1,682 search results for “bioactive molecular” in the Public website
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Ad IJzerman wins prestigious Nauta Pharmacochemistry Award
Professor of Pharmacochemistry Ad IJzerman has won the Nauta Award for his years of research into signal processing proteins that are interesting for the development of new medications: G protein coupled receptors. The prize is awarded every two years for services to pharmacochemistry and chemical b…
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Collaborating bacteria sacrifice themselves for the greater good
Like ants, termites and bees, some bacteria work together as a multicellular group. There is a strict division of labour in such colonies, to make the group more resilient to the outside world. Now researchers have found that some parts of the bacterial colony can take ‘for the greater good’ to a whole…
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NWO Open Competition grants for two research projects
Two research projects from Leiden University have been awarded funding within the NWO (Dutch Research Council) Open Competition Domain Science programme. This funding finances innovative, fundamental research of high quality within the domain of Exact and Natural Sciences.
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Unilever Research Prize for master student Lukas Kiefer
Leiden Biology student Lukas Kiefer has won the Unilever Research Prize 2018 for his research into efficient production of a new antibiotic. Kiefer: ‘I want to make biological medicines available to people in need.'
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Different medication dosage for morbidly obese patients
PhD research recently completed by pharmacologist Margreke Brill shows that morbidly obese patients should be given a different dosage of the drugs Cefazolin and Midazolam. This could also apply to other drugs such as anti-cancer drugs as well as antibiotics and Margreke Brill is advocating a change…
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Aggressiveness of cancer cells halted
Zebrafish-human communication shows that cancer cells lacking a signaling protein are less able to develop aggressive metastatic properties. This discovery has been made by molecular cell biologist Claudia Tulotta. PhD defence 14 June.
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How a pathogenic bacterium searches for food
Bacteria whirl around in the mouths of most people, forming dental plaques and sometimes causing nasty gum infections. Treponema denticola might be a dangerous pathogen, but not much is known about this bacterium. It was up to Ariane Briegel and her research group to change that.
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How drugs work better when encapsulated in nanoparticles
Chemist Tobias Bauer discovered ways to improve drugs by encapsulating them. Packages with iron nanoparticles, for example, can stimulate immune cells. Bauer will receive his PhD on 9 June.
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Fighting diseases with good bacteria
Researchers from the Institute of Biology Leiden have discovered how good intestinal bacteria regulate our innate immune system. This surprising discovery could make it possible to treat diseases related to inflammation, such as diabetes and colitis, with a cocktail of good bacteria. Publication in…
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Interdisciplinary research and new friends during LACDR Summer School
From the Republic of Moldova to Italy and from Indonesia to Greece, students from all over the world participated in the Bio-Pharmaceutical Science Summer School 2017. The students got a comprehensive overview of the education and research performed within the LACDR. ‘I am very happy to be here,’ says…
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Observing a changing platinum electrode
The surface of platinum electrodes changes much more during use than was previously thought. In a collaboration between the Leiden Institutes of Chemistry and Physics, chemists Leon Jacobse, Yi-Fan Huang and Marc Koper, and physicist Marcel Rost have been able to show this for the first time. Publication…
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Proactive personality has stronger wake-sleep rhythm
Proactive zebrafish appear to have a much stronger wake-sleep rhythm than reactive fish. In the most reactive fish, rhythmicity appears to be lacking completely. This is shown with research by Leiden biologists, published in December 2018 in the journal BMC Biology.
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How do plants protect themselves against too much sunlight?
That a switching protein plays a role in protecting a plant from too much sunlight was already known, but how exactly was not yet understood. The research group of Anjali Pandit has now discovered that this protein changes shape when there is too much sunlight. The results have been published in Nature…
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Old protein distinguishes bone fragments of Neanderthals
Bone remains that are thousands of years old are often too fragmented to be identified. PhD candidate Frido Welker is the first person to be able to distinguish human bones from one another on the basis of old proteins. PhD defence 18 May.
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A unique defence: Bacteria lose cell wall in the presence of virus
Bacteria temporarily live without their cell wall if dangerous viruses are near. A remarkable feature, as the cell wall is a sturdy barrier against threats. Still, the discovery has a logical explanation ánd might be of a consequence for fighting pathogenic bacteria, according to Véronique Ongenae,…
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Students take a look at the Bio Science Park Neighbours
Many students cycle past the companies of the Bio Science Park every day, but what actually happens behind those doors? And is there a future there for students after their graduation? The Bio Science Park Excursion answers these questions.
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Evolve: Ready to recruit!
The European Union has awarded a COFUND grant to a consortium of researchers from the universities of Groningen and Leiden for a collective PhD programme called ‘Evolve’. The 7.1 M€ programme, which is co-financed by the participating universities, will recruit and train 17 PhD students to conduct world-leading…
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New funding for advanced microscopy using gold nanorods
A consortium of researchers from the Leiden Institute of Physics (LION), the Institute of Biology Leiden (IBL), and the Leiden Institute of Chemistry (LIC) received a FOM program grant to develop a novel way of studying individual proteins inside a cell using gold nanorods.
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Learning together about electron microscopy
Chinese and Leiden scientists came together in Leiden to study the intricacies of modern visual techniques.
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Open Day for international students: ‘I like the Leiden canals’
On Saturday 13 October the historical city Leiden was crowded with prospective students visiting the Open Day. They all came to Leiden to orientate themselves towards studying at Leiden University or to ask questions about the content of the bachelor’s programmes. Among them were a lot of international…
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Madouc Bergers made her own enzyme inhibitors for her bachelor’s thesis
For her bachelor’s thesis, Molecular Science and Technology student Madouc Bergers synthesized her own molecule that can inhibit the breakdown of sugars. Although most students do not even manage to make one building block, Madouc made three. Partly because of this, she has been nominated for the Science…
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26 million for research into the impact of non-genetic factors on health
Who will be affected by certain chronic diseases, and who will not? For 30 percent that depends on heredity factors, whereas no less than seventy percent is explained by external factors. A Dutch research consortium receives 18 million euros from the prestigious Zwaartekrachtsubsidies to study these…
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Exploring the Bio Science Park
On 23 November, more than 70 students visited companies at the Leiden Bio Science. This second edition of the BSP Excursion included a fundamentals track and had a special focus on start-ups.
