391 search results for “infection” in the Public website
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Joan Hendrik Veelken -
Marlies Reinders -
Thorbald van Hall -
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Jannie Keyser-Borst -
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Karin de Visser -
Louis Kroes -
Viral Infections Research in a Data Driven Era: Infectious disease surveillance and real-world causal inference
PhD defence
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Advancing host-directed therapy for Mycobacterium avium infection: identification of drug candidates and potential host targets
PhD defence
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Whole genome sequencing and contact screening in the surveillance and infection control of methicillin and borderline oxacillin resistant Staphylococcus
PhD defence
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Overview
The Division of Systems Pharmacology and Pharmacy (SPP) aims to develop precision medicine approaches to characterise and predict variation in treatment response and enhance translational drug development strategies.
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Bioprinting human tissues for drug testing
Bioprinters that enable scientists to engineer complex tissues and organs. It sounds like science-fiction, but not for the scientists of the Alireza Mashaghi lab at the Leiden Academic Centre for Drug Research. The lab has recently been equipped with two state-of-the-art bioprinters: BioX and LumenX+.…
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Disrupted movement makes macrophages more lethal to tuberculosis bacteria
Macrophages – the front line of our immune system – protect us from infections. But in the case of the tuberculosis bacteria, this often goes wrong. The group of Annemarie Meijer from the Leiden Institute of Biology has now discovered that macrophages in zebrafish are better able to eliminate tuberculosis…
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New insights for improved pertussis vaccines - Press release -
Researchers in Bilthoven, The Netherlands, have recently unraveled the defense against whooping cough bacteria in unprecedented detail. The outcome of the project, conducted at Intravacc (Institute for Translational Vaccinology) in Bilthoven, provides opportunities for a new approach in the development…
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Why COVID-19 caused a pandemic (whereas other coronaviruses did not)
Epithelial cells play a crucial role in the lungs. PhD student Ying Wang researched the effects of cigarette smoke and viruses such as COVID-19 on these epithelial cells. ‘We hope to reduce the risk of pandemics in the future.’
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Determining the kinetic profile of ENT1 inhibitors
Supervisor: Anna Vlachodimou
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Key publications
Key publications of the Quantitative Pharmacology group
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Leiden University Medical Center
The Leiden University Medical Center (LUMC) is committed to improving healthcare and the health of individuals. The LUMC staff put this mission into practice on a daily basis with their leading research, cutting-edge teaching and optimal, innovative healthcare.
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Stem cells suppress rejection in organ transplants
Treatment with special stem cells seems to be a good option for suppressing the immune system in organ transplants. Researchers are trying to learn from processes that take place in the human body during pregnancy.
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Health and disease
Bone research provides plenty of detailed data about the health of a person or a group. This data is not only used to reconstruct the past but also to fight disease today.
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How protein modifications cooperate to repair DNA
How do protein modifications work together to repair DNA, and what can we learn about these interactions to better understand disease?
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Why Biomedical Sciences at Leiden University?
The Biomedical Sciences Master programme in Leiden will help to deepen and broaden your understanding of human health and disease. We provide you with a challenging and flexible programme in a personalized environment.
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Leiden Spinoza and Stevin Prize laureates
Of the Spinoza Prizes that have been awarded since 1995, 29 have gone to researchers from Leiden University.
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Are bacteriophages the new antibiotics?
Bacteriophages, viruses that infect bacteria, may be used as an alternative treatment option when antibiotics fail. Leiden researchers have studied the structure and function of a novel bacteriophage that could be used to treat one of the WHO bacterial strains of concern where new treatments are urgently…
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Malaria researchers from all parts of the world in Leiden
Researchers from all parts of the world will be in Leiden from 2 to 4 May for a major malaria conference. The Leiden University Medical Center (LUMC) is organising a two-day workshop on how vaccines can be tested safely in humans.
- Publication highlights
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First clinical trial with genetically modified malaria vaccine completed
In an innovative study, Radboudumc and LUMC jointly tested a candidate vaccine based on a genetically weakened malaria parasite. The results of this clinical trial, published in Science Translational Medicine, show that the vaccine is safe and elicits a defense response against a malaria infection.
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Sugarcoating the search for a new vaccine
A vaccine based on sugar coats does have the potential to combat a multi-resistant staphylococcus. That is what Jeroen Codée and his colleagues from Utrecht state in Nature. In doing so, they are contradicting the earlier conclusions of German colleagues.
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Reinaldus Toes -
Mark de Boer -
Amir Zadpoor -
Annette van der Helm-van Mil -
Frits Koning -
Thomas Ottenhoff -
Jan van Lith -
Frank Staal -
Willem Fibbe -
Bart van Hoek -
Jaap Jan Zwaginga -
Fijs van Leeuwen -
Margreet Kloppenburg -
Manfred Wuhrer -
Koos van der Hoeven -
Thomas Huizinga -
Henricus Verspaget -
Awards and Grants 2024
On this page you will find an overview of awards and prizes granted to our staff and students in 2024, as well as special appointments at Leiden University and other institutions.
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White blood cells in transparent embryos
Leiden molecular cell biologists in the research group of Annemarie Meijer have discovered novel early macrophage-specific genes in zebrafish, including a signal transducer pivotal for the migration of macrophages in the innate immune response to bacterial infection. Their findings were published on…
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Major Leiden symposium on TB bacteria
More than 1.3 million people worldwide die of tuberculosis (TB) each year, making research on its prevention and control essential. Researchers from various disciplines in Leiden are studying TB. A symposium on 24 March will highlight different activities in the hope of boosting nationwide collabora…
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Close contact between women and dogs in prehistoric times
Close contact between women and dogs in prehistoric times Women and dogs were in close contact in the neolithic age of hunters-fishers-gatherers. This has been suggested by Leiden osteoarchaeologist Dr Andrea Waters-Rist and fellow researchers who have studied a tiny biological fossil. The fossil was…