927 zoekresultaten voor “human bacteria pathogens” in de Publieke website
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Discovery and development of inhibitors selective for human constitutive proteasome and immunoproteasome active sites
This thesis describes the design and development of subunit‐selective inhibitors of particular catalytically active subunits of human constitutive proteasomes and immunoproteasomes.
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Impact of land use changes on the human-elephant conflict
Promotor: G.R. de Snoo, W. Kustiawan, Co-promotor: H.H. de Iongh
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ecology of lion (Panthera leo Linnaeus 1975) populations and human-lion conflicts in Pendjari Biosphere Reserve, North Benin
Promotores: G.R. de Snoo, B. Sinsin, Co-Promotor: H.H. de Iongh
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The Interactions of Human Mobility and Farming Systems and Impacts on Biodiversity and Soil Quality in the Western Highlands of Cameroon
Promotors: Prof.dr. G.R. de Snoo, Prof.dr. G.A. Persoon, Prof.dr.ir. H.H. de Iongh
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The developing infant gut microbiota: mathematical predictions of the effects of oligosaccharides
A complex community of microbes develops in the infant gut shortly after birth. We call this community the infant gut microbiota. The microbiota influences the health of the infant, which makes the composition and function of the infant gut microbiota an important topic to study.
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Making up Migrants / Disabled: The pasts, presents, and futures of human classifying
Hoe kunnen we op een interdisciplinaire wijze de classificatie van migranten en mensen met een beperking bestuderen en onderzoekers van deze velden samenbrengen om raakvlakken met elkaar te vinden?
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Afforesting with microbes: disentangling the effect of soil biotic and abiotic characteristics on trees using soil inoculation
In this thesis I examine how soil biotic and abiotic characteristics change and interact throughout the course of afforestation and how they subsequently impact tree performance.
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Proving discriminatory violence at the European Court of Human Rights
Op dinsdag 23 mei 2017 verdedigde Jasmina Mackic haar proefschrift ‘Proving discriminatory violence at the European Court of Human Rights’. De promotor is vice-decaan en hoogleraar internationaal publiekrecht Larissa van den Herik. Hieronder volgt een korte samenvatting van haar proefschrift.
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Catecholamine function, brain state dynamics, and human cognition
Het onderzoek in dit proefschrift kijkt naar de rol van het locus ceuruleus - noradrenalinesysteem in verscheidene aspecten van menselijke cognitie, en de modulatie van de staat van het brein.
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Hard power and the European Convention on Human Rights
Op 18 juni 2019 verdedigde Peter Kempees zijn proefschrift 'Hard power and the European Convention on Human Rights'. Het promotieonderzoek is begeleid door promotoren prof. dr. R.A. Lawson en prof. dr. H. Duffy.
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Adjuvanted nanoparticulate seasonal influenza vaccines
Promotor: W. Jiskoot, Co-promotor: A. Kros
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Yun Shao -
North Sea noise in the Anthropocene: an impact study of human-made impulsive sounds on free-ranging cod
Sound is everywhere in the marine environment and hearing is therefore a very important for stimuli for fish. They use sound for orientation and communication, during migration, aggregation and spawning, but also for detection of prey and predators.
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structure solution and crystallographic studies of the Sso10a2 and human C1 inhibitor protein
Promotor: Prof.dr. J.P. Abrahams, Co-Promotor: N.S. Pannu
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Macrophages inhibit human osteosarcoma cell growth after activation with the bacterial cell wall derivative liposomal muramyl tripeptide in combination
CONCLUSION: This study demonstrates that human macrophages can be induced to exert direct anti-tumor activity against osteosarcoma cells. Our observation that the induction of macrophage anti-tumor activity by L-MTP-PE required IFN-gamma may be of relevance for the optimization of L-MTP-PE therapy in…
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NATO Allies and the Protection of Civilians
In dit artikel bespreken Joachim Koops en Christian Patz de uitgebreide beoordeling van de Duitse gereedheid op het gebied van 'Protection of Civilians' (PoC).
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Quantitative pharmacology of antimicrobials
Antimicrobial drugs constitute a fundamental part of modern medicine. The global rise in antimicrobial resistance poses a major threat to global health.
