The US travel restrictions are deeply regrettable. Support will be offered to students and staff who are affected.

This article illustrates how the term 'dual use' has become associated with a broader dichotomy between ‘legitimate’ and ‘illegitimate’ purposes.

This month Johan Christensen, assistant professor at the Institute of Public Administration, published his new book: ‘The Power of Economists within the State’. The book explores four countries, Denmark, Ireland, Norway and New Zealand and analyses why these similarly sized and wealthy countries have…

Political scientist Ruud Koole (Institute Political Science, Leiden University) has been appointed to a state commission that will investigate whether the Dutch parliamentary system and the parliamentary democracy need to be reformed.

From 26 to 30 June 2017 a summer course on Europeanisation of administrative law in the Member States of the European Union will be held by the Department of Constitutional and Administrative Law.

On 22 June 2018, Prime Minister Rutte announced that Jaap de Hoop Scheffer, Professor of International Relations and Diplomatic Practices at the Institute of Security and Global Affairs (ISGA), together with former ministers Sybilla Dekker and Winnie Sorgdrager, will become Minister of State.

Drug development critically depends on preclinical models that mimic human physiology, yet traditional two-dimensional cultures and animal models often lack predictive power.

We have developed a microfluidic platform for complex 3D organotypic cell cultures (so-called organ-on-a-chip systems) which are suited for integration in 96 or higher well plate format.

This is a facility where research groups or small companies can apply for space if they need to culture human or animal cells.

On Saturday 9 March 2019, Dr. Eduard Fosch-Villaronga got his first publication for his Marie Skłodowska Curie project on the Legal and Ethical Aspects of Healthcare Robot Technology.

From scanners in lecture halls to systems for working from home: the discussion about new technology is being held on various fronts. That is why the University wants to make more use of its in-house experts. At the Technology and Trust symposium at Leiden University on 2 February, researchers from…

We are happy that the Media Technology staff and students will together again visit the Ars Electronica Festival in Linz (Austria). The five-day study trip offers a shared source of inspiration and a basis for discussion to students and lecturers.

Global science research serves the needs of the Global North, and is driven by the values and interests of a small number of companies, governments and funding bodies, finds a major new international study published today. As such, the authors find, science, technology and innovation research is not…

We are excited to restart the Media Technology alumni talk series, organized by students, for students and alumni. Upcoming edition will bring us two alumni to share their unique journeys after Media Technology: Ella Keijzer and Bastiaan Terhorst.

Associate Professor Gianclaudio Malgieri (eLaw – Center for Law and Digital Technologies) and Professor Margot E. Kaminski (University of Colorado Law School) have published a new article in the very prestigious Yale Journal of Law & Technology, titled Impacted Stakeholder Participation in AI and Data…

As of April 1, 2018, Erik Danen has been appointed as Professor of Cancer drug target discovery at the Leiden Academic Centre for Drug Research (LACDR). His discipline is cell biology of cancer, in which he focuses on the mechanisms underlying metastasis and therapy resistance.

Physics and Engineering Approaches to Biomedicine and Pharmacology

Intrigued by the way cells autonomously regulate their fate, we strive to understand and visualize cellular processes as the basis of Cell Signaling.

Promotor: B. van de Water

Dr. Foks obtained this fellowship for the project “Can promotion of efferocytosis induce regression of atherosclerosis?”, in which she aims to identify novel targets to promote regression of atherosclerosis. This research grant allows her to initiate independent research for the next three years.

Eduard Fosch Villaronga, Assistant Professor at eLaw, co-organised together with Aurelia Tamò-Larrieux, Christoph Lutz, Anton Fedesov, and Anto Čartolovni the GoodBrother International Conference on Privacy-friendly and Trustworthy Technology for Society on 28 June 2022 in Zagreb, Croatia.

Carlotta Rigotti, postdoctoral researcher at eLaw – Center for Law and Digital Technologies, and Professor Clare McGlynn of Durham University have co-authored a new article in the Netherlands Quarterly of Human Rights, titled 'Online and technology-facilitated violence against women: The EDVAW platform's…

Searching for ways to delay the need for a transplant and trying to build kidneys to order.

More and more medicines are becoming available that target a tumour’s specific traits. The use of chemotherapy is continually undergoing improvement.

Chemotherapy that does nothing until you irradiate it with light. Sylvestre Bonnet receives a Vici grant of 1.5 million euros for the development of this treatment. The Leiden chemist wants to build a new molecule to fight tumours that are at the time still difficult to treat.

On Friday 12 March 2021, the (Dutch) website www.codevoorkinderrechten.nl was launched. This code for children’s rights has been created to help those involved in the development and design of digital services to develop these services with the interests of children in mind.

Bacteria caught red-handed, deeply frozen just as they were about to cause Lyme’s disease. Ariane Briegel is wildly enthusiastic about the wonders she observes thanks to three elements: a freezing technique, a camera-equipped microscope, and AI. ‘It’s fascinating. Every single cell is different.’

In the hunt for a vaccine against cervical cancer, fundamental knowledge about the immune system and organic chemistry have been brought together and have already resulted in a vaccine that is now being tested in clinical trials. Scientists are now working hard on an improved variant.

Atherosclerosis (thickening of the artery wall) is the most common cause of heart attacks or strokes, and one of the most common causes of death in the western world. People with this condition have to take medicine all their lives, so a vaccine for atherosclerosis would be a breakthrough.

The Minor Computational Approaches to Disease, Signaling and Drug Targets (CADSDT) is focused on fundamental scientific research required for discovery of new drug targets and development of new drugs.

It’s not something the police force wants to see, but it still occurs: racist and misogynist police conduct. Human rights specialist Dr Linda Louis has studied how technology could help police officers behave correctly and comply with the applicable legal norms.

Bike Labyrinth is international market leader in providing virtual reality exercising for elderly care.

Atherosclerosis is a chronic inflammatory disease affecting millions of people world-wide.

This thesis tackles the difficulty of predicting the liver’s clinical response to novel therapies, a challenge arising from interspecies differences and limitations of existing in vitro models.

The type-IV secretion system (T4SS) is a machinery able to transfer DNA and proteins between bacteria and in certain cases also to eukaryotic cells.

Promotor: Roeland M.H. Merks

List of Support Departments at LION and the Faculty of Science

In the research programme Drug Discovery & Safety, we are interested in the efficacy and safety of new drugs and novel means to decipher these aspects. Hence, we employ advanced imaging and high-throughput screening techniques next to computational approaches such as chem- and bioinformatics.

Promotores: J. Jonkers, K.E. de Visser

Research in the Lars Jeuken group focusses on redox-active proteins and membranes enzymes, aiming to understand bacterial respiration at the molecular level for the development of antimicrobials and semi-artificial photo-synthetic cells.

In previous studies at our laboratory it was demonstrated that drug exposure of HepG2 cells can lead to an altered TNFα-induced NF-κB oscillatory phenotype, concurrent with a synergistically increased sensitivity for TNFα-induced apoptosis.

In human cells, a meter-long DNA is condensed inside a micrometer-sized cell nucleus. Simultaneously, the genetic code must remain accessible for its replication and transcription to functional proteins.

This thesis investigates how cell shape and collective behavior influence the dynamics and structure of biological tissues, which are crucial for understanding processes like embryonic development, tissue regeneration, and metastasis.

Supervisor: P.J.J. Hooykaas

Activity-based protein profiling (ABPP) is a functional proteomics technique for directly monitoring the expression of active enzymes in cell extracts and living cells. The technique relies on irreversible inhibitors equipped with reactive groups (warheads) that covalently attach to the active site…