Leiden theoretical physicists have proven that not only the genetic information in DNA determines who we are, but also DNA’s mechanics. Helmut Schiessel and his group simulated many DNA sequences and found a correlation between mechanical cues and the way DNA is folded. Publication in PLoS One.

On 16 June, Leiden University opens the MIGRADROME: a unique, seven-metre-long artificial river. Researchers will use it to study how light and sound affect migratory fish. ‘We’re recreating a real river, but under fully controlled conditions.’

Without electronics carrying out computational tasks our daily lives would look very different. Devices such as elevators, vending machines, turnstiles, washing machines and even traffic lights use a simple form of electronic computing to switch from state to state. But, what if power supply is not…

To give a better idea of the research at Leiden University, a new website has been launched that lists the University’s institutes together with the disciplines that they cover. But the institutes also work together intensively.

How many children are born with the help of a surrogate mother in the Netherlands, and which legal obstacles can arise? Through a new interdisciplinary study, researchers at Leiden University are attempting to provide clarity about surrogacy processes.

Microorganisms that temporarily ‘go to sleep’ play an important role in the evolution and survival of a population. Mathematician Shubhamoy Nandan conducted research on the effect of this characteristic called ‘dormancy’ in a novel mathematical model.

On 7 October, a court in Athens, Greece, convicted leaders of the far-right Golden Dawn party as directing a criminal organization. Marina Terkourafi, professor of Sociolinguistics, discusses the landmark ruling for the Leiden International Studies Blog.

This book describes the different approaches for drug delivery to the brain with an emphasis on the physiology of the blood-brain barrier (BBB) and the governing principles and concepts for drug delivery across the BBB

Have you considered including the Leiden University Fund in your will?

Leiden researchers have compiled information collected by scientists over the past 120 years into a database of plant-fungal interactions. This important biological data is now freely available for researchers and nature conservationists. Publication in New Phytologist.

Four Leiden researchers have been awarded Proof of Concept grants by the ERC. These grants, each worth 150,000 euros, help researchers translate the findings of previous ERC projects into innovative practical applications.

The High Troughput Microscopy Dutch Flagship Node that includes the Leiden Cell Observatory Screening platform is now officially ratified as a Euro-BioImaging (EuBI) Node Candidate

The logo of Leiden University, with letters as small as a bacterium. Researchers from LUMC and the Institute of Biology have created the smallest logo of our university ever produced. It is a piece of fun with a serious real-world application: the new microscope with which the logo was made allows scientists…

A piece of corrugated rubber can function as a simple computer, displaying memory and displaying the ability to count to two. Leiden physicists describe the computing rubber in the journal PNAS. ‘Simple materials can process information, and we want to find the principles behind that.’

A global biological study has provided the most direct evidence to date that humans, and specifically cities, are the drivers of evolutionary change on Earth. Leiden University, Naturalis and the Municipality of Leiden worked on and helped fund the study.

Museum De Lakenhal is displaying the smallest work of art in the world: a 3D-printed statue of Rembrandt van Rijn, made by sculptor Jeroen Spijker and researchers from Leiden University.

The underwater world around present-day Indonesia has changed greatly in recent centuries as a result of human activity. University lecturer Johannes Müller has been awarded an NWO XS grant to map the history of the Indonesian ecosystems.

Nanoplastics influence the behaviour of larval zebrafish, says new research by the Institute of Biology Leiden (IBL) and the Institute of Environmental Sciences (CML). The researchers observed that a certain type of nanoparticles leads to stress reactions in the sugar balance, resulting in hyperactivity…

Historical figures such as Columbus have returned to the centre of public debate. Much remains to be discovered about his legacy and current impact on our society. A new study shows the ecological footprint that the arrival of Europeans left in the Caribbean islands.

Two Leiden research projects that focus on increasing the biodiversity of Dutch production systems for food and ornamental horticulture have started thanks to funding from the Dutch Research Council's KIC research programme.

Through various initiatives, Leiden University is trying to make people aware of the importance of biodiversity: the cultivation of a wide variety of micro-organisms, animals and plant species. This is important because in the Netherlands biodiversity has declined from about 40 percent in 1900 to about…

Smart drug carriers, uneven cosmic expansion, and solar energy storage in molecules. These are the topics of three newly awarded NWO-XS grants to researchers at the Faculty of Science.

Fathers and mothers bring children up differently. Mothers are more likely to correct children for bad behaviour, for example. This is one of the findings of PhD research by Liesbeth Hallers-Haalboom. PhD defence 7 October.

Chemist Gerjan de Bruin has designed a method of slowing down the degradation process of proteins in cells. This may contribute to new cancer medicines with fewer side-effects. PhD defence on 1 June.

Bone remains that are thousands of years old are often too fragmented to be identified. PhD candidate Frido Welker is the first person to be able to distinguish human bones from one another on the basis of old proteins. PhD defence 18 May.

Violent conflicts and civil wars in Chad impede most rural households' access to food security, agricultural activities and access to essential services such as health care. In her dissertation, Nakar Djindil Syntyche denounces this issue. She obtained her PhD on 24 November.

