re-examining the relationship between humans and animals, and the definitions involved.

A new Special Issue with Transnational Legal Theory edited by Jelena Belic, Matthew Canfield, Henning Lahmann, Rachel Griffin, and Barrie Sander, brings together a collective of perspectives to unpack the promise and perils of human rights as a vocabulary for governing digital platforms.

On 21 Januari 2020, Patrick van Berlo defended his thesis 'Human Rights Elephants in an Era of Globalisation: Commodification, Crimmigration, and Human Rights in Confinement'. The doctoral research was supervised by Prof. J.P. van der Leun and Prof. M.A.H. van der Woude.

Identifying natural plant-associated bacteria that provide targeted inhibition of pathogens through the production of antimicrobial peptides.