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International students start a master’s thanks to a LExS
This academic year 49 promising international students will start their master’s degree here thanks to a Leiden University Excellence Scholarship (LExS). The students, all from outside the EU, were welcomed in a special ceremony on 5 September. Who are they?
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Leiden University and LUMC join Netherlands Centre for One Health
Leiden University and Leiden University Medical Center have joined the Netherlands Centre for One Health (NCOH), further strengthening the academic network in which such problems as antimicrobial resistance are studied.
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Youthful DNA in old age
The DNA of young people is regulated to express the right genes at the right time. With the passing of years, the regulation of the DNA gradually gets disrupted, which is an important cause of ageing. A study of over 3,000 people shows that this is not true for everyone: there are people whose DNA appears…
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‘Using real-world data to enhance our healthcare system’
On 16 May 2022, Professor Michel Wouters from the Department of Biomedical Data Sciences at the Leiden University Medical Centre (LUMC), will deliver his inaugural lecture titled ‘Quality of Cancer Care: why the real world matters’. Wouters will use the opportunity to describe how quality registries…
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From robots to populism: students present their Honours work
The second instalment of the Humanities Lab - the three-year honours programme of the Humanities – has reached its conclusion. On 12 May, 11 groups of honours student presented their work in the Arsenaal building.
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Researchers reveal how stem cells make decisions
Embryonic stem cells have the remarkable ability to develop into any type of cell. On their way to become for example a liver or a heart cell, they must repeatedly decide between alternative developmental paths. How they make these decisions is largely unknown. An international team of biophysicists…
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Erasmus+ grant for 13 exchange projects
Thirteen Leiden University exchange projects have been awarded an Erasmus+ International Credit Mobility grant. The total award of around 450,000 euros will enable 103 students and staff to go on an exchange.
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Open Day: 'What's the right degree programme for me?'
Leiden's city centre, bathed in autumn sunshine and teeming with visitors. On 14 October, several thousands of students and their parents came to visit the University's Open Day. We spoke to a number of students at the information fair in the Pieterskerk; each of them had their own questions, doubts…
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Ten thousand types of plant outgrowths bundled
For nine years he worked on the three-volume standard work Plant Galls of Europe. It yielded 2300 pages about 10,000 species of European galls, abnormal outgrowths in plants caused by parasites. Hans Roskam from the Institute of Biology Leiden: ‘The abundance of galls says something about the natural…
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Leiden scientists map cell types in fetal kidney
Kidney failure is a serious issue because kidneys cannot regenerate themselves after injury. A possible solution consists of artificially growing healthy kidney tissue. To achieve that, scientists first need to understand kidney development during the earliest stages, in the fetus. Leiden researchers…
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A ‘lock’ to make genetic modification safer
Genetically modified organisms (GMOs) could be useful allies in the fight against critical environmental problems. Could because the use of GMOs is strictly regulated at the moment. A Leiden student team is now trying to make these GMOs safer with the aid of an ingenious lock.
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LIBC Publieksdag 2025: hoopvolle inzichten in hersenonderzoek
From historical understandings to new treatments: during the Public Day of the Leiden Institute for Brain & Cognition, curious visitors learned how rapidly research into brain disorders is evolving. ‘I found the neurosurgery and the research on organoids on chips particularly fascinating.’
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Huge boost for electron microscopy thanks to NWO grant
Leiden University, together with Utrecht University, the LUMC and 10 other Dutch universities and institutes, has been awarded a grant of more than €30 million in the NWO call Roadmap Large-scale Scientific Infrastructure (GWI).
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SAILS Lunch Time Seminar: Paco Barona Gomez
Lecture
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Het grenzeloze leven: de fascinerende wereld van celwandloze bacteriën
Inaugural lecture
- SAILS Lunch Time Seminar: Applications of Artificial Intelligence in Early Drug Discovery
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LED3 Lecture: Organoids to model human health and disease in vitro
Lecture
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LIC Lecture: Photoswitchable self-assembly
Lecture
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Nathaniel MartinFaculty of Science
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Hermen OverkleeftFaculty of Science
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Artificial Intelligence at the Crossroads of Histopathology: A New Era in Endometrial Cancer Precision Diagnostics and Prognostics
PhD defence
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Microglial lipid metabolism: a delicate balance
PhD defence
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Veni grants for 19 young Leiden researchers
Nineteen researchers who have recently been awarded their PhD are to receive a Veni grant of up to 250,000 euros. Science funding agency NWO has awarded a total of 158 Venis in this round; Leiden University's share of the awards is 12 percent.
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Making everything we know computer-readable
Data and information should be stored in a way that computers can understand, says Barend Mons, professor of Biosemantics at the Leiden University Medical Center and Chair of the High Level Expert Group for the European Open Science Cloud. We speak with him about FAIR data, knowlets and nanopublicat…
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Leiden expands collaboration with Mexico
A delegation from Leiden University is currently visiting Mexico to initiate collaboration with universities and science funding bodies in the country and to extend and expand existing partnerships. Rector Magnificus Carel Stolker is confident enough already to call it a success.
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LED3 & LUCID Drug Discovery Meeting
Conference
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CANCELLED: LED3 Lecture: Covalent Drug Discovery
Lecture