The guardian of our genome, the protein MutS, scans the DNA for spelling errors and makes sure they are corrected. An essential process for our health. Researchers at Leiden University Medical Centre (LUMC) have discovered precisely how this protein works by making MutS visible with cryo-electron microscopy.…

Smart drug carriers, uneven cosmic expansion, and solar energy storage in molecules. These are the topics of three newly awarded NWO-XS grants to researchers at the Faculty of Science.

Scientific Director of the Leiden Academic Centre for Drug Research (LACDR) Hubertus Irth: ‘We test substances and look for new concepts for treating disease.’

Nearly 19,000 runners lined up at the start of Leiden Marathon on Sunday, among them students and staff from the university. For some this was their first race, for others a highlight of their year. This year, in celebration of our 450th anniversary, they ran in a special jubilee t-shirt.

Beads are among the oldest types of human artistic expression. Even so, the small ornaments have a bad status record regarding archaeological investigation. PhD candidate Mette Langbroek, usually at home studying early medieval beads, had the opportunity to work on a publication and exhibition on 5000…

Understanding the behaviour of tiny droplets in our cells could aid the search for new treatments. A team of Leiden researchers has developed a groundbreaking method to study how these droplets transition from liquid to solid. This change plays a role in various diseases, including neurodegenerative…

Cristina Del Real, Assistant Professor in Cyber Crisis at the Institute of Security and Global Affairs, participated in the presentation of the Office of Science and Technology (OficinaC) of the Spanish Congress of Deputies (the Spanish Parliament). She is an expert on cyber security, one of the four…

Fewer CO2 emissions, less airborne viral transmission, and a more sustainable form of food production: seven consortia of researchers and societal partners will put a budget of 32 million euros towards developing technological innovations. Important Leiden research on circular electronics by Prof. Dr.…

With the aid of physics and a minuscule magnet, researchers have discovered a new structure of telomeric DNA. Telomeres are sometimes seen as the key to living longer. They protect genes from damage but get a bit shorter each time a cell divides. If they become too short, the cell dies. The new discovery…

PhD candidate Daniël Gomon has developed statistical methods that could significantly improve research in fields like medicine and demography. ‘Mathematicians don’t like unrealistic assumptions,’ he says. Gomon will defend his PhD thesis on 19 June.

Developing new drugs is a difficult process. With the aid of artificial intelligence, Pharmaceutical scientist Xuhan Liu has developed methods that can help make drug design cheaper and faster. PhD defence on 15 February.

On 15 April, our much-beloved and highly respected former colleague Dr Hans Brussee passed away from cancer. In January 2025, Hans began experiencing neck pain. Initially, it appeared to be a herniated disc, but sadly, the diagnosis was soon revised, and his condition proved untreatable. Hans was 77…

How can Europe lead the way in vaccine development that is fast and for all? To answer this pressing question, Professor of Vaccinology Meta Roestenberg is holding a panel session on 14 July at the EuroScience Open Forum in Leiden.

Leiden researchers, led by Sebastian Pomplun developed a new method to screen hundreds of thousands of molecules for drug discovery, using mass spectrometry instead of DNA tags. ‘We wanted to make drug discovery faster and more accessible.’

On Friday 10 June a workshop on students’ unique skills was organised in the context of the joint Erasmus+ project ASSET-H. In this workshop, teaching staff learned how to showcase the skills that students can learn in their classes. Trainer Catho Jacobs has five tips on helping students to recognise…

PhD defence

An impressive 22 research projects by Leiden researchers have been awarded Veni funding from the Dutch Research Council (NWO).

What does the future of quantum look like? Vedran Dunjko (Assistant professor at LIACS and LION) is co-founder of the applied quantum algorithms (aQa) leiden interdepartmental initiative research that will investigate this. They are part of the Quantum Delta NL consortium that was recently awarded substantial…

Organs and tissues grown in the lab may in the future be able to cure people with organ failures. Micha Drukker, professor of Stem Cells, Developmental Biology and Technology for Innovative Drug Research, is convinced that the use of stem cells will make this possible. He will deliver his inaugural…

Whispp, a Leiden-based speech technology start-up, is developing an app to help people who stutter express themselves more freely. Among those working together with Joris Castermans and his team at Whispp, are researchers and students from the Leiden University Centre for Linguistics (LUCL).

Immunologist Leender Trouw specialises in the complement system, which is part of the immune system. In some diseases drugs help activate or inhibit this system. This is best done ‘in the right place at the right time’ − the title of his inaugural lecture.

‘Let us not forget the power of genuine engagement,’ dean Sarah de Rijcke stressed at the New Year's Reception on 7 January 2025, which was also attended by Rector Magnificus Hester Bijl and addressed the Faculty of Social Sciences.

