This thesis investigates innovative and classical strategies in glycoconjugate vaccine development to address the growing threat of multidrug-resistant bacterial infections.

On 7 November 2018, Catherine Harwood defended her thesis 'Navigating Between Principle and Pragmatism: The Roles and Functions of Atrocity-Related United Nations Commissions of Inquiry in the International Legal Order'. The doctoral research was supervised by Prof. dr. L.J. Van den Herik and Prof.…

Százhalombatta-Földvar is a Bronze Age fortified tell settlement on the right bank of the river Danube, 30 km south of Budapest in Hungary. It is one of the best preserved temperate climate tells in Europe and well-known for the extraordinarily rich data it produces. Since 2014 Leiden students are welcomed…

Curved single crystals provide variable, but well-defined surface structures.

This research delves into the unique cultural approach of the Tenggerese people, an Indigenous community in East Java, Indonesia, regarding elderly care. It focuses on their traditional practices of bakti (‘filial piety’) and sayan (‘mutual aid’), deeply ingrained in the community's lifestyle and va…

This book aims to unravel some of the mysteries surrounding this exceptional group of larger-than-life Bronze Age blades.

Can epigenetic changes explain associations between early life stress and health outcomes?

The level of congruence between parties and their voters can vary greatly from one policy issue to another, which raises questions regarding the effectiveness of political representation. We seek to explain variation in party–voter congruence across issues and parties.

In this article, Amandine Lerusse, investigates how the order of performance information affects local politicians’ issue prioritisation decisions.

The lipids in the uppermost layer of the skin, the stratum corneum (SC), play an important role in the skin barrier function. The three main SC lipid classes are ceramides (CER), cholesterol and free fatty acids.

This thesis has shed light on some of the ways in which the local electrolyte composition can differ from the bulk and how these changes in the local reaction environment can determine the activity and/or selectivity of two important electrocatalytic reactions, namely, electrochemical CO2 reduction…

Promotor: P. J. J. Hooykaas Co-promotor: B. S de Pater

This research focuses on the (Quantum) Dynamics (QD) of the reactive scattering of H2 from metal surfaces.

In this conversation-analytic study, the authors analyze conversations between researchers from different disciplines and community members to examine relationship building in real life. This is an open access article under the Creative Commons By license.

The outermost layer of the skin, the stratum corneum (SC), is responsible for the skin barrier function, protecting the body from pathogens, chemicals and other unwanted substances from the external environment. The SC lipid matrix provides the only continuous pathway through the SC and is considered…

Together with Pepijn Tuinier and Thijs Brocades Zaalberg, Sebastiaan Rietjens researched the role of trust in an international intelligence cooperation.

This dissertation reports on the beliefs and perceptions of Chinese and Dutch university teachers regarding the role of research in university teaching and how these beliefs and perceptions can be explained by their cultural, institutional and individual background characteristics

The starting hypothesis of the project is that secrecy is not always inimical to democratic governance as conventional wisdom has it.

The main aim of my Ph.D. thesis is to further explore the value of using early developing zebrafish larvae (up to 5 dpf) as a model to study anxiety-like behaviour and their pharmacological modulation with drugs.

Source: Journal of Investigative Dermatology, Volume 134, pp. S44-S44 (2014) ISBN: 0022-202X

Source: International Journal of Cosmetic Science, Volume 37, Number 1, pp. 148-148 (2015) ISBN: 0142-5463

This project is funded by the Dutch Cancer Society. The project will be part of an ongoing research line aimed at identifying mechanisms of cancer therapy resistance and metastasis. In this project, it will be investigated how the Grainyhead family of transcription factors controls therapy response…

Drawing is one of the most unique human behaviours. Like language, drawing is a mode of communication and a cognitive tool that from an early age allows us to interact with others. Is the early development of drawing skill influenced by the social environment? If so, how?

Promotor: Prof.dr. P. Hooykaas, Co-promotor: Dr. R. Offringa

On the 16th of December, Ruixue Wu successfully defended a doctoral thesis. Leiden University Centre for Linguistics congratulates Ruixue on this achievement!

The skin barrier function is provided by the stratum corneum (SC). The lipids in the SC are composed of three lipid classes: ceramides (CERs), cholesterol (CHOL) and free fatty acids (FFAs) which form two crystalline lamellar structures. In the present study, we investigate the effect of CER chain length…

Promotor: G.R. de Snoo, Co-promotor: H.H. de Iongh, C.J.M. Musters

This five year research project aimed to investigate the role of minor central places in the economy of Roman Central Italy.

From surface science towards industrial practice using high-pressure scanning tunneling microscopy.

Leiden psychologist Wilco van Dijk and communication scientist Jaap Ouwerkerk of VU University Amsterdam published a book about the emotion Schadenfreude. The authors describe what the emotion Schadenfreude really is, when people experience the emotion, and what role it plays in social relations.

Fieldwork

Between 1993 and 2000 the Faculty of Archaeology had a formal cooperation with the Service Régional de l’Archéologie de la Guadeloupe, Direction Regional des Affaires Culturelles (DRAC) and the then director André Delpuech. During that period surveys and excavations were carried out at a number of s…

Rural cult places were of central importance in the non-urbanised areas of ancient Samnium, in central southern Italy. Their development, roles and functions in ancient society, however, remain important research questions. New excavations at one of these sanctuaries, the rural temple of S. Giovanni…

Allosteric modulation has long been recognized as a general and widespread mechanism for the control of protein function. Modulators bind to regulatory sites distinct from the active site on the protein, resulting in conformational changes that may profoundly influence protein function. This concept…

From 20 June to 12 August 2011 a team from the Caribbean Research Group, Faculty of Archaeology, Leiden University and the St. Eustatius Centre for Archaeological Research (SECAR) under the direction of Dr. Grant Gilmore III, Dr. Menno Hoogland, Prof. Corinne Hofman and Dr. Alice Samson carried out…

Digitally Preserving Heritage at Risk

The project aims at contributing to the safeguarding of Palestinian cultural heritage and the enhancement of economic situation through tourism development, by presenting and managing one of the most important archaeological resources, the archaeological site of Tell Balata.

Eyserheide. A Magdalenian Open-Air Site In The Loess Area Of The Netherlands And Its Archaeological Context.

A palaeogeographical reconstruction of Bronze Age West-Frisia (2000-800 BC)

Large-scale excavations at Neumark-Nord 2 (Germany), a very rich Middle Palaeolithic site with excellent preservation of organic (faunal and floral) remains and lithics in fine-grained lake deposits, dating to about 125,000 years ago.

Fieldwork

External PhD candidate Liselore Tissen (Leiden University/Delft University of Technology) has been blogging on the Faces of Science website since March about her daily work as a researcher. ‘Academia is anything but stuffy.’

The Vrijthof excavations (1969-1970)

Excavations on Saba took place between 1987 and 1992, and then in 2001 and 2002.

The aim of the research project is to get insight in the biostratigraphical age and the palaeoecological setting of the Schöningen sites and hominin behavior and subsistence during the late Lower Palaeolithic.

Since 2005 Leiden fieldschools have maintained local collaborations with archaeologists on Martinique carrying out surveys and excavations.

The Middle Paleolithic site of Neumark was first discovered in the 1980’s by German geologist Matthias Thomae.

A scientific assessment of the site selection for the ‘Frontiers of the Roman Empire’ Unesco World Heritage Site.