The genesis of the golden boy-king mythos as exhibited between 1922 and 2022 in relation to Egyptological development with a focus on Dutch reception

Promotor: A.P. IJzerman

International Relations and European Politics is one of the three organisational clusters of the Institute of Political Science.

Drug development is hampered by the limited predictive value of conventional 2D culture systems, which fail to recapitulate the complexity of the disease microenvironment and contribute to high clinical attrition rates.

In a new video lecture (in English) on Universiteit van Nederland, astrophycisist Yamila Miguel tells us about the discovery of the most bizarre planets outside of our solar system.

A full overview of MacBio PhD Theses.

Through metabolism, biochemical processes give rise to the complexity of life. Acquired and inborn errors in metabolism underlie many diseases occurring in man. The challenge for present day medical biochemistry is to find, and integrate, pieces of information at molecular, cell and organismal level…

This long term project in Jordan is at the basis of many specialists’ studies and has several off-shoot projects. The project, with its many approaches, is also a framework for much teaching in Levantine Archaeology at Leiden University, especially concerning fieldwork methods, artefact studies, research…

Promotor: A.P. IJzerman Co-promotor: L.H. Heitman

The Van Loon project sets out to safeguard the archives of Dutch archaeologist Maurits van Loon (Amsterdam, September 22, 1923 - Montpellier, October 12, 2006) and make them accessible for further study.

The current projects of the Molecular Physiology group focus on proteins of the endocannabinoid system, kinases and antibacterial targets. MSc- and BSc-students can contact Jessica van Krimpen-Kraaijenoord to apply for research internships.

Our Talents and Discoveries was a yearly publication by the Faculty of Science of Leiden University, published since 2003. You can read all the editions online. Note that the original publication was in Dutch; the original title translates as 'What we are proud of'. The last booklet came out in 2022,…

Drug development is a time- and resource-consuming process that starts with the discovery and validation of a (protein) target that contributes to pathogenesis or disease progression.

In 1993, Prof.Dr. L.J. Slikkerveer was appointed as Chairman of the Pithecanthropus Centennial Foundation, commemorating the centenary of the discovery of ‘Java Man’ (Pithecanthropus erectus) by Eugène Dubois in 1893 in Trinil, Java, Indonesia with an International Conference at Leiden University on…

Leiden Professor of Translational Rheumatology Hans Ulrich Scherer has one foot in the clinic, where he helps patients, and the other in the lab, where he supervises researchers. He bridges these two worlds in his hunt for autoimmune rheumatic diseases.

The discovery of a new Mersenne prime was discussed on national TV by Hendrik Lenstra and Bas Jansen, who defended his thesis on Mersenne Primes in december, and by Ionica Smeets.

Sensational, is how Leiden Egyptologist Olaf Kaper described the discovery of two new chambers in the tomb of pharaoh Tutankhamun. He hopes that a second set of scans will confirm their presence unequivocally.

Nanodiscs are small, disc-shaped structures designed to mimic biological cell membranes, composed of a lipid bilayer stabilized by scaffold proteins. Membrane proteins play crucial roles in essential processes such as nutrient and waste transport, molecular recognition, and cell signalling, making them…

The Phantom of the Ego is the first comparative study that shows how the modernist account of the unconscious anticipates contemporary discoveries about the importance of mimesis in the formation of subjectivity.

A monthly lecture series about early drug discovery research at Leiden University.

Conference

Lecture

On the 11th of June, Umberto Selva successfully defended his doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Umberto on this great result.

We investigate the molecular basis underlying health and disease and provide answers to existing and emerging health problems. Within this theme, we study diseases ranging from rare genetic disorders to cancer and infectious diseases. We make use of a wide variety of model systems and pursue diverse…

Effective policy-making requires understanding what truly causes a problem. Only then can policymakers develop targeted interventions that achieve desired outcomes.

This project studies travel writing about the Dutch East Indies written between 1800 and the end of the Second World War. By analyzing both Dutch travel texts and Indigenous travel texts in Javanese and Malay, it presents a new, double-voiced perspective on (the historiography of) the Dutch colonial…

Promotor: M. Ubbink, Co-promotor: G. Siegal

This is an Erasmus+ International Credit Mobility project of Leiden University’s Faculty of Science with University of California.

If you would want to set up an alumni network after you graduated in Leiden and returned to your home country, how would you go about it? Seven Leiden alumni in China did not hesitate and decided to just do it! Last year they launched the Leiden Alumni Chapter in China, an initiative which was met with…

Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: Dr. L.H. Heitman

The mission in this division, headed by Laura Heitman, is to design and synthesize novel and better ligands for drug targets. Drug discovery is a lengthy but inspiring adventure. It is often an interplay between academic institutes and pharmaceutical industry, in which scientists at university develop…

Physicist Joost Frenken was interviewed on the radio show 'Langs de Lijn en Omstreken' (Radio 1) about the recent discovery of superconductive graphene. The one-atom-thick material was already known for its strength, flexibility, lightweight and good conductivity.

Annelien Zweemer was awarded three poster prizes for her poster ‘Discovery of an intracellular binding site for small molecule antagonists at the chemokine receptor CCR2’.

At Molecular Physiology we teach the following courses within the Leiden Institute of Chemistry's Chemistry and Life Science and Technology programmes.

The Nobel Prize in Physics 2016 goes to David Thouless, Michael Kosterlitz and Duncan Haldane for theoretical discoveries in the field of topological materials. Haldane spent part of 2008 in Leiden; he is the 14th Lorentz Professor to win a Nobel Prize.

An integrated geo-archaeological research of the hominin site Trinil on Java

Multiple Sclerosis, Parkinson’s and Alzheimer’s disease are the most common neurodegenerative disorders. Unfortunately, no effective treatments are currently available to halt the progression of these neuroinflammatory diseases [1].

Allosteric modulation has long been recognized as a general and widespread mechanism for the control of protein function. Modulators bind to regulatory sites distinct from the active site on the protein, resulting in conformational changes that may profoundly influence protein function. This concept…

Which genes are involved in woodiness and associated traits such as drought tolerance, flowering time, stem elongation, life span, and plant herbivory, and how do these gene regulatory pathways overlap?

In this research group, led by Dr. Joost Beltman, the aim is to employ mathematical and computational dynamical modelling approaches in order to quantitatively and mechanistically understand the dynamical behaviour and regulation of intracellular networks of genes, proteins and metabolites as well as…

Bones hold a wealth of information about a person’s life, revealing details about where they came from, how old they were when they died and what diseases they may have had. Scientists can use this data to piece together aspects of an individual's life, offering valuable insights that can help address…