1,995 search results for “state cell differentiation” in the Public website
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Unpacking the effects of burdensome state actions on citizens' policy perceptions
In this article, Martin Sievert and Jonas Bruder investigated whether and how administrative burdens influences citizens' perceptions of welfare policies and attitudes towards beneficiaries.
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Restraint under conditions of uncertainty: Why the United States tolerates cyberattacks
This new article by Monica Kaminska is part of a special issue for Journal of Cybersecurity, based on a selection of contributions from THe Hague Program for Cyber Norms' 2019 Conference.
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Force sensing and transmission in human induced pluripotent stem-cell-derived pericytes
Pericytes, the mural cells of blood microvessels, are important regulators of vascular morphogenesis and function that have been postulated to mechanically control microvascular diameter through as yet unknown mechanisms.
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promise of bureaucratic reputation approaches for the EU regulatory state
Reputation literature has provided crucial insights about the evolution of the US regulatory state. Daniel Carpenter’s influential account painstakingly demonstrates the relevance of reputation to bureaucratic ‘power’ and to early institutional state-building in the US context. We argue that adopting…
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LUMC to build largest stem cell facility in the Netherlands
The Leiden University Medical Center (LUMC) will start construction this year of the largest non-profit stem cell and gene therapy facility in the Netherlands, and one of the largest facilities in Europe. NECSTGEN – the Netherlands Center for the Clinical Advancement of Stem Cell and Gene Therapies…
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Computational modeling of tumor growth and metastasis and the role of the immune system in tumor destruction
In this project, we aim to obtain a quantitative understanding of the role of the immune system in tumor regression, of the role of tumor cell heterogeneity in cancer growth and of tumor cell migration properties.
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Synthesis of phosphodiester-containing bacterial cell wall components: teichoic acids, capsular polysaccharides and phosphatidyl glycerol analogues
Promotor: G.A. van der Marel, Co-promotor: J.D.C. Codée
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Anti-citrullinated protein antibody B cells in rheumatoid arthritis: from disease-driving suspects to therapeutic targets
PhD defence
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The Relationship between State and Religion in a Changing Dutch Society
In recent decades, the Netherlands’ struggle with multiculturalism has caused an upsurge in public interest in the relationship between state and religion. In this, the Dutch address a subject relevant not just to them, but to all of Europe.
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Literacy: Yao Women, Goddesses of Fertility, and the Chinese Imperial State
Mei-Wen Chen defended her thesis on 29 June 2016
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Freedom of Overflight: A Study of Coastal State Jurisdiction in International Airspace
On 10 June 2021, Merinda Stewart defended her thesis 'Freedom of Overflight: A Study of Coastal State Jurisdiction in International Airspace'. The doctoral research was supervised by Prof. P.M.J. Mendes de Leon en Prof. J.J. Rijpma.
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Arthur RamFaculty of Science
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Growth and development of actinomycetes
We aim to provide new insights relating to the spectacular multi-cellular life cycle of streptomycetes and other actinobacteria.
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Profile 1. State formation in medieval Frisia
Politically speaking, the Frisian coastal area constitutes a special case in late medieval Europe since it was not subject to an overlord as it withstood feudalization in the 13th century. Its many sub regions, which were dominated by elites of small noblemen and freeholders, long time succeeded in…
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Geometry of Vegetation Pattern
One of the effects of climate change is the phenomenon of desertification, a process that occurs in semi-arid and arid areas and causes land degradation as well as vegetation loss. Due to the lack of resources, vegetation self-organizes to sustain itself by forming large-scale spatial patterns.
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Human DNA softer than DNA single-celled life
Single-celled organisms have stiffer DNA than multicellular lifeforms like humans and rice. Theoretical physicists managed to simulate the folding in full genomes for the first time to reach this conclusion. Publication in Biophysical Journal on February 7.
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Vice-rector Erwin Muller wordt staatsraad bij de Raad van State
Vice-rector Organisatieontwikkeling en oud-decaan FGGA Erwin Muller start op 1 april 2026 als staatsraad bij de Afdeling Advisering van de Raad van State.
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’ the Inclusion of Imperial Citizens in the Dutch Post-War Welfare State
Emily Wolff, PhD candidate at Leiden University, wrote a paper about the inclusion of imperial citizens in the Dutch post-war welfare state.
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Foreign intelligence in the digital age. Navigating a state of 'unpeace'.
The Hague Program for Cyber Norms, a research program at the Institute of Security and Global Affairs, published its first policy brief, in which Dennis Broeders, Sergei Boeke and Ilina Georgieva explore the role of intelligence agencies in cyberspace and the (im)possibilities of oversight and regulation…
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Christine MummeryFaculty of Medicine
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How our single-celled relatives package their DNA
A group of single-celled organisms organises its DNA in a similar way to higher organisms such as plants, animals, and fungi. However, the way packaged DNA is read out differs between the two related groups, Bram Henneman discovered. PhD defence on 5 December.
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Katharina Natter, The Politics of Immigration Beyond Liberal States: Morocco and Tunisia in Comparative Perspective
Political Scientist Katharina Natter (Leiden University) advances theory-building on immigration beyond the liberal state and demonstrates how immigration politics can provide valuable insights into the inner workings of political regimes. Connecting scholarship from comparative politics, international…
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Minute molecular movements might lead to more efficient biofuel cells
Leiden researchers have found minute movements in the laccase enzyme. This discovery could lead to the development of much more efficient biofuel cells. Publication in Biophysical Journal.
