Promotor: J. N. Kok, Co-promotor: A. J. Knobbe

The book ‘Bestrijdingsmiddelen en Milieu' gives a transparent overview of facts and figures concerning pesticide use in the Netherlands and the impact of pesticides on the environment.

This dissertation is organised into three parts, each addressing a distinct research area related to Gibbs measures.

Promotor: G.P. van Wezel

The four possible segments A, T, C and G that link together to form DNA molecules, and with their ordering encode genetic information, are not only different in name, but also in their physical and chemical properties.

Promotores: Bas Edixhoven, Guy Henniart

Promotores: P. Stevenhagen, E. Fouvry (Univeriste Paris Saclay)

Promotores: S.F. Portegies Zwart, E. M. Rossi

The aim of the research presented in this thesis was to develop new methods forchallenging systems in liquid-state NMR using paramagnetic effects generated by thetwo-armed probe CLaNP-5.

The main subject of this thesis is the design and synthesis of paramagnetic molecules for protein studies with NMR and EPR spectroscopy.

In some condensed matter systems, such as the surface of a 3D topological insulator, the electrons are effectively massless and we must necessarily use the massless Dirac equation to describe them.

In this thesis we classify the pairs (p,G), where p is a prime number and G is a finite p-group possessing an intense automorphism, i.e. an automorphism that sends each subgroup of G to a G-conjugate, that is non-trivial and whose order is coprime to p.

In oktober 1740 voltrok zich in Batavia een drama waarvan de overzeese wereld een aantal maanden later met ontsteltenis kennisnam. Als reactie op een Chinese volksopstand tegen het VOC-bestuur richtten de Europese burgers van de stad samen met de matrozen van de vloot een verschrikkelijke slachting…

Promotor: Prof.dr. R. Verpoorte, Co-Promotor: Dr. Young Hae Choi

To an algebraic curve C over the complex numbers one can associate a non-negative integer g, the genus, as a measure of its complexity.

Mining time series is a machine learning subfield that focuses on a particular data structure, where variables are measured over (short or long) periods of time.

This PhD thesis concerns the topic of arithmetic geometry. We address three different questions and each of the questions in some way is about counting how big some set is or can be.

Promotor: H.W. Lenstra

Bicarbonate buffer is largely found in nature due to its ability to regulate pH variations around neutral values. As the pH changes, so does the speciation of the buffer.

There is concern about the threat that nanoplastics (NPs) may pose to both wildlife and humans. This thesis explores the mechanisms of toxicity of polystyrene nanoparticles (PS-NPs) in chicken embryo.

Promotor: J.N. Kok, P.E. Slagboom Co-promotor: J.F.J. Laros

Promotores: W. Th. F. den Hollander, M.O. Heydenreich

This thesis seeks to combine two different research topics; Multi-Objective Optimization and Complex Network Analysis.

Promotores: K.J. Batenburg, B. Koren

Low-carbon (LE) technologies have a significant potential to reduce the total carbon emissions in China.

Promotor: Thomas Hankemeier, Co-promotores: Heiko van der Linden, Paul Vulto

This thesis describes the design and development of subunit‐selective inhibitors of particular catalytically active subunits of human constitutive proteasomes and immunoproteasomes.

Drug-induced liver injury (DILI) is one of the main reasons for drug attrition during pre-clinical and clinical phases of drug development as well as for drug withdrawal post-marketing.

Promotores: R. Cramer, A.K. Lenstra, Co-Promotor: B.M.M. de Weger

Promotor: P.D. Grünwald

Promotor: G.R. de Snoo, Co-promotor: C.J.M. Muster

The research in this thesis is focused on tomographic reconstruction based on two imaging modalities in electron microscopy.

This dissertation presents new cryptographic protocols, which can be divided into two families.

This monograph focuses on clustering of objects in high-dimensional data, given the restriction that the objects do not cluster on all the attributes, not even on a single subset of attributes, but often on different subsets of attributes in the data.

The ongoing increase in antimicrobial resistance combined with the low discovery of novel antibiotics is a serious threat to our health care.

Promotor: Prof.dr. F.S. de Boer, Co-promotor: D. Clarke

Promotores: C. J. ten Cate; M. A. Ainslie. Co-promotor: W. Slabbekoorn

Inverse problems are problems where we want to estimate the values of certain parameters of a system given observations of the system. Such problems occur in several areas of science and engineering. Inverse problems are often ill-posed, which means that the observations of the system do not uniquely…

Promotor: Prof.dr. P.G.L Klinkhamer, Co-promotor: K. Vrieling

Promotor: Bas Edixhoven, Promotor: Qing Liu

This dissertation explores new chemical strategies for the synthesis of self-adjuvanting peptide conjugates and immunomodulatory ligands aimed at targeted activation of the immune system.

Promotores: H.W. Lenstra, K. Belabas (University of Bordeaux)

The global agri-food system plays a critical role in food security and environmental issues.

In the last decades, activity-based protein profiling (ABPP) has emerged as a powerful chemical tool that may aid the ever-challenging drug discovery process.

Promotores: P. Stevenhagen, L. van Geemen (Università degli studi di Milano), Co-Supervisor: Ronald M. van Luijk

Nieuw op de campus: peukenstemmers. Heb jij ze al gespot? Drop hieronder jouw briljante, non-scientific vraag en wie weet wordt die de volgende butt-kicker!

Promotor: Peter Stevenhagen

To improve cancer treatments, personalized medicine approaches have aimed to identify exactly which mutations are driving tumor development in a given patient and specifically target these mutations using precision therapies.

As a virtually inexhaustible source, solar energy plays a major role in future global energy scenarios.

Promotores: H.W. Lenstra, A. Lucchini