Promotor: J. Zaanen, Co-Promotor: V. Juricic

A tidal basin is an inland sea which is almost entirely enclosed by land and connected to the open sea by a tidal inlet. Through the tidal inlets interaction takes place between the tidal basin and the open sea.

All crested and marbled newts (the genus Triturus) suffer from an unusual genetic abnormality, called a balanced lethal system, that kills exactly half of their offspring. How can a trait so disadvantageous have survived millions of years of natural selection?

Promotor: Prof.dr. B. van de Water

Promotores: W. Th. F. den Hollander, M.O. Heydenreich

Multiple stars, that is two or more stars composing a gravitationally bound system, are common in the universe.

Promotor: Prof.dr. J. Kuiper

Cardiovascular disease is the leading cause of death worldwide.

Actinobacteria are well known for the production of bioactive natural products, many of which have applications in the fields of human, animal and plant health. Subject of this thesis are the anthracyclines, glycosylated aromatic polyketides with potent anticancer activity.

Classical statistical methods, such as p-values, are difficult for researchers to apply correctly. They for example do not allow drawing conclusions from a study early, or for extending a study with extra research groups that want to make their data available later.

In the early universe, the dynamics of the Higgs field can give rise to many interesting phenomena.

This dissertation focuses on developing new mathematical and statistical methods to properly represent time-varying covariates and model them within the context of time-to-event analysis.

Promotor: Prof.dr. J.G.E.M. Fraaije, Co-promotor: A. Kros

Promotor: G.P. van Wezel, Co-promotor: D. Claessen

The adenosine receptors are proteins that reside in the extracellular membranes of cells. Activation of adenosine receptors plays a role in many physiological and pathological processes, such as immune responses and cancers.

Promotor: J. Aarts

Bacteriophages, or phages for short, are the most abundant biological entity in nature. They shape bacterial communities and are a major driving force in bacterial evolution.

Promotores: W. Jiskoot, F. Ossendorp

Promotor: S.J. Edixhoven, Co-promotor: R.S. de Jong

Van publieke organisaties wordt in toenemende mate verwacht dat zij maatwerk leveren en de menselijke maat meewegen in besluiten. De toeslagenaffaire, decentralisaties in het sociale domein en problemen bij uitvoeringsorganisaties hebben deze thema’s hoog op de politieke en bestuurlijke agenda gezet.…

Cristina Grasseni’s project

Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.

To get an idea of the science communication products and research that is possible, a few examples of student projects of recent years are shown below.

Promotores: G.A. Persoon, H.H. de Iongh

Promotor: Prof.dr. G.J. Kroes

Promotores: H.S. Overkleeft, G.A. van der Marel, Co-Promotor: R.G. Boot

Over several decades, a variety of computational methods for drug discovery have been proposed and applied in practice. With the accumulation of data and the development of machine learning methods, computational drug design methods have gradually shifted to a new paradigm, i.e. deep learning methods…

Nanoparticles can be used as delivery systems for both small molecules and macromolecules such as proteins, peptides or oligonucleotides. This thesis focuses on the use of liposomes, nanometric vesicles formed by a lipid bilayer enclosing an aqueous core. Liposomes are highly versatile delivery syst…

The research described in this thesis has, using the zebrafish as a model system, shed new light on the intricate relationship between TB and DM2, in particular on the role of leptin, SHP-1 and glucocorticoids.

De Faculteit der Rechtsgeleerdheid verricht hoogwaardig onderzoek naar acht onderzoeksprogramma's.

Online cursus The Importance and Power of Music in our Society

An important part of the SCS specialisation is the internship period. Students will get the opportunity to get to know the field and to apply what they have learned during the courses.

Discovery and development of Central Nervous System (CNS) drugs is hampered by high attrition rates.

Agrobacterium-mediated transformation (AMT) has abundantly been used for scientific research for identifying valuable traits.

Promotor: M.A.G.J. Orrit

Op 23 april verdedigde Rowie Stolk het proefschrift 'Procederende belangenorganisaties in de polder: een interdisciplinair perspectief op de toegang tot de rechter'. Het promotieonderzoek is begeleid door Ymre Schuurmans en Jerfi Uzman.

Promotor: Prof.dr. E. Bouwman, Co-Promotor: S. Bonnet

Promotores: A.P. IJzerman, H.W.T. van Vlijmen

In the thesis the dynamics of strategies is studied from two perspectives.In the first part of the thesis strategies are considered to be opinions present in a community.

Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt

De staf van het Europa Instituut bezit een uitgebreide expertise omtrent het recht van de Europese Unie en de Europese bescherming van de mensenrechten in het algemeen.

Op welke manieren hebben ontwikkeling van digitale technologieën invloed op de samenleving en de regulerings- en juridische kaders binnen de samenleving?

In this dissertation (titled: Exploring the Synergies between Transfer in Reinforcement Learning and Procedural Content Generation) we explore how the two research fields named in the title, namely Transfer in Reinforcement Learning (TRL) and Procedural Content Generation (PCG) can synergize togethe…

A neurocognitive investigation of the development of social performance monitoring in youth growing up in stressful versus non-stressful environments

The thesis is part of a bigger project, the HEPGAME (High Energy Physics Game). The main objective for HEPGAME is the utilization of AI solutions, particularly by using MCTS for simplification of HEP calculations.