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Multi-omics studies of the control of growth and antibiotic production of Streptomyces
Actinobacteria are Gram-positive bacteria that have a complex multicellular life cycle and are well known for their ability to produce a wide range of bioactive natural products (NPs).
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Evolutionary adaptability of β-lactamase: a study of inhibitor susceptibility in various model systems
β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…
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Intent on the Paleolithic: Papers in honour of Prof.dr. Wil Roebroeks
This collection of papers was compiled in celebration of the remarkable academic career of Professor Wil Roebroeks, who has established himself as one of Europe’s leading figures in Palaeolithic archaeology over the past three decades and founded the Human origins research group at Leiden University…
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An egg is always an adventure
Anthropogenic change is reshaping ecological systems, raising concerns about increasing transmission of infectious diseases. Among these, mosquito-borne diseases may be particularly sensitive to environmental change, as their transmission depends on vector populations.
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Exploitation of host chemokine signalling by pathogenic mycobacteria
Promotores: A.H. Meijer, H.P. Spaink
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Ethiopian wolf (Canis simensis Rüppell 1835) in a changing landscape: Human carnivore interactions in Afroalpine ecosystems of Ethiopia
Ethiopian wolves are endangered diurnal Afroalpine rodent hunters. I investigated the interaction between wolves, rodents and human land use in Borena Sayint National Park (BSNP), Abune Yosef and Aboi Gara in Ethiopia.
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Towards photo-CIDNP MAS NMR as a generally applicable enhancement method
Promotores: Prof.dr. H.J.M. de Groot, Prof.dr. J. Matysik (Universitaet Leipzig)
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publicatie: Proving Discriminatory Violence at the European Court of Human Rights
Jasmina Mačkić, Universitair Docent Mensenrechten bij het Europa Instituut, heeft haar boek, Proving Discriminatory Violence at the European Court of Human Rights, gepubliceerd. Deze publicatie is gebaseerd op haar proefschrift die Mačkić in mei 2017 heeft verdedigd. Het onderzoek is mogelijk gemaakt…
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Overlapping institutions in the UN human rights system: Mutually strengthening or undermining?
In dit artikel onderzoekt Valentina Carraro de relatie tussen overlappende VN-mensenrechteninstellingen, met name de verdragsorganen en de Universal Periodic Review (UPR).
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of COVID-19 on international organisations, humanitarian action, and human rights
Dit onderzoek toont hoe internationale organisaties reageerden op humanitaire en mensenrechtenuitdagingen tijdens de COVID-19-pandemie.
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Exploring the Versatility of Human β-Glucosidases and Related Glycosylated Metabolites with Novel Chemical Tools
Thesis focused on uncovering the underlying mechanisms of the lysosomal storage disorders Gaucher's disease using chemical tools, biochemical assays and lipidomics.
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Child Marriage as a Choice: Rethinking agency in international human rights
Op 18 maart 2020 verdedigde Hoko Horii haar proefschrift 'Child Marriage as a Choice: Rethinking agency in international human rights'. Het promotieonderzoek is begeleid door promotoren prof.dr. A.W. Bedner en prof.dr. G.A. van Klinken (UvA).
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models to uncover genes driving tumorigenesis and therapy resistance in human breast cancer
To improve cancer treatments, personalized medicine approaches have aimed to identify exactly which mutations are driving tumor development in a given patient and specifically target these mutations using precision therapies.
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culture medium based approach to optimize the stratum corneum barrier of human skin equivalents
uman skin equivalents (HSEs) are in vitro 3D-skin models that mimic many aspects of the native human skin (NHS) and can be a valuable tool.
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Fusing Electrical Stimulation and Wearable Robots with Humans to Restore and Enhance Mobility (Hoofdstuk)
Eduard Fosch-Villaronga, universitair hoofddocent bij eLaw, heeft bijgedragen aan 'Cyber–Physical–Human Systems', een boek waarin de nieuwste ontwikkelingen in interacties tussen cyberfysische systemen en mensen worden onderzocht.
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Intentionality: Balance, Complexity, and Organisation in Artworks by Humans and Apes
Heb je ooit voor een abstract kunstwerk gestaan en gedacht: “Dat had een aap ook kunnen maken!”? Nou, dat heb je mis.
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How can humans and machines collaborate in a meaningful way in a restrictive environment?
