Balsaminaceae is a diverse plant family characterized by a huge floral morphological diversity.

Promotor: J.G.E.M. Fraaije, Co-Promotor: A. Kros

Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…

Promotor: J.M. van Ruitenbeek, Co-Promotor: S.J. van der Molen

Promotor: A.P. IJzerman

This dissertation presents the results of the importance of creativity for ICT-students of Dutch universities of applied sciences (in Dutch: hogescholen), and the functioning of training courses that aim to promote creative abilities is highlighted.

Several single-stranded RNA viruses make use of Xrn1-resistant RNAs in their 3’ untranslated regions of their genome RNAs in order to increase their pathogenicity.

Streptomyces present a valuable platform for natural product discovery. Lugdunomycin is a novel angucycline-derived polyketide from Streptomyces sp QL37, with unprecedented skeleton and antimicrobial activity.

Promotor: Prof.dr. T. Hankemeier, Prof.dr. J.C.T. Eijkel (Twente University)

This research delves into a region of space known as the interstellar medium (ISM), which is essentially the area between the stars filled with gas and dust.

The plant hormone auxin regulates plant growth and development through polar cell-to-cell transport-generated maxima and minima. PIN FORMED (PIN) auxin efflux carriers determine the direction of this auxin flow through their asymmetric placement on the plasma membrane (PM).

Promotor: A. Kros

One of the key discoveries in exoplanet research over the past decade is the abundance of small planets in our Milky Way. Despite their high numbers, our understanding of their atmospheres remains limited, and it is unknown if they possess atmospheres at all.

Membrane fusion is a vital process in living organisms and is mediated by zipper-like proteins.

Pharmaceutical companies, governments and the general public have become increasingly aware that animal models used in drug testing lack vital aspects to serve as an accurate representation of human biology. As models of the human body should become more physiologically relevant, animal models no longer…

Promotor: Prof.dr. M.L. van Hecke

A remarkable population of short period transiting rocky exoplanets with equilibrium temperatures on the order of 2,000 K has recently been discovered.

Animal diet studies are critical for understanding ecological processes such as trophic interactions, energy flow, and nutrient cycling. By examining what animals consume, ecologists gain insights into species specialization, predator-prey relationships, and ecosystem management.

My work focuses on a class of astronomical objects called protoplanetary disks.

In condensed matter systems electron-electron interactions, negligible in everyday metals, can dramatically alter the electronic behavior of the system. Examples of such altered behavior include high-temperature superconductivity and modulation of the electron density.

Ontdek de cursus Communicating in Legal English van de Leiden Law Academy en verbeter uw juridisch Engelse vaardigheden. Lees hier meer!

De onderzoeksgroep Terrorism and Political Violence van de Universiteit Leiden bestudeert de oorzaken van radicalisering, de tactieken van extremistische groeperingen, en de effectiviteit van anti-terrorismebeleid. We onderzoeken ook de rol van media en de invloed van postkoloniale erfenissen in de…

The thesis describes experimental steps towards reduction of friction on the macroscopic scale by scenarios of thermo- and superlubricity well-known on the nanoscale.

Electrons in a crystal lattice have properties that may differ from those of a free electron in vacuum.

Promotores: A.P. IJzerman, H.W.T. van Vlijmen

Studievoorlichting

Studievoorlichting

Studievoorlichting

Studievoorlichting

Studievoorlichting

In this thesis an activity-based probe was discovered that could visualize the activity of PLAATs. With an optimized gel-based ABPP assay in hand, screening of a compound library led to the discovery of alpha-ketoamides as a hit for PLAAT3.

In order to gain a better insight into the basis of the rapid jasmonic acid (JA)-mediated stress response, an integrated approach using a targeted high-resolution mass spectrometry-based (HRMS) platform, was conducted to monitor the metabolism of JA using the model system of cell suspension cultures…

Promotores: Prof.dr. F. van Lunteren, Prof.dr. F.S. Gaastra

Kunst en vrije tijd, Kunst en vrije tijd

Studievoorlichting

Traditional hypothesis testing requires researchers to set a fixed sample size in advance. After collecting data, the test determines whether to reject the null hypothesis.

Promotor: T. Hankemeier, Co-promotor: R.J. Vreeken

Kunst en vrije tijd, Kunst en vrije tijd

Studievoorlichting

Studievoorlichting

In this thesis chemical and physical processes in the ice mantles on interstellar dust grains are studied.

Carbohydrates are present on the surface of bacteria making them suitable antigen candidates for vaccine development. This thesis deals with the synthesis of two carbohydrate-based components; the capsular polisaccharide of S. aureus type 5 and teichoic acids from staphilococci and enterococci speci…

In this PhD study, I aim to deepen our understanding of the influence of major mycorrhizal types, namely arbuscular mycorrhizae (AM) and ectomycorrhizae (EM), on the global soil carbon cycle and their potential distribution changes under future environmental shifts.

Like a mixture of oil and water, lipid membranes separate into two liquid phases.

This dissertation aims to advance understanding of amoeboid single cell migration under the influence of changing physicochemical environmental properties. The particular focus is on the relatively unknown influence of differing physical properties in the extracellular environment, such as the migratory…

Anthropogenic change is reshaping ecological systems, raising concerns about increasing transmission of infectious diseases. Among these, mosquito-borne diseases may be particularly sensitive to environmental change, as their transmission depends on vector populations.

CMLCA is a software tool that supports the technical steps of the Life Cycle Assessment. The focus of the program is on advanced computational aspects of life cycle inventory calculations.