De Minister van Justitie van Sint Maarten heeft een onderzoek laten uitvoeren naar de jeugdcriminaliteit op Sint Maarten.

Alumnus Théo Pavlović heeft de Master Speckmann award ontvangen voor zijn scriptie: PAN RECORDS - A digital journey through the ethnic music niche die begeleid werd door Bart Barendregt. Deze prijs wordt toegekend aan het beste veldwerkverslag voor etnografisch veldwerk. Het bestaat uit een certificaat…

Waarom kies je voor een master in Leiden? We vroegen het een paar van de bezoekers die op 10 oktober naar de Masterdag van W&N kwamen – soms van ver. Ze luisterden naar presentaties, bezochten de infomarkt, bekeken het gebouw. Ze wilden vooral vragen stellen, sfeer proeven en van studenten en docenten…

Het Leids Universitair Medisch Centrum (LUMC) start vanaf 1 september officieel met de bekostigde en reguliere masteropleiding Vitality and Ageing.

Leren samenwerken met mensen van andere disciplines, daar draait het om bij de Master Honours Challenges. In teams pakken studenten een vraagstuk aan voor een organisatie of de samenleving als geheel. Twee deelnemers vertellen wat hun vak bijzonder maakte. ‘Het geeft een bij vlagen ongemakkelijk, maar…

On 8 July, the symposium 'The digital reconstruction of the crucifixion of the Lindau master (ca. 1425)' will take place at the auditorium of Museum Catharijnecovent, from where it will also be broadcasted online.

Op dinsdag 16 april 2019 ontvingen de studievereniging JSV Liberi en de afdeling Jeugdrecht alumni van de master Jeugdrecht tijdens een carrièremiddag en alumni-avond.

Op maandag 1 februari is het tweede semester feestelijk ingeluid op de Sterrewacht. De Afdeling Jeugdrecht en JSV Liberi nodigden twee advocaten uit om te komen spreken over de belangen van de minderjarige in het gezondheids- en vermogensrecht.

Per 1 september 2024 is er geen predicaat cum laude meer voor de master Geneeskunde. Het College van Bestuur besloot onlangs een ontheffing te verlenen voor de faculteit geneeskunde van Universiteit Leiden/LUMC. Het besluit past in de lijn van andere geneeskunde opleidingen in Nederland.

Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.

The book ‘Bestrijdingsmiddelen en Milieu' gives a transparent overview of facts and figures concerning pesticide use in the Netherlands and the impact of pesticides on the environment.

Growth hormone profiles are pulsatile and highly variable between individuals, limiting the implementation of mathemathical models to quantify an individual's secretion.

Global healthcare is on the verge of an antibiotic availability crisis as bacteria have evolved resistance to nearly all known antibacterials. Identifying new antibiotics that operate via novel modes-of-action is therefore of high priority.

Phospholipase A/acyltransferase 3 (PLAAT3) and PLAAT4 are enzymes involved in the synthesis of bioactive lipids. Despite sequential and structural similarities, the two enzymes differ in activity and specificity.

This thesis explores the theoretical and observational properties of distant massive galaxies that harbour active black holes in their centres and shine brightly at radio wavelengths.

Mechanical forces are known to play an important role in bacterial colonies. In this dissertation, we study the self-organization at various stages of growing bacterial colonies, and focus on the mechanical effects of cell growth.

Promotores: H.S. Overkleeft, G.A. van der Marel, Co-promotor: B.I. Florea

Promotor: M.T.M. Koper, Co-promotors: A.I. Yanson, L.B.F. Juurlink

β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…

Organisms often need to adapt more efficiently and devise new strategies for surviving difficult ecological circumstances.

The physical origin of the dozens of stellar-mass binaries, the mergers of which have been detected by the LIGO-Virgo-KAGRA collaboration via gravitational waves, is still unknown.

Promotor: Prof.dr. J. den Hertog

This thesis presents pioneering work on the panchromatic emission of some of the most luminous galaxies in the early Universe: star forming galaxies and active galactic nuclei.

Following the Big Bang, structure in the Universe started collapsing under the force of gravity. This resulted in the formation of the first stars, galaxies and clusters of galaxies.

Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).

The lysosomal β-glucosidase named glucocerebrosidase (GCase) is a retaining β-glucosidase that hydrolyzes the glycosphingolipid glucosylceramide (GlcCer) to ceramide and glucose at acid pH.

