Promotor: Prof.dr. T. Schmidt

Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez

This thesis seeks to combine two different research topics; Multi-Objective Optimization and Complex Network Analysis.

Promotores: Prof.dr. G.W. Canters, Prof.dr. T.J. Aartsma

Optimization tasks in practice have multifaceted challenges as they are often black box, subject to multiple equality and inequality constraints and expensive to evaluate.

Promotor: J.P. Abrahams, Co-promotor: T. Grüne

Enzymes are innately sensitive to changes in the amino acid sequence, which largely constrains their evolutionary potential, i.e., evolvability. This evolutionary burden can be alleviated in the presence of stabilizing mutations, which increase the buffering capacity of enzymes to tolerate mutations…

This thesis discusses several questions regarding the double ramification cycle as a Chow class on the moduli space of stable n-pointed genus g curves using tools from so-called logarithmic geometry.

Autophagy is a fundamental degradative process, maintaining cellular homeostasis and functions in host defense against intracellular pathogens, including mycobacteria and Salmonella.

Inflammatory skin diseases such as psoriasis and atopic dermatitis can severely impact both the physical and social aspect of a patient’s life. Aberrant inflammatory responses are thought to be a major causative factor in these disorders, but an abundance of different factors contribute to the development…

Promotor: Prof.dr. E. F. van Dishoeck

The PID-directed shift in PIN polarity has been broadly accepted as one of the essential mechanisms for the regulation of auxin transport polarity.

Promotor: Prof.dr. J.G.E.M. Fraaije, Co-promotor: A. Kros

The studies presented in the work show the potential of the integrative use of biophysical data in defining the structural basis of protein interactions.

For each living organism health is ensured by correct functioning of its cells. Cells therefore have elaborate methods for regulation of their proteins.

Factoren van invloed op arbeidsparticipatie onder mensen met multiple sclerose

Het LIBC is actief betrokken bij training & onderwijs op het gebied van hersenen en cognitie.

This course explains the functions of each international court and tribunal in The Hague. On the basis of cases and interviews with judges and lawyers, this course explores the role of these courts and tribunals and their potential to contribute to global justice.

The aim of this thesis is to present novel techniques for proving cryptographic schemes secure against quantum adversaries. Most results are within the context of an idealized model called the ‘quantum random-oracle model’.

Promotores: H.S. Overkleeft, G.A. van der Marel, Co-Promotor: R.G. Boot

Artificial intelligence algorithms govern in subtle, yet fundamental ways, the way we live and are transforming our societies. The promise of efficient, low‐cost or ‘neutral’ solutions harnessing the potential of big data has led public bodies to adopt algorithmic systems in the provision of public…

De psychologen Fenna Poletiek en Erik de Kwaadsteniet krijgen van vakbond FNV een subsidie om te onderzoeken hoe mensen zich gaan gedragen ten opzichte van werk als ze een basisinkomen krijgen. Hoe gaan ze op zoek naar een antwoord?

Programma's die de symptomen van sociale angst bij kinderen willen verminderen, omvatten doorgaans meerdere onderdelen, zoals blootstelling en mentale herstructurering. Het is onbekend of afzonderlijke onderdelen positieve effecten opleveren bij kinderen of dat een combinatie van onderdelen nodig is…

Human vocal communication and music perception represent advanced cognitive skills, seemingly innate and universal. These faculties encompass a range of perceptual and cognitive abilities. Cross-species research sheds light on the origins of musicality by investigating whether these traits are shared…

Eenzaamheid heeft weinig te maken met alleen zijn. Ook mensen met veel sociale contacten kunnen zich eenzaam voelen. Het gevoel ontstaat wanneer de contacten die je hebt niet overeenkomen met wat je nodig hebt, vertelt Sandra van Dijk bij West Vandaag. In het programma vertelt zij meer over het onderzoek…

Lezing

The studies in this thesis are focused on the physical effects in the flat band materials. The results contain the discovery of strong enhancement of RKKY spin-spin interactions with specific geometric arrangement and dynamical generation of excitonic order parameter with high magnitude.

The thesis explores how interstellar chemistry evolves as a function of time and changing physical architectures during the formation of stars.

Promotores: Prof.dr. J. Schaye, Prof.dr. S.D.M. White (MPA Garching)

Evolution acts via mutations in amino acid sequences. Substitution of essential amino acids leads to a nonfunctional protein. l.

Op 18 september 2019 verdedigde Huw Llewellyn zijn proefschrift 'An Institutional Perspective on the United Nations Criminal Tribunals: Governance, Independence and Impartiality'. Het promotieonderzoek is begeleid door promotoren prof.dr. N.M. Blokker en prof.dr. L.J. van den Herik.

Promotie

Promotor: A. Achúcarro, Co-Promotor: G.A. Palma

Onderzoekers werken al eeuwen aan een atlas van het brein. Maar zelfs in 2017 zijn sommige hersenstructuren nog niet in kaart gebracht, met name in de hersenstam. In dit paper hebben we de test-hertest betrouwbaarheid gemeten van de enige MRI-scan die onderzoekers in staat stelt om de locus ceruleus,…

Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt

Triplet superconductivity refers to a condensate of equal-spin Cooper pairs (pairs of electrons with equal spin).

My PhD research is devoted to studies of the conjectural cluster-algebraic symmetry in the theory of topological string, which is the simplest, however already non-trivial sector in the theory of string.

Nature uses a special class of histone proteins, histone variants, to modulate the properties of chromatin at defined genomic locations.

Onderwijs voor nieuwsgierige en ambitieuze studenten die meer uit hun studie willen halen!

The European Council and the European Commission have a similar role in agenda setting. Both place issues on the EU agenda. However, these institutions have distinct designs. They have different political attributes (the European Council has considerably more political authority) and information-processing…

Promotor: W.Th.F. den Hollander, Co-promotor: F.R. Nardi

This thesis provides explicit expressions for the density functions of absolutely continuous invariant measures for general families of interval maps, that include random maps and infinite measure transformations, not necessarily number systems.

Pericytes, the mural cells of blood microvessels, are important regulators of vascular morphogenesis and function that have been postulated to mechanically control microvascular diameter through as yet unknown mechanisms.

Cardiovascular diseases are still a major concern for the global health.

Internationaal geadopteerde kinderen gebruiken niet meer medicijnen dan hun niet-geadopteerde leeftijdgenoten.