For her bachelor’s thesis, Molecular Science and Technology student Madouc Bergers synthesized her own molecule that can inhibit the breakdown of sugars. Although most students do not even manage to make one building block, Madouc made three. Partly because of this, she has been nominated for the Science…

Leiden researchers have discovered an enzyme that helps bacteria feed on everyday plastics. This common enzyme could play a crucial role in future research and eventually in addressing the global plastic crisis. The study was published in Nature Communications.

A flu virus could cause a pandemic. And then we would be poorly armed because flu viruses are starting to become resistant to flu medications like Tamiflu. Chemist Merijn Vriends successfully worked on an improved version of such medications. He will be awarded his doctorate on September 12th.

From health to migration to climate: 25 interdisciplinary research and education initiatives received a Kiem grant in 2024.

Tuberculosis bacteria survive by hiding in our immune cells. In her PhD research, biologist Salomé Muñoz Sánchez explores how boosting the body’s own defenses might outsmart this deadly pathogen. Her work reveals two key proteins that help immune cells destroy the bacteria.

Biological chemist Nathaniel Martin and his team received an NWO grant to examine how blocking a specific enzyme in our body, NNMT, could be helpful in the treatment of some cancers. Trials with mice have been promising, and together with the Netherlands Cancer Institute, Martin wants to take the next…

How do fats and enzymes in the brain contribute to multiple sclerosis? In his PhD research, Daan van der Vliet combined chemistry and neuroscience to gain new insights into how brain disorders develop.

Leiden biologists have found a mutation in flour beetles that allows them to speed up their development. The study has been published in Nature Ecology and Evolution.

Why does a medicine work well for one person, but cause side effects in another? Research by Laura de Jong shows that it’s not just our DNA that matters – other medicines and illnesses can also affect how our bodies respond.

Destroying proteins from the Golgi apparatus of the cell in a controlled manner. That is the focus of chemist Marta Artola’s pioneering research. By developing a groundbreaking technology to target specific proteins in the Golgi, Artola aims to unlock new ways for drug development. For this ambitious…

A patent for what may be a potent, new antibiotic. And: a clear overview of promising approaches to overcome a crucial resistance tactic employed by bacteria. In the span of one week, two researchers from Leiden are receiving their PhDs, each of them on an important step in the battle against bacteria…

Leiden PhD candidate Jo-Anne Verschoor discovered that nearly twenty percent of the bacterial strains she studied could degrade plastic, though they needed some encouragement to do so. ‘Bacteria are just like people,’ says Verschoor. Her research was published in the journal Communications Biology,…

Professor of Fungal Genetics and Biotechnology Arthur Ram explains how fungi can help us be more sustainable.

Two consortia led by Leiden researchers have been awarded over one million euros by the Dutch Research Council and the Ministry of Health, Welfare and Sport to find solutions to antimicrobial resistance.

From medicines from snake venom to supercrops and the origin of words. Thirteen researchers from Leiden University will receive Open Competition XS grants from the Dutch Research Council (NWO).

Researchers at the Universities of Amsterdam (Uva) and Leiden together with the Netherlands Cancer Institute and Oncode Institute have received a €10,6 million ERC Synergy Grant to develop innovative therapeutic approaches to target glioblastoma. This is a deadly primary brain tumour for which no curing…

The challenge is considerable, but so is the satisfaction when it succeeds: creating complex sugar molecules that play a role in biology.

Cryogenic memories, antibiotic treatment for urinary tract infections and recycling plastic sustainably. These are the subjects of the three NWO-XS grants awarded to Leiden Science researchers.

Antibiotic resistance is an economic problem. Pharmaceutical companies cannot earn much from antibiotic research, so they do not invest in it. This makes it important that universities do so, says Ned Buijs.

Tracking mucus-eating bacteria, mapping the complexity of planetary nebulae and a signalling pathway in cancer. These three Leiden projects have been awarded Open Competition Science-M funding by the Dutch Research Council.

Martijn Verkuilen is the winner of the Unilever Research Prize 2022. By transferring DNA from a plant into yeast, he made the first move to produce a new drug for type 2 diabetes. He collected his prize in Wageningen on 24 November.

With the aid of physics and a minuscule magnet, researchers have discovered a new structure of telomeric DNA. Telomeres are sometimes seen as the key to living longer. They protect genes from damage but get a bit shorter each time a cell divides. If they become too short, the cell dies. The new discovery…

Bringing your drug candidates to patients is what many academic chemists dream about, but the road to this goal is long and bumpy. Now, Leiden small molecule nizubaglustat is ready for phase 3 clinical trials. This is thanks to a €132 million funding secured by the biotech spin-out Azafaros.

Three fundamental research projects at Leiden in physics, chemistry and medical science have received funding from the Dutch Research Council (NWO). They involve research on magnetic fields in the universe, the role of myeloid cells in cancer immunotherapy and the evolution of ancient proteins.

Lecture, Studium Generale

On 28 September the famous chemists Carolyn Bertozzi visited Leiden University to speak at the LED3 seminar. Just one week later, she was announced winner the 2022 Nobel Prize in Chemistry. Leiden chemists Sebastian Pomplun and Hermen Overkleeft are fan: ‘We are extremely honoured to have hosted this…

Lecture, Tuesday Talks: Science Insights

Ten scientists from Leiden University will receive a Starting Grant from the European Research Council. This will allow them to launch their own project, form their own research team and implement their best ideas.

On 11 March, pharmaceutical company Janssen received approval to launch its corona vaccine on the European market. This made Janssen the fourth company to be given the green light by the European Medicines Agency. As Lead of the Janssen Campus in the Netherlands, Biology alumnus Bart van Zijll Langhout…