1,333 zoekresultaten voor “have a” in de Publieke website
-
The holographic glass bead game: from superconductivity to time machines
Promotores: Prof.dr. J. Zaanen, Prof.dr. K.E. Schalm
-
Research Seminar Series
For questions and suggestions regarding the series, please contact prof. dr. Olaf van Vliet or dr. Max van Lent
-
Structural characterization of the cell envelope of Actinobacteria under changing environments
Bacteria have the ability to alter their morphology in order to adapt to changing environments.
-
Electrochemical and surface studies of the effect of naphthalene-based additives on tin electrodeposition
Tin electrodeposition applications have rapidly evolved in the past 25 years.
-
Visual analytics for spatially-resolved omics data at single cell resolution: Methods and Applications
The deeper understanding of an organism's pathology is important for developing treatments. Over centuries of systematic research, clinical researchers have demonstrated that the more information they acquire about the cellular properties and their organisation in the tissue, the better they can understand…
-
Synthetic Methodology Towards ADP-Ribosylation Related Molecular Tools
Phosphorylation affects all four major biomolecules – proteins, lipids, carbohydrates and nucleic acids – and plays a pivotal role in the most fundamental cellular functions.
-
Comparative wood anatomy and evolution of Apocynaceae and Sapotaceae
In my research, I used a comparative wood anatomical approach to address wood evolution of the (largely) tropical flowering plant families Apocynaceae and Sapotaceae.
-
Replacing the needle and syringe for vaccine administration
Promotores: Prof.dr. G.F.A Kersten, Prof dr. J.A. Bouwstra
-
Quantitative pharmacological modelling for optimizing treatment of sepsis
Sepsis is a life-threatening condition caused by a dysregulated host response to infection, it is associated with significant morbidity, mortality, and with a high financial burden on global healthcare systems. Bacterial infections are the primary cause of sepsis, but the growing prevalence of antimicrobial…
-
Computational optimisation of optical projection tomography for 3D image analysis
Optical projection tomography (OPT) is a tomographic 3D imaging technique used for specimens in the millimetre scale.
-
Photocleavable activity-based acid glucosylceramidase probes
Lysosomal acid glucosylceramidase (GBA1) is a lysosomal enzyme that degrades glucolipids with its main substrate being glucosylceramide (GlcCer). Defects in the GBA1 gene lead to glycosphingolipidosis Gaucher disease (GD), in which the hydrolysis of GlcCer is impaired and therefore, it accumulates in…
-
Synthetic peptides as tools in chemical immunology
This thesis has described novel synthetic methods to produce a variety of (glyco)peptides and their application in the study of various immunological processes.
-
Synthetic modification of fusogenic coiled-coil peptides
A structural investigation of coiled coil peptides used as membrane fusogens, mimicing naturally occuring coiled-coil fusion proteins. Synthetic modifications have been made to alter lipid attachment, secondary structure and to insert photoactive azobenzene moieties for active control over coiled coil…
-
Optimizing Solvers for Real-World Expensive Black-Box Optimization with Applications in Vehicle Design
Optimally solving real-world expensive Black-Box Optimization (BBO) problems w.r.t. real-world constraints, such as wall-clock time and computational costs, is extremely difficult and tedious.
-
Accountable Artificial Intelligence: Holding Algorithms to Account
Artificial intelligence algorithms govern in subtle, yet fundamental ways, the way we live and are transforming our societies. The promise of efficient, low‐cost or ‘neutral’ solutions harnessing the potential of big data has led public bodies to adopt algorithmic systems in the provision of public…
-
Grensoverschrijdend verkeer t.a.v. moreelgevoelige onderwerpen
Homohuwelijk, draagmoederschap, abortus. Hoe reageert het recht op dergelijke moreelgevoelige onderwerpen bij grensoverschrijdend verkeer binnen de Europese Unie? Op 4 november 2015 promoveert Nelleke Koffeman op dit onderwerp.
-
Operando Spectro-electrochemical investigations of Pt and Pt-alloys as Fuel Cell Catalysts
The overall theme of this thesis is to complement the electrochemical data acquired in fuel cell research with in situ X-ray photoelectron spectroscopy (XPS) and soft X-ray absorption spectroscopy (XAS).
-
Winds in the AGN environment: new perspectives from high-resolution X-ray spectroscopy
Promotor: J.S. Kaastra Co-promotor: E. Constantini
-
Environmental sustainability of NdFeB magnet recycling: foresight study on recycling systems and technologies
The demand for neodymium-iron-boron (NdFeB) magnets is rapidly growing, while the neodymium supply chain is under pressure. Recycling can alleviate these issues. This thesis investigates the potential for deploying novel magnet recycling technologies and their environmental consequences.
-
The role and analysis of molecular systems in electrocatalysis
Molecular complexes can be used as electrocatalysts for oxygen reduction, water oxidation, and/or hydrogen peroxide production.
-
EU JudgeCo Platform
The ultimate aim of this project is to improve cooperation between courts in different Member States.
-
Uniform infinite and Gibbs causal triangulations
Promotor: Richard D. Gill
-
Public and Private Regulation of Financial Markets
How should jurisdictions, both on the national and on the supra-national level, handle the interaction between public and private law where it regards the regulation of financial markets?
-
Knots in plasma
A plasma is an ionized gas with very low electrical resistivity. As such, magnetic field lines are 'frozen in' and move with the fluid. Magnetic field lines that are linked, knotted and tangled, cannot be undone by the fluid motions.