In this project, researchers from computer science, law, psychology, and public administration research in practice how artificial intelligence (AI) can be leveraged to make decision-making in the security domain more effective, while also keeping it safe and accountable.
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Interaction with sound for participatory systems and data sonification
This thesis deals with the use of sound in interactions in the context of participatory systems and data sonification. We investigate an interactive environment where participants perceive information of the data through sound elements.
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Humans of Honours: Marleen Fleers
In 'Humans of Honours' staat telkens een medewerker, student of alumnus van de Honours Academy centraal. Deze keer: Marleen Fleers (24), student-assistent internationalisering.
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Autophagy and Lc3-associated phagocytosis in host defense against Salmonella
Control of infectious diseases poses continuous challenges for human health.
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More JAZ in the orchestration of jasmonate-mediated plant defense
Prof.dr. J. Memelink
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Regulation of autophagy-related mechanisms during bacterial infection
Autophagy is a fundamental degradative process, maintaining cellular homeostasis and functions in host defense against intracellular pathogens, including mycobacteria and Salmonella.
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Volatile compounds from Actinobacteria as mediators of microbial interactions
Streptomyces are bacteria abundant in soil that participate in diverse and complex interactions. These bacteria are the main producers of the antibiotics we currently use in the clinic.
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From stress to success; How actinobacteria exploit live without a cell wall
The aim of this thesis was to study phage infection in Streptomyces, focused on cell wall-deficient cells. Bacteriophages (or phages in short) attach to the cell wall of bacteria after which they replicate and lyse the host cell.
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Gratis online cursus Taalwetenschap: Miracles of Human Language
Taal is een beetje als een mobiele telefoon. We gebruiken het de hele tijd, maar eigenlijk weten we helemaal niet zo goed hoe het nou precies werkt. Waar zit taal eigenlijk in ons hoofd? Hebben alle mensen taal? Deze en vele andere vragen worden beantwoord door professor Marc van Oostendorp in de MOOC…
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Tullio Abruzzese -
Humans of Honours: Hine van Os
In 'Humans of Honours' staat telkens een medewerker, student of alumnus van de Honours Academy centraal. Deze keer: honoursstudent Hine van Os (24). Hine loopt coschappen. 'Arts lijkt me een prachtig beroep, maar voorlopig wil ik me meer richten op onderzoek.'
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Towards an effective biodiversity conservation and governance in the Pontocaspian region
Freshwater and brackish water ecosystems are arguably the most vulnerable ecosystems on earth, due to concentrated human developments in and around them. The Pontocaspian (PC) region located at the border of Europe and Asia contains a variety of brackish water ecosystems and unique inhabitants, known…
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Discovering the preference hypervolume: an interactive model for real world computational co-creativity
In this thesis it is posed that the central object of preference discovery is a co-creative process in which the Other can be represented by a machine. It explores efficient methods to enhance introverted intuition using extraverted intuition's communication lines.
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The International Legal Protection of Environmental Refugees. A human rights-based, security and State responsibility approach
Op 7 mei 2020 verdedigde Jolanda van der Vliet proefschrift 'The International Legal Protection of Environmental Refugees. A human rights-based, security and State responsibility approach'. Het promotieonderzoek is begeleid door promotoren prof.dr. N.J. Schrijver en prof.dr.ir. J.J.C. Voorhoeve.
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Biosafety Level 3-laboratorium
Binnen het Leids Universitair Medisch Centrum (LUMC) wordt in verschillende onderzoeksprojecten gebruik gemaakt van pathogene micro-organismen van risicogroep 3. Voor het werken met deze ziekteverwekkers beschikt het LUMC over een onderzoekslaboratorium met hoge inperking om de experimenten voor mens…
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Wild versus domestic prey in the diet of tigers
A recent study on reintroduced tigers in Panna Tiger Reserve in India reveals that risks from tigers increased more because of human behaviour and people's livestock husbandry practices.
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Human Frontier Science Program prijs voor Katharina Riebel
Een internationaal onderzoeksteam metgedragsbioloog Katharina Riebel als hoofdonderzoeker en twee internationale medewerkers ontving een Human Frontier Science Program (HFSP) beurs voor het hun onderzoeksvoorstel ‘Seeing voices’: the role of multimodal cues in vocal learning.