Patients with skin diseases such as eczema and psoriasis, sometimes spend a lifetime searching for the right medication. To help these patients faster and better, scientists across the country are joining forces. The Next Generation ImmunoDermatology (NGID) project, with LACDR professor Robert Rissmann…

Multidrug-resistant pathogens and worldwide pandemics are increasing, making infectious diseases more prevalent. To develop new treatments, deeper knowledge of the interaction between bacteria and human cells is required. Ariane Briegel recently became a Medical Delta professor and studies such path…

Connecting as the magic word. Seeking new collaborations, presenting ourselves to the outside world with an open attitude and showing what we do. During the opening of the academic year on Tuesday afternoon, Dean Jasper Knoester emphasised that change and connection are necessary for the university…

Professor of Psychiatry Anne Speckens studied medicine in Leiden and did her psychiatry training there too. She opened the Radboudumc Center for Mindfulness in Nijmegen. What does she do there and how does she look back on her time as a student?

Destroying proteins from the Golgi apparatus of the cell in a controlled manner. That is the focus of chemist Marta Artola’s pioneering research. By developing a groundbreaking technology to target specific proteins in the Golgi, Artola aims to unlock new ways for drug development. For this ambitious…

Few researchers see potential in research on glioblastoma, an incurable brain tumour. Alexander Kros brought together colleagues who are up to the challenge. European research funder ERC recently made 10.6 million euros available, a year earlier NWO provided 3 million euros. ‘In six years, we certainly…

How do you behave towards patients with life-threatening conditions who do not want to know all the details of the state of their health? This question brought psychologist Liesbeth van Vliet and anthropologist Annemarie Samuels together. It’s an unusual partnership, but their interdisciplinary approach…

Seven Leiden professors have been elected as members of the Royal Netherlands Academy of Arts and Sciences (KNAW). In total 23 new members will be inaugurated on Monday 13 September.

Thanks to a clever research method, progress is being made in the quest for better tuberculosis medications. Within an American consortium that received a 30 million dollars grant, Leiden researcher Rob van Wijk plays a significant role. ‘The next breakthrough in tuberculosis research will come much…

Charlotte Poot (31) is co-founder and chair of Hospital Hero, an app that prepares children for a hospital visit. She studied and obtained her PhD at the LUMC.

Skåne University Hospital, Lund University and Leiden University Medical Center will work together to expand their research, teaching and development relating to Advanced Therapy Medicinal Products. That is the essence of a Memorandum of Understanding signed at SciLifeLab near Stockholm on Wednesday…

Prof. Marcel Reinders is a data science specialist at Delft University of technology. Using smart algorithms, he searches for links in complex data. For example, he studies patterns in DNA that lead to aberrant cell behaviour. This knowledge will help detect serious diseases such as Alzheimer's and…

Rewarding good behaviour, instead of punishing it – a proven pedagogical method. Would it also work in tackling tax avoidance? This question sparked the interest of PhD candidate Josephine van der Have. Her research investigates the potential of a trademark for fair taxation.

What started as an idea during a social gathering led to an unexpected breakthrough in research on resistant bacteria. Biologists and chemists from Leiden developed a new substance that proves to be effective against bacteria resistant to antibiotics. They published their discovery in Nature Chemist…

Defending your PhD research in front of nearly 300 elementary school students: that was the challenge faced by PhD candidates Jo-Anne Verschoor and Marinka de Willigen during the VUURVLIEGEN competition organised by the Centrum JongerenCommunicatie Chemie (C3). After an exciting competition, the children…

How safe are the nanoparticles in transparent sunscreen, anti-odour socks and bacteria-resistant plasters? Although microbes are present on all organisms, the tools that estimate the safety of nanomaterials still hardly take them into account. Bregje Brinkmann explored the role of these microbes during…

Bacteria carry countless hidden treasures in their DNA: fragments that could hold the key to new medicines. But how do you pick out the most promising ones from millions of options? ‘Look at the switches that turn genes on and off,’ says molecular biologist Gilles van Wezel.

Sometimes an idea seems so logical and elegant at first glance, that you later wonder why no one thought of it before. Two researchers from LACDR have teamed up to develop a completely synthetic alternative to antibodies—one that mimics their size, shape and function, but which is cheaper, more stable,…

Erik Danen is the new Dean of the Graduate School from 1 January. He is a professor at the Leiden Academic Centre for Drug Research and conducts research into cancer drugs. Danen is really looking forward to it: ‘PhD candidates are a special group: that's what I like to dedicate myself to.’

If an echo (or ultrasound) shows that a foetus has a heart or other defect, parents face difficult decisions. Then an idea of their child’s shorter and longer-term future is literally a matter of life and death. Haak will argue in her inaugural lecture that the cohort studies of rare diseases that are…

The Dutch research funding landscape is changing. What developments can senior grant adviser Walter van Raaij see? And what are his tips for a successful grant application?

The doctor suggests opting for a treatment that is better for the environment. How do patients react to this? Doctors and psychologists together discovered that this has little impact on patient confidence in the doctor.

Conference, Seminar

PhD defence

PhD defence

Alumni event, Career

Professor Bussemaker and Professor Koenders draw lessons from the handling of the current corona crisis. In a blended guest lecture with some 60 students in Wijnhaven and some 250 online participants, they entered into a discussion led by Willemijn Aerdts. The guest lecture took place on May 25.