Salma Balazadeh, Víctor Carrión, and Jos Raaijmakers, biologists at the Institute of Biology Leiden (IBL), have successfully applied for an NWO grant and got awarded 730.000 euros. The board of NWO Domain Applied and Engineering Sciences awarded funding for their project within the Open Technology Programme…

Acute stress seems to have a surprisingly positive effect on our health. Researcher Erin Faught received an NWO veni grant to find out why that is and how we can use that knowledge to our advantage. For her lab research, she uses a remarkable small animal to learn more about our own stress levels.

The expansion of European powers overseas brought Europeans into contact and conflict with the inhabitants of Africa, Asia, and the Americas. Historians of colonialism and post-colonial scholars have long argued that this encounter was crucial for the formation of European identity, which originated…

Mysterious protein fibers show up in the brain cells of people suffering from Alzheimer’s' disease and other neurodegenerative disorders. Leiden physicist Louise Jawerth has been awarded a Vidi grant to find out how these fibers form in the first place.

Studying languages enables you to unearth a lot of valuable information about humans: it reveals our history and explains cultural differences and it even illustrates the process of learning new information. The University is sharing its knowledge of and passion for languages in various new ways, including…

Former masterstudent Bio-Pharmaceutical Sciences Maddalena Centanni will be awarded the 2020 Arenberg Coimbra Prize for Erasmus Students. Centanni spent her six month Erasmus exchange at Uppsala Universiy in Sweden where she looked for ways to improve anti-cancer drug dosing.

Leiden chemists, together with colleagues at the University of York (UK) and Technion (Israel) have discovered a small, sugar-like molecule that maintains the integrity of tissue around a tumour during cancer. This molecule prevents tumour cells from spreading from the primary cancer site to colonise…

Researchers from the Leiden Institute of Chemistry show proof of principle that live-cell structural changes and metabolic processes can be followed in real time with NMR spectroscopy. They performed their study on photosynthetic green algae that are metabolically flexible and can sustain energy generation…

A new discovery proves that it matters which approach researchers take in analyzing large physical, social or biological systems that have a networked structure. Ever since the early 1900s, scientists have assumed each approach is equivalent. Now many results in statistical physics may no longer hold.…

Technological innovations such as home dialysis could significantly improve the quality of life and health of kidney patients. Professor Joris Rotmans therefore wants to continue pushing for new medical technology, as he will explain in his inaugural lecture on 24 March.

A new series of webinars, the Cleveringa Dallaire Critical Conversation Series, begins on 22 September. In this series of online conversations, expert panels from Leiden and abroad will talk about leadership and moral dilemmas in times of conflict and crisis. The series is open to all.

Young transgender people are able to decide together with their parents on a reversible intervention with puberty blockers. These are the results of a study by LUMC Curium and Amsterdam UMC of 74 young people undergoing treatment. Ninety percent of the young people studied proved able to make an informed…

How can a single origami crease pattern be folded into two precisely defined target shapes? Researchers at AMOLF and Leiden University have created an ‘alphabet’ of 140 origami ‘puzzle pieces’ that allows them to do just that, as described today in Nature Physics. This discovery could help in the construction…

Ten years later, a group of veterans still struggle daily with the effects of their deployment to Afghanistan. Sanne van der Wal, a PhD candidate at the Leiden University Medical Center (LUMC), conducted research into the effects of PTSD.

Is it possible to diagnose diseases using molecular switches? The new international consortium LogicLab will address this question. Leiden chemist Sylvestre Bonnet and Leiden pharmacologist Thomas Hankemeier are involved in the project. LogicLab will run for four years and will receive over 3.5 million…

For decades, unmarried girls and women in the Netherlands were forced to give up their newborn children. The impact was profound and persists to this day for the mothers, fathers, relinquished children, and the adoptive families in which they were raised.

The idea that modern humans displaced Neanderthals because they were better protected against toxic smoke components is now under fire. An earlier study that put forward this suggestion has now been refuted by genetic research by scientists from Leiden and Wageningen. This new research was published…

Fishes rely heavily on sound to find their way during migration or dispersal. Many species are affected by noise pollution. Hans Slabbekoorn from the Institute of Biology Leiden received a HORIZON2020 grant of 500,000 euros to study the impact of sound conditions on movement decisions of fishes.

All kinds of reasons have been put forward for why plants apparently fail to make maximum use of the available light. None of these reasons can explain why after two billion years of evolution they are not black, like industrial photovoltaic solar cells. Are we missing something?

We are delighted to announce two new exciting research projects at the Grotius Centre for International Legal Studies! Dr Misha Plagis and Dr Hilde Woker have each received a starter grant for their collaborative research projects. Dr Hilde Woker and Dr Jason Rudall have received funding for their project…

Two researchers at the Faculty of Archaeology have received a Veni award from the Netherlands Organisation for Academic Research (NWO). This award offers promising young researchers the opportunity to further develop their ideas for a period of three years.

On Saturday 28 September we will be running again, for scholars at risk during the Leiden Science Run. Already 56 teams have registered, from Leiden and The Hague students to scientists and companies. There are still spots left for more teams!

Leiden chemical biologists led by Dr Mario van der Stelt have developed a method to facilitate the search for new drugs. This method has allowed them to take an important first step in the development of a drug against obesity.

Cells in our body are constantly performing small tasks, such as repairing wounds. They exert force by changing shape. But how do cells translate their shape into exerting a force in a specific direction? Experimental and theoretical Leiden physicists have now found a clue to answer this question. Cells’…