387 search results for “infection” in the Public website
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Marlies ReindersFaculty of Medicine
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Thorbald van HallFaculty of Medicine
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Jannie Keyser-BorstFaculty of Medicine
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Paul ParrenFaculty of Medicine
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Karin de VisserFaculty of Medicine
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Louis KroesFaculty of Medicine
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Viral Infections Research in a Data Driven Era: Infectious disease surveillance and real-world causal inference
PhD defence
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Advancing host-directed therapy for Mycobacterium avium infection: identification of drug candidates and potential host targets
PhD defence
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Whole genome sequencing and contact screening in the surveillance and infection control of methicillin and borderline oxacillin resistant Staphylococcus
PhD defence
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Overview
The Division of Systems Pharmacology and Pharmacy (SPP) aims to develop precision medicine approaches to characterise and predict variation in treatment response and enhance translational drug development strategies.
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Bioprinting human tissues for drug testing
Bioprinters that enable scientists to engineer complex tissues and organs. It sounds like science-fiction, but not for the scientists of the Alireza Mashaghi lab at the Leiden Academic Centre for Drug Research. The lab has recently been equipped with two state-of-the-art bioprinters: BioX and LumenX+.…
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Disrupted movement makes macrophages more lethal to tuberculosis bacteria
Macrophages – the front line of our immune system – protect us from infections. But in the case of the tuberculosis bacteria, this often goes wrong. The group of Annemarie Meijer from the Leiden Institute of Biology has now discovered that macrophages in zebrafish are better able to eliminate tuberculosis…
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New insights for improved pertussis vaccines - Press release -
Researchers in Bilthoven, The Netherlands, have recently unraveled the defense against whooping cough bacteria in unprecedented detail. The outcome of the project, conducted at Intravacc (Institute for Translational Vaccinology) in Bilthoven, provides opportunities for a new approach in the development…
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Why COVID-19 caused a pandemic (whereas other coronaviruses did not)
Epithelial cells play a crucial role in the lungs. PhD student Ying Wang researched the effects of cigarette smoke and viruses such as COVID-19 on these epithelial cells. ‘We hope to reduce the risk of pandemics in the future.’
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Are bacteriophages the new antibiotics?
Bacteriophages, viruses that infect bacteria, may be used as an alternative treatment option when antibiotics fail. Leiden researchers have studied the structure and function of a novel bacteriophage that could be used to treat one of the WHO bacterial strains of concern where new treatments are urgently…
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Determining the kinetic profile of ENT1 inhibitors
Supervisor: Anna Vlachodimou
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Key publications
Key publications of the Quantitative Pharmacology group
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Leiden University Medical Center
The Leiden University Medical Center (LUMC) is committed to improving healthcare and the health of individuals. The LUMC staff put this mission into practice on a daily basis with their leading research, cutting-edge teaching and optimal, innovative healthcare.
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Leiden Spinoza and Stevin Prize laureates
Of the 111 Spinoza Prizes that have been awarded since 1995, 28 have gone to researchers from Leiden University.
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Stem cells suppress rejection in organ transplants
Treatment with special stem cells seems to be a good option for suppressing the immune system in organ transplants. Researchers are trying to learn from processes that take place in the human body during pregnancy.
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Health and disease
Bone research provides plenty of detailed data about the health of a person or a group. This data is not only used to reconstruct the past but also to fight disease today.
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How protein modifications cooperate to repair DNA
How do protein modifications work together to repair DNA, and what can we learn about these interactions to better understand disease?
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Why Biomedical Sciences at Leiden University?
The Biomedical Sciences Master programme in Leiden will help to deepen and broaden your understanding of human health and disease. We provide you with a challenging and flexible programme in a personalized environment.
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Malaria researchers from all parts of the world in Leiden
Researchers from all parts of the world will be in Leiden from 2 to 4 May for a major malaria conference. The Leiden University Medical Center (LUMC) is organising a two-day workshop on how vaccines can be tested safely in humans.
- Publication highlights
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First clinical trial with genetically modified malaria vaccine completed
In an innovative study, Radboudumc and LUMC jointly tested a candidate vaccine based on a genetically weakened malaria parasite. The results of this clinical trial, published in Science Translational Medicine, show that the vaccine is safe and elicits a defense response against a malaria infection.
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Koos van der HoevenFaculty of Medicine
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Jaap Jan ZwagingaFaculty of Medicine
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Frits KoningFaculty of Medicine
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Thomas OttenhoffFaculty of Medicine
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Fijs van LeeuwenFaculty of Medicine
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Jan van LithFaculty of Medicine
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Willem FibbeFaculty of Medicine
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Bart van HoekFaculty of Medicine
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Annette van der Helm-van MilFaculty of Medicine
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Amir ZadpoorFaculty of Medicine
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Reinaldus ToesFaculty of Medicine
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Mark de BoerFaculty of Medicine
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Manfred WuhrerFaculty of Medicine
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Frank StaalFaculty of Medicine
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Thomas HuizingaFaculty of Medicine
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Henricus VerspagetFaculty of Medicine
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Sugarcoating the search for a new vaccine
A vaccine based on sugar coats does have the potential to combat a multi-resistant staphylococcus. That is what Jeroen Codée and his colleagues from Utrecht state in Nature. In doing so, they are contradicting the earlier conclusions of German colleagues.
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Awards and Grants 2024
On this page you will find an overview of awards and prizes granted to our staff and students in 2024, as well as special appointments at Leiden University and other institutions.
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White blood cells in transparent embryos
Leiden molecular cell biologists in the research group of Annemarie Meijer have discovered novel early macrophage-specific genes in zebrafish, including a signal transducer pivotal for the migration of macrophages in the innate immune response to bacterial infection. Their findings were published on…
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Major Leiden symposium on TB bacteria
More than 1.3 million people worldwide die of tuberculosis (TB) each year, making research on its prevention and control essential. Researchers from various disciplines in Leiden are studying TB. A symposium on 24 March will highlight different activities in the hope of boosting nationwide collabora…
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Close contact between women and dogs in prehistoric times
Close contact between women and dogs in prehistoric times Women and dogs were in close contact in the neolithic age of hunters-fishers-gatherers. This has been suggested by Leiden osteoarchaeologist Dr Andrea Waters-Rist and fellow researchers who have studied a tiny biological fossil. The fossil was…
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Africa reconsidered
If you follow the western media, you are likely to think of ‘Africa’ as the continent of origin of desperate migrants, a continent of hunger and disease and a breeding ground for international terrorism. But if you want to see the bigger picture, you should look no further than the African Studies scholars…
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Statement on ransomware incident at NVIC
In the following statement we would like to inform you of a ransomware incident at the Netherlands-Flemish Institute in Cairo (NVIC) in which your personal information might have been involved. The University of Leiden administrates this institute. Related to the transition to working from home as…
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The immune system: step it up or slow it down?
When foreign matter enters our body, our immune system has to make a choice whether or not to go on the attack. There are times when the system goes wrong, and we end up with an illness or an allergic reaction. Researchers at LUMC are trying to steer the immune system. The dossier on Immunity, Infection…