The investigations described in this thesis lay out strategies aimed at advancing antibiotic research and development. The examples presented revolve around two main approaches: understanding drug-target interactions and target identification.

Polymyxins are clinically used antibiotics, discovered in mid-20th century. Once abandoned due to excessive nephrotoxicity, they are now used increasingly to address infections caused by multi-drug resistant Gram-negative bacteria.In this thesis, we describe the development and synthesis of analogues…

Advanced sensing techniques require graphene with high quality and well-controlled surface chemistry.

This thesis seeks to combine two different research topics; Multi-Objective Optimization and Complex Network Analysis.

In this dissertation iron-based homogeneous catalysts were synthesized, characterized and investigated for water oxidation activity.

Enzymes are innately sensitive to changes in the amino acid sequence, which largely constrains their evolutionary potential, i.e., evolvability. This evolutionary burden can be alleviated in the presence of stabilizing mutations, which increase the buffering capacity of enzymes to tolerate mutations…

This thesis describes the design and synthesis of fragments of various cell wall carbohydrates of the Streptococcus species, including the branched Group B-specific antigen (GBC) of Group B Streptococcus, glycerol phosphate (GroP) modified group A carbohydrate (GAC), and the O-acetylated type 1 capsular…

As leading cause of death worldwide, cancer is responsible for nearly 10 million deaths in 2020 according to World Health Organization (WHO). Cisplatin and its derivatives are commonly used chemotherapy agents for current cancer treatment in the clinics.

Hydrodesulfurization (HDS) is an ubiquitous part of oil refining that ensures that fuels are cleaned of impurities and environment release of pollutants such as SOx and NOx gasses are minimized.

Promotor: M.T.M. Koper, Co-promotor: J.B.F. Juurlink

One of the key quests in astronomy is to study the growth and evolution of galaxies across cosmic time. Radio observations provide a powerful means of studying the formation of stars and subsequent buildup of distant galaxies, in a way that is unbiased by the presence of dust.

Lezing

An interdisciplinary collection of the best international scholarship on Muslim youth.

Announcement of the publication of Vamping the Stage: Female Voices of Asian Modernities, the first book-length study of women, modernity, and popular music in Asia (University of Hawai'i Press, 2017).

This thesis investigates catalytic reactions at the atomic scale using scanning tunneling microscopy (STM), with a focus on Fischer–Tropsch synthesis, a key industrial process that converts hydrogen and carbon monoxide into liquid fuels.

Beleidsmakers laten zich nog te graag leiden door politieke verhoudingen, particuliere belangen en verkeerde ‘Westerse’ percepties, bevestigt antropoloog Erik Bähre. “Ook bij huisvestingsprojecten in Zuid-Afrika willen ‘wij in het Westen’ niet zien dat we onderdeel van het probleem zijn. Hij onderstreept…

Op 8 september kwamen de studenten van de master European Law bijeen in de Lorentzzaal voor de feestelijke opening van hun programma.

The Utrecht-based VIDI project Lettercraft in Early Medieval Europe, AD 481-751 is working on a new database of Merovingian epistolary communication. We are looking for enthusiastic (R)MA students who would like to join us this Fall as research apprentices for the first phase of data entry and analysis.…

Op 30 oktober jl. bezochten de studenten van de advanced master International Children’s Rights het Internationaal Strafhof te Den Haag.

Op 25 oktober 2017, bezochten de huidige studenten van de advanced master International Children’s Rights van de Universiteit Leiden justitiële jeugdinrichting ‘De Hunnerberg’ in Nijmegen.

Voor studenten die graag een intermediair zijn tussen wetenschappelijke experts, beleidsmakers en politici op het gebied van duurzaamheid, is het masterprogramma Governance of Sustainabiliy wellicht precies wat ze zoeken. De Universiteit Leiden is voornemens deze nieuwe masterstudie in Den Haag te beginnen…

A novel mathematical model describes spatial-temporal drug distribution within one or more brain units, which are cubic representations of a piece of brain tissue with brain capillaries at the edges.

Promotor: Prof.dr. H.S. Overkleeft

Microglia support the central and peripheral nervous system by forming the first line of defense against hazardous events. Microglia are increasingly acknowledged as critical players in neurodegenerative diseases, highlighting them as potential therapeutic targets.