Hoe kunnen we onze maatschappij zo inrichten dat de wereld leefbaar blijft voor onszelf en al het andere leven om ons heen? Aan dat vraagstuk werken Leidse wetenschappers samen vanuit allerlei disciplines, van biologie tot datawetenschap en van milieueconomie tot archeologie.

Dit doctoraatsproject onderzoekt voornamelijk op welke manier (d.w.z. serieel, parallel of op een andere manier) de parser het Mandarijn-Chinees verwerkt. Daarnaast wordt onderzocht of er specifieke taalkundige kenmerken zijn die de decodering van het Mandarijn-Chinees bepalen en die verschillen van…

Promotor: G.P. van Wezel

Heterogeneous catalysis is essential to many industrial applications. These catalysts are often comprised of supported nanoparticles, which contain various different surface sites.

Transplantation of labial salivary glands to the eyelids for patients with dry eye appears to give excellent results clinically.

The development of new environmentally sound technologies is seen as a key route towards achieving sustainability.

The department of Industrial Ecology is dealing with research into the development of tools for decision making on sustainable production and consumption.

Chemical-induced organ toxicity is a major concern in the development and use of chemicals, including drugs, pesticides, industrial chemicals and cosmetics. In the last decades, the onset and progression of chemical-induced organ toxicity has been linked amongst others to perturbation of mitochondri…

Promotores: F.H. van Lunteren, F.P. Israel

Low-carbon (LE) technologies have a significant potential to reduce the total carbon emissions in China.

Pectin is a plant cell wall polysaccharide made of mainly D-galacturonic acid (GA) subunits. The potency of the filamentous fungus Aspergillus niger to naturally secrete high amounts of pectinases to degrade pectin has been utilized for the industrial production of pectinases.

Electrocatalysis allows for storing electricity or converting it into chemical bonds, producing chemical building blocks and fuels using renewable resources.

LCA has become an important method to study environmental impacts of human activities. Still, there are several methodological issues in LCA that can adversely affect the results reliability.

Promotor: Prof.dr. J.N. Kok

According to the amyloid cascade hypothesis, accumulation of beta-amyloid (Aβ) peptides initiates the pathological cascade in Alzheimer's disease (AD).

In this thesis it is posed that the central object of preference discovery is a co-creative process in which the Other can be represented by a machine. It explores efficient methods to enhance introverted intuition using extraverted intuition's communication lines.

This thesis discusses the physical and chemical processes than influence the composition of forming planets.

Promotores: F.H.J. Redig, W.T.F. den Hollander

Promotor: Prof.dr. E. F. van Dishoeck

Human language is constantly evolving with its linguistic structure being shaped by language users at both individual and population levels. Focusing on the interplay between processes of language acquisition and communicative need in shaping human languages, this thesis introduces a novel computational…

Promotor: Richard D. Gill

Tin electrodeposition applications have rapidly evolved in the past 25 years.

This dissertation focuses on developing new mathematical and statistical methods to properly represent time-varying covariates and model them within the context of time-to-event analysis.

Promotor: Prof.dr. E.F. van Dishoeck, Co-Promotor: G.J. Herczeg

Studying the impact of urbanisation on the respiratory health of past Dutch populations (1200-1850 CE).

From surface science towards industrial practice using high-pressure scanning tunneling microscopy.

Wil jij de beste redenen weten waarom je een master aan de Universiteit Leiden moet volgen? Of hoe het is om te studeren in Leiden of Den Haag? Onze studenten vertellen je over hun studie aan de Universiteit Leiden.

Machine Learning is becoming a more and more substantial technology for industry.

Promotor: F.S. de Boer, Co-promotor: M.M. Bonsangue

In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.

Hoe is het om mee te doen aan het Leiden Leadership Programme? Alumni delen hun ervaringen: 'Je leert dingen over leiderschap en kan die ook meteen in de praktijk brengen.'

Wil jij de beste redenen weten waarom je een master aan de Universiteit Leiden moet volgen? Of hoe het is om te studeren in Leiden of Den Haag? Onze studenten vertellen je over hun studie aan de Universiteit Leiden.

Ben jij nieuwsgierig naar hoe wetenschap en technologie bijdragen aan een duurzame en innovatieve toekomst? Bij de Universiteit Leiden onderzoek je de wereld van data, natuurwetten en levende systemen. Van wiskunde tot kunstmatige intelligentie, van klimaatvraagstukken tot hightech innovaties: je leert…

Ben jij nieuwsgierig naar hoe wetenschap en technologie bijdragen aan een duurzame en innovatieve toekomst? Bij de Universiteit Leiden onderzoek je de wereld van data, natuurwetten en levende systemen. Van wiskunde tot kunstmatige intelligentie, van klimaatvraagstukken tot hightech innovaties: je leert…

Traditional hypothesis testing requires researchers to set a fixed sample size in advance. After collecting data, the test determines whether to reject the null hypothesis.

Het onderzoek in dit proefschrift kijkt naar de rol van het locus ceuruleus - noradrenalinesysteem in verscheidene aspecten van menselijke cognitie, en de modulatie van de staat van het brein.

Promotores: Prof.dr. E.A.L. Biessen, Prof.dr. T.J.C. van Berkel

We developed the bitterling as a unique, well-studied model organism in the area of the evolutionary ecology of brood parasitism. The bitterling-mussel relationship, interspecific mussel host preference, and mussel gill structure are studied in detail, to help understand the developmental adaptation…

Membrane fusion is a vital process in living organisms and is mediated by zipper-like proteins.

The subject of this thesis, ‘Approach to Markov Operators on Spaces of Measures by Means of Equicontinuity’, combines an analytical and probabilistic approach to Markov operators.

Drug development is a time- and resource-consuming process that starts with the discovery and validation of a (protein) target that contributes to pathogenesis or disease progression.

Control of infectious diseases poses continuous challenges for human health.

The effective treatment of tuberculosis (TB) remains a major challenge to global health.

Promotor: T. Hankemeier, Co-promotor: T.H. Reijmers