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Social Forces, States and Hydropolitics of the River Nile: Case Studies of Egypt, Ethiopia, Sudan
This research aims to investigate how different social forces interact with hydropolitics in the Eastern Nile Basin and what are the constraints of engagement.
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Characterization of age-associated immunity in atherosclerosis
Healthy aging is one of the prime goals in today's society and atherosclerosis is among the greatest causes of morbidity in elderly. Cardiovascular disease patients receiving treatment are often of advanced aged and have an aged immune system, which limits translating experimental findings to the pa…
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Josi MarschallFaculty of Social and Behavioural Sciences
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Paul AdriaanseFaculteit der Rechtsgeleerdheid
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Glucocorticoid modulation of the immune response
Glucocorticoids (GCs) are widely prescribed as anti-inflammatory drugs due to their well-established immunosuppressive effects.
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inclusion of (post)colonial migrants in Dutch, French, and British welfare states, 1945-1970
How were (post) colonial migrants included in post-war welfare systems?
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Identification and characterization of developmental genes in streptomyces
Promotor: Prof.dr. G.P. van Wezel
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Early-Modern South India. Dynastic Politics in the Vijayanagara Successor States
This research deals with the royal houses of the Vijayanagara Empire and four of its successor states: Ikkeri, Tanjavur (under both the Nayaka and Bhonsle rulers), Madurai, and Ramnad. This study is thus concerned with dynastic politics and imperial legacies in south India between the 14th and 18th…
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Movements of steroid receptors inside the cell nucleus unraveled
Advanced fluorescence microscopy techniques have revealed how steroid receptors move inside the nucleus. The results were published by a team from Leiden University and the Erasmus Medical Center in Rotterdam, led by IBL-researcher Marcel Schaaf.
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Emilie PrastFaculty of Social and Behavioural Sciences
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under strain - A legal, criminological and economic analysis of welfare states and free movement in the EU
Analysing the ways in which immigration structurally challenges and changes the organization and conceptual boundaries of national welfare states.
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Religion, Class, and the Postwar Development of the Dutch Welfare State
Religion, Class, and the Postwar Development of the Dutch Welfare State. Dennie Oude Nijhuis.
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Political Networks and Social Movements: Bolivian State–Society Relations under Evo Morales, 2006–2016
Book by Soledad Valdivia Rivera
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United States and Chinese foreign assistance and diplomacy: Aid for dominance
United States and Chinese foreign assistance and diplomacy addresses the analytic weaknesses of mainstream analysis of foreign aid, which often focuses on its material dimensions. The book underscores the constitutive relationship between foreign aid as a material resource and the diplomatic discourses…
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Biophysical studies of intracellular and cellular motility
This dissertation combines the use of defined microenvironments, high-resolution fluorescence microscopy, and time-resolved analysis, to study intracellular and cellular motility.
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Omics data integration with genome-scale modelling of dopaminergic neuronal metabolism
Parkinson's disease is the second most common neurodegenerative disease in the world. One of its symptoms is the loss of dopaminergic neurons in the substantia nigra pars compacta.
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Vascular and Regenerative Medicine
Methods of treatment for chronic illnesses are limited. Doctors and researchers at Leiden University Medical Center (LUMC) and Leiden University are working on new therapies as an alternative for organ transplants. The goal is to cure the illnesses by restoring organs to their original function. Stem…
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Serkan AslanFaculty of Science
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Stress-induced modulation of the innate immune system in cardiovascular disease
Promotor: Prof.dr. J. Kuiper
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Bioorthogonal chemistry to unveil antigen processing events
The research described in this thesis focused on the use of bioorthogonal antigens to investigate immunological processes in antigen presenting cells. Bioorthogonal antigens are antigenic proteins produced through recombinant expression in a methionine auxotrophic E. coli strain.
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Research
At the division of Biopharmaceutics, we aim to develop and test new therapeutic approaches to limit or even prevent the development of atherosclerosis in order to reduce the number of acute cardiovascular syndromes such as myocardial infarction or stroke.
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Dame Lab / Chromatin Organization & Dynamics
Throughout all domains of life, from bacteria and archaea to eukaryotes, genomes adopt well-organized three-dimensional structures that can change in space and time to accommodate preferred transcriptional programs for environmental adaptation, the maintenance of cellular identity and differentiation…
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Between life and death: organizational change in central state bureaucracies in cross-national comparison
Identifying and explaining change in the structure of central state bureaucracies and the determinants of survival of individual public organizations are two closely related areas of research in public administration. We aim to bridge the gap between these two main strands of studies of organizational…
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Strategies for braiding and ground state preparation in digital quantum hardware
With the help of quantum mechanics, digital quantum hardware may be able to tackle some of the problems that are too difficult for ordinary computers. But despite these expectations and the ongoing effort of the research community, reliable quantum computers are not yet realized in a lab setting.
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Rethinking digital nationalism in China: state propaganda and public discourse during the first wave of the COVID-19 pandemic
On Wednesday 25 June 2025 Dechun Zhang successfully defended a doctoral thesis and graduated.
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A recipe for desert: analysis of an extended Klausmeier model
Promotores: Arjen Doelman, Jens Rademacher, Max Rietkerk
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Travelling waves on trees and square lattices
In this thesis we study bistable reaction-diffusion equations on lattice domains.