Atherosclerosis is a progressive disease resulting in the formation of an arterial plaque. Despite lipid lowering, recurrent cardiovascular events remain a risk. While atherosclerosis is primarily lipid-driven, the immune system plays a critical role in the pathophysiology.

Biological cells, the basic building blocks of all life forms, are surrounded by a lipid membrane. More than half of the membrane is occupied by membrane proteins, which can regulate the cell functionality through specific arrangements.

Almost three years after receiving her honorary doctorate, Dr Graça Machel returned to Leiden University. Over the course of two days she spoke with students, researchers, and other interested persons, about human rights – particularly those of women and children – in a world in which these are continually…

Promotors: Prof.dr. E. Bouwman, Prof.dr. E. Drent

Photocatalysis has emerged as a powerful tool for enabling challenging transformations in organic synthesis. This thesis explores the development of several photocatalytic reactions designed to form carbon-heteroatom bonds from less-functionalized precursors.

Indonesia is experiencing various environmental challenges related to its fast economic growth. Therefore, it is necessary to have measurable and applicable indicators to obtain accurate data and information regarding the costs of adverse environmental impacts arising from economic activities to support…

Promotor: M.T.M. Koper, Co-Promotor: L.B.F. Juurlink

This thesis combines field and laboratory studies to address some of the most pressing questions in the field of microplastic research.

BlaC is the β-lactamase of Mycobacterium tuberculosis. We show that it can recover from inhibition by clavulanic acid and that phosphate helps it do so.

Voor meer informatie kunt u contact opnemen met de director of verantwoordelijk hoogleraar van het Leiden Leadership Centre:

Het Instituut heeft 6 secretariaten voor de verschillende afdelingen.

This thesis describes the implementation and on-sky demonstration of high-resolution integral-field spectroscopy for extreme adaptive optics systems that are used to find and characterize exoplanets.

Bij FAIR-ASSESS zijn onderzoekers betrokken van vijf verschillende Leidse faculteiten, en experts van buiten de universiteit. Het project is opgezet door Andrei Poama en wordt geleid door Josette Daemen.

Op 26 mei 2026 was het Leids Instituut voor Chemisch Onderzoek (LIC) gastheer van een delegatie van promovendi van de Universiteit van Kansas. Zij waren op bezoek bij onze universiteit en bezochten ook het instituut.

Students Practicing Citizen Journalism

Intelligente apparaten zullen ook ethische beslissingen gaan nemen. Mag een zelfrijdende auto voetgangers overrijden om de inzittenden te redden van een frontale botsing? Mag een onderhandelings-app stress in de stem van de tegenpartij detecteren? En wie bepaalt of dit mag, de gebruiker, de maker of…

From surface science towards industrial practice using high-pressure scanning tunneling microscopy.

This thesis aims to demonstrate how the achromatic nature and design flexibility of liquid-crystal optics can be used to improve high-contrast imaging instruments to facilitate detailed exoplanet characterization.

Climate change is a challenge for both current and future generations. New biological resources have to be developed in order to meet the demand for energy as well as the demand for food.

Promotor: Prof.dr. G.J. Kroes

Video games have emerged as one of the most interesting media of the turn of the century. The peculiar characteristic of video games is the biunivocal interaction between the computer and the human player.

Breeding for resistance becomes more and more important because we want to reduce the use of pesticides. A fast and cheap alternative can be to make use of morphological or chemical markers.

Promotor: C.A.M.J.J. van den Hondel, Co-promotor: Sandra de Weert

A difficulty of studies on chemical kinetics are the reaction time scales and detection of their intermediates.

The present thesis focuses on the pharmacological concept of drug-target interaction, which dates back to the beginning of modern pharmacology.

Promotores: Prof.dr. J. A. Bouwstra, Prof.dr. W. Jiskoot

De afdeling Bedrijfswetenschappen houdt zich bezig met vraagstukken op het gebied van ondernemerschap, organisatiepsychologie en insolventie. Op de afdeling werken docenten en onderzoekers uit verschillende disciplines, zoals marketing, economie, finance, strategie en de gedragswetenschappen.

The intradermal administration route is attractive for vaccine delivery, because of the highly populated antigen-presenting cells in the skin. However, the skin’s main physical barrier, the stratum corneum, prevents vaccines from entering the skin.

De masteropleiding International Organisation wordt aangeboden door de Universiteit Leiden in Den Haag. Op deze pagina wordt uitgelegd waarom studenten voor deze opleiding en locatie kiezen.

​Vertelt het verleden ons wie we zijn? Wijst de geschiedenis ons een weg naar de toekomst? Is historisch besef wel nuttig in een samenleving die ingrijpend verandert?

The work presented in this thesis is based on ALMA surveys of protoplanetary disks in three star-forming regions: Lupus, OMC-2, and NGC 2024.

Heterogeneous catalysis is essential to many industrial applications. These catalysts are often comprised of supported nanoparticles, which contain various different surface sites.

This thesis describes a study from both a theoreticaL and an experimental point of view.

The project Multimedia Research and Documentation of African Oral Genres: Connecting Diasporas and Local Audiences (Director: D.Merolla) focuses on multimedia as technology that allows scholars to share documentation and scientific knowledge with the cultural owners of the collected oral genres.

In this thesis, we use low-frequency and high-frequency radio observations to address the following questions regarding quasars: is the radio loud/quiet quasar dichotomy real?

The main goal of the research described in this thesis was the development of new photoactivated chemotherapy (PACT) ruthenium(II) complexes bearing a non-toxic photolabile ligand.

Historische migratiestudies hebben zich lange tijd voornamelijk gericht op de Europese en Atlantische wereld. In dit programmatische langetermijnproject willen we het perspectief verbreden naar de volledige migratie-ervaring van de niet-westerse wereld.

Nieuw handboek geschiedfilosofie van Herman Paul in de reeks 'Wetenschapsfilosofie in context'.

This thesis examines the link between simple molecules and the underlying structure and chemistry within protoplanetary disks - the birthplaces of planets.

De verandering van een gesloten instelling naar een open leefomgeving voor patiënten met een laat stadium van dementie zal de patiënten meer vrijheid geven in hun dagelijks leven. Het effect van deze verandering op de mobiliteit van de patiënten, hun activiteiten en hun interactie met anderen zal worden…

Metal complexes and 2D materials like graphene were combined to produce structures that can function as sensors.

“Temminck’s Order” is the scientific biography of Coenraad Jacob Temminck (1778–1850), a Dutch naturalist and the first director of ’s Rijks Museum van Natuurlijke Historie in Leiden.

CML rapport 192

Cardiovascular disease is the number one cause of death worldwide. The most important risk factor for developing this disease is high cholesterol levels in the blood.

In this thesis, I study the formation of large-scale structure and the physics of particle acceleration at large scales (~Mpc).