-
Identification of novel targets in prostate cancer progression
Promotor: B. van de Water, Co-promotor: E.H.J. Danen
-
Neutrinos From the Milky Way
Promotor: Prof.dr. M. de Jong
-
Manipulating carbon nanotubes Towards the application as novel field emission sources
Promotores: T.H. Oosterkamp, N. de Jonge
-
Signalling pathways that control development and antibiotic production in streptomyces
Bacteria are highly complex and diverse organisms that have adapted to survive in ecological niches ranging from the most extreme to the most heterogeneous environments.
-
Data-driven donation strategies: understanding and predicting blood donor deferral
The research in this dissertation aims to optimise blood donation processes in the framework of the Dutch national blood bank Sanquin. The primary health risk for blood donors is iron deficiency, which is evaluated based on donors' hemoglobin and ferritin levels.
-
Data science and sports: a winning combination
Athletes always strive for the top. How can data scientists assist them in improving their performance? During the seminar Data Science and Sports, the possibilities and challenges of collaboration between these two worlds were discussed.
-
Rechtsgeleerdheid: eLaw
eLaw onderzoekt de rol van het recht in de informatiemaatschappij: hoe kan het recht bijdragen aan een goede werking van informatie- en communicatietechnologie, en het gebruik ervan door burgers, bedrijven en overheden?
-
Semi-partitioned Scheduling and Task Migration in Dataflow Networks
Promotor: Ed F. Deprettere, Co-promotor: Todor P. Stefanov
-
Topological phases and phase transitions in magnets and ice
The main focus of this thesis is the behaviour of two-dimensional materials, namely (anti)-ferromagnetic materials in the first two chapters, which show topological phases, and energetic square ice in the third and fourth chapter.
-
Science Communication & Society
The research group Science Communication and Society aims to understand how science communication works to improve the interaction between science and society. Central themes are ‘Bridging the gap between experts and the general public’ and ‘Evaluating Science Communication’.
-
Shaping the pharmacokinetic landscape for renally cleared antibiotics in obesity
The prevalence of obesity (BMI >40 kg/m2) has increased rapidly over the recent years, not only in adults, but also in children and adolescents.
-
Onderzoeksgroep Governance of Crises
De onderzoeksgroep Governance of Crises bestudeert fenomenen, dynamieken en actoren die te maken hebben met crisisgovernance. Het Crisis Research Center (CRC) van de Universiteit Leiden maakt deel uit van deze onderzoeksgroep.
-
Lab member Niek Strohmaier part of Kifid’s arbitration committee
As per January 1st, Niek Strohmaier is part of Kifid’s arbitration committee.
-
Read the new ELS Bulletin and the Midterm Report of Empirical Legal Studies
Recently, a new edition of the ELS bulletin was sent out. Furthermore, we are thrilled to share the Midterm Report of the ELS lab @Leiden with you!
-
Design and development of conformational inhibitors and activity-based probes for retaining glycosidases
Glycosidases are essential in fundamental biological processes and are responsible for the degradation of most (oligo)saccharides, glycolipids and glycoproteins.
-
Molecular mystery in space
The space between the stars isn't simply a void; it also contains substances such as methanol and carbon dioxide. So far, chemical theories have been unable to explain how these substances originate under circumstances that should make it impossible. Fedor Goumans has been awarded a Veni subsidy to…
-
mRNA and drug delivery with lipid-based nanoparticles
This thesis focuses on the application of lipid-based nanomedicine in drug delivery, including small molecular antitumor drugs and biomacromolecules including mRNA, and evaluates their biological performance.
-
Imaging of alkyne-functionalized ruthenium complexes for photoactivated chemotherapy
In photoactivated chemotherapy (PACT), a biologically active compound is caged by a light-cleavable protecting group.
-
Connect & FAIRify: FAIRification of a high throughput metabolomics laboratory with FAIR Digital Objects
Webinar, Q&A, discussion
-
Nieuw artikel van Helen Pluut in European Journal of Work and Organizational Psychology
Een nieuw artikel van Dr. Helen Pluut zal verschijnen in European Journal of Work and Organizational Psychology. Het artikel, dat samen met Marion Büttgen en Jan Ullrich van de Universiteit van Hohenheim is geschreven, heeft implicaties voor organisaties die een duaal laddersysteem hanteren. Zulke systemen…
-
Child Sexual Abuse in the Digital Era: Rethinking Legal Frameworks and Transnational Law Enforcement Collaboration
Op 11 juni 2020 verdedigde Sabine Witting haar proefschrift 'Child Sexual Abuse in the Digital Era: Rethinking Legal Frameworks and Transnational Law Enforcement Collaboration'. Het promotieonderzoek is begeleid door promotoren prof.mr. J.J. Sloth-Nielsen en prof.dr.mr. S. van der Hof.
-
Balsaminaceae in Southeast Asia: systematics, evolution, and pollination biology
Balsaminaceae is a diverse plant family characterized by a huge floral morphological diversity.
-
The ecological relevance of chemical diversity in plants
Promotor: P.G.L. Klinkhamer, Co-Promotores: K. Vrieling, P.P.J. Mulder
-
Take part in a join-in course!
As a member of the Research School you can take part in join-in courses. Join-in courses are MA-courses in medieval topics given in set MA-programs of the six participant universities of the Research School. These courses allow you to further specialize in certain topics.
-
From grains to planetesimals: the microphysics of dust coagulation
Promotor: Prof.dr. A.G.G.M. Tielens, Prof.dr. C. Dominik (UvA)
-
Identification and characterization of developmental genes in streptomyces
Promotor: Prof.dr. G.P. van Wezel