2,911 search results for “states cell biology” in the Public website
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The role of the interleukin 12 family in atherosclerosis
Promotor: Prof.dr. J. Kuiper, Co-promotor: Saskia C.A. de Jager
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Leiden biology student finalist UN youth delegate
Roel Wouters (24), a biology student at Leiden University, is a finalist in the election for UN youth delegate for Biodiversity and Food. The digital polls open for a week on Friday 22 October. Under-30s can vote for Roel at www.stemroel.nl.
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Historicizing Security. Enemies of the State, 1813 until present
The research project ‘The History of National Security, 1945-present', is funded by the Netherlands Organisation for Scientific Research (NWO), the Campus The Hague/Leiden University and the Netherlands Institute for Military History (NIMH). The project will run until the summer of 2013, when we hope…
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Solid State NMR and modelling of photoinduced energy and electron transfer
Huub de Groot is professor in Biophysical Organic Chemistry. With his team he works in the field of photosynthesis and artificial photosynthesis. The molecular basis for photosynthesis is formed by protein complexes and organelles that contain chlorophyll molecules. The antenna systems herein capture…
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Dynamics and regulation of the oxidative stress response upon chemical exposure
The focus of the described research in this thesis is on the oxidative stress response (Nrf2 pathway). The aim of the research presented in this thesis is to obtain more information concerning microRNAs which are involved in the Nrf2 pathway, to determine and evaluate the application of microRNAs for…
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White blood cells in transparent embryos
Leiden molecular cell biologists in the research group of Annemarie Meijer have discovered novel early macrophage-specific genes in zebrafish, including a signal transducer pivotal for the migration of macrophages in the innate immune response to bacterial infection. Their findings were published on…
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The state of STI and research funding flows in Africa
This project aims at providing a broad perspective of the state of Science Technology and Innovation (STI) in Africa with a focus on global funding flows, in order to inform research funders in the continent, in particular those participating in the Science Granting Councils Initiative (SGCI). The project…
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State-resolved studies of CO2 gas-surface reactions
The adsorption of D2 and CO2 on catalyst surfaces is studied using a molecular beam in ultra-high vacuum.
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Small molecule prevents tumour cells from spreading
Leiden chemists, together with colleagues at the University of York (UK) and Technion (Israel) have discovered a small, sugar-like molecule that maintains the integrity of tissue around a tumour during cancer. This molecule prevents tumour cells from spreading from the primary cancer site to colonise…
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Two-photon microscope captures plant cells
Leiden physicists are helping Wageningen plant researchers to study unpredictable plant embryos. For this, they are using a novel two-photon fluorescence microscope, aided by a 30 thousand euro ZonMW grant.
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New insight into immune cell behaviour offers opportunities for cancer treatment
An international group of scientists has discovered that certain cells of our immune system – the so-called T cells – communicate with each other and work together as a team. To fight an infection they stimulate each other’s growth, but at the same time, they inhibit each other when there is a surplus…
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Saloni SaxenaFaculty of Science
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Major European subsidy for Leiden evolutionary biology
Paul Brakefield, Professor of Evolutionary Biology at the Institute of Biology in Leiden (IBL) has been awarded an ERC Advanced Grant for his research. He will receive 2.5 million euro to develop his research programme over a period of five years.
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Chemical Tools to Illuminate N-acylphosphatidylethanolamine Biosynthesis
This thesis describes the development and optimization of the first molecular tools to study the enzyme PLA2G4E.
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Delegation of Holland Rijnland visits the Institute of Biology
On Thursday the 24th of November, Tseard Hoekstra and Jeroen Ververs (members of the delegation Holland Rijnland), Geert de Snoo (Dean Faculty of Science), Martina Vijver (CML), Herman Spaink (Scientific Director IBL) and Klaas Vrieling (IBL) explored possibilities for collaborations between companies…
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Chemical tools to study lipid signaling
Synthesis and application of chemical biology tools to study immunomodulatory signaling lipids.
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Careful restart Cell Observatory and labs
With the necessary measures, researchers restart their work in various laboratories. The Leiden Cell Observatory is one of the places where scientists resume their lab work.
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Business Interests and the Development of the Modern Welfare State
This edited volume provides a synthesis on the question of business attitudes towards and its influence over the development of the modern welfare state. It gathers leading scholars in the field to offer both in-depth historical country case studies and comparative chapters that discuss contemporary…
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Reijer PasschierFaculty of Law
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Josi MarschallSocial & Behavioural Sciences
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Cancer cells play hide-and-seek with immune system
When the immune system attacks cancer, the tumour modifies itself to escape the immune reaction. Researchers at LUMC published on this subject in Nature on 28 June.
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‘There’s still much to discover in developmental biology’
It is the dream of Professor Susana Chuva de Sousa Lopes to grow fertile egg cells in the lab. But she says there is a long way to go in her discipline until that is possible. This is the message of her inaugural lecture on 29 June 2020, the first digital inaugural lecture at Leiden University.
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Chengyi LiuFaculty of Science
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Louie KrolFaculty of Science
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Institute of Biology Leiden assessed as excellent
An external visitation committee gave the Institute of