Promotor: F.H.J. Redig, Co-Promotor: W.T.F. den Hollander

Nicolas Navarre is a PhD student in Industrial Ecology whose work is grounded in evaluating the impact of innovations within larger systems.

The way organisms develop from the initial single-cellular state to a complex final assembly like the human body, and how the final body is maintained throughout life, is one of the greatest mysteries and it’s understanding one of the biggest scientific challenges.

This is the first full-scale reference grammar of Classical Greek in English in a century.

Ferritin is a spherical metalloprotein, capable of storing and releasing iron in a controllable way. It is composed of a protein shell of about 12 nm and within its cavity, iron is stored in a mineral form.

DNA carries various forms of information. Out of these forms of information the most well-known is classical genetic information.

Quantum hardware comes with a different computing paradigm and new ways to tackle applications. Much effort has to be put into understanding how to leverage this technology to give real-world advantages in areas of interest for industries such as combinatorial optimization or machine learning.

Despite being the object of intense study, embryonic development has been difficult to model due to a number of reasons. First, complex tissues can be comprised of many cell types, of which we probably only know a subset.

This dissertation combines the use of defined microenvironments, high-resolution fluorescence microscopy, and time-resolved analysis, to study intracellular and cellular motility.

This study looks at the diverse phonological systems found within Central Chadic, and reconstructs the phonological system of their ancestor language.

The ability to count is a property not often attributed to materials, despite the abundance of memory in materials. Regardless of how a material stores information, it is often difficult to retrieve exactly ‘what’ a material remembers.

This thesis describes how to scale down concepts of macroscopic mechanical metamaterials to the thermal scale using a system of flexibly-linked colloids.

The aim of the project is the development of polypept(o)ide-based delivery systems to use siRNA as systemic applicated therapeutic agent against e.g. solid tumors

On 25 January 2018 Yannick van den Brink defended his doctoral thesis titled ‘Voorlopige hechtenis in het Nederlands jeugdstrafrecht’ (‘Pre-trial detention in the Dutch juvenile justice system’). The doctoral research is supervised by Professor Ton Liefaard and Professor Mariëlle Bruning.

We are developing biology-driven platforms to measure metabolites based on liquid chromatography-mass spectrometry (LC-MS), gas chromatography-MS (GC-MS), and capillary electrophoresis-MS (CE-MS).

On 24 September 2020, Bernardo Ribeiro de Almeida defended his thesis 'Building land tenure systems: the political, legal, and institutional struggles of Timor-Leste'. The doctoral research was supervised by Prof. A.W. Bedner. Co-supervisor was Dr. C.I.M. Jacobs.

Shana Hepping is a PhD researcher at the Institute of Public Administration.

Policy Note Insecurity in Burkina Faso – beyond conflict minerals: The complex links between artisanal gold mining and violence

Inflammatory skin diseases such as psoriasis and atopic dermatitis can severely impact both the physical and social aspect of a patient’s life. Aberrant inflammatory responses are thought to be a major causative factor in these disorders, but an abundance of different factors contribute to the development…

On 17 December 2018, Dejian Kong defended his thesis 'Civil Liability for Damage caused by Global Navigation Satellite System'. The doctoral research was supervised by Prof. dr. P.M.J. Mendes de Leon.

Generations of Leiden students and academics have done archaeological research into the early medieval history of Oegstgeest. This makes this old settlement one of the best-documented sites from that era. In a new book, Leiden researchers take stock.

This thesis focuses on two processes involved in fighting infections: metabolism and immune cell motility and navigation.

Intelligence of the crowd, or in other words, intelligence of a large, random collective, exists mostly in social media platforms such as twitter. The collective does not comprise (at least not necessarily) experts on crises, just regular people mostly. Nevertheless, there is valuable intelligence to…

The mechanism of the electrochemical reduction of dioxygen by a mononuclear pyridylalkylamine copper complex was investigated (see picture). It was shown that in neutral aqueous solution dioxygen undergoes stepwise reduction, wherein hydrogen peroxide plays a key role. The rate constants determined…

We study the structure, dynamics and physics of complex networks emerging from the intricate interconnectedness of the constituents of large systems.

When foreign matter enters our body, our immune system has to make a choice whether or not to go on the attack. There are times when the system goes wrong, and we end up with an illness or an allergic reaction. Researchers at LUMC are trying to steer the immune system. The dossier on Immunity, Infection…

How can pupils and students learn to get a grip on complex 'swamp situations'? Inaugural lecture in abbreviated form held by prof.dr.ir. Fred Janssen on the acceptance of the post of professor of science education at Leiden University on 19 June 2017.

You can ask virtual assistant Siri about the weather, but you can’t have a real conversation with it yet. You can’t refer to anything that’s been said before, or ask the system why it says what it says. Stephan Raaijmakers, Professor by Special Appointment from TNO, hopes to change this.

‘It has never been so easy to set up a Studium Generale series.’ With these words Tilman Grünewald thanked speaker Frank den Hollander, who kicked off the Studium Generale series on complex networks on Monday 20 February.

The research in my group addresses a range of topics related to quantum many-body physics.

The information below concerns courses that our group teaches in Leiden. 

How does the development of digital technologies impact society, and law/regulation within that society?

Promotores: W.T. de Groot, M. Tchuenté, Co-promotor: J.P. Cheylan

Using artificial intelligence is more complicated for the government than for companies. Bram Klievink, Professor of Public Administration, aims to identify the problems and find solutions.

Xinrong Ma defended her thesis on 13 February 2018

The project investigates the changing local context of crime dynamics and the responses by selected international organizations and national governments. It places a major emphasis on security management at the trans-national level by investigating intra-regional security cooperation between Latin America,…

How do young adults find their way in an increasingly complex society? In Leiden, as part of the GUTS project, we study how brain development and self-regulation play a role in this process.

This thesis consists of two main parts. The first part (Chapters 2 and 3) deals with a class of Markov process called Quasi-Skipfree (QSF) processes.

Lodewijk Petram, author of the book 'The World's First Stock Exchange', discussed the rise of the Amsterdam stock exchange in the 17th century in the ninth Hazelhoff Guest Lecture.

In December 2024, the book Redressing Fundamental Rights Violations by the EU: The Promise of the ‘Complete System of Remedies', edited by Melanie Fink, was published fully open access with Cambridge University Press. The EU prides itself on having created a legal system that puts the individual at…

Growth and development affect the metabolism of drugs administered to neonates, infants, and children.

The focus of this thesis is how stars like our Sun and planets like Jupiter, Saturn, and Earth are formed.

Analysis of drug adversity

The upscaling of Life Cycle Assessment (LCA) data is recognized as one of the main challenges in the ex-ante LCA of emerging technologies. This challenge arises since industrial-scale system specifications for these technologies are unknown and industrial data is lacking.

Students with learning problems experience difficulties in reading, writing, and content-area learning into and throughout their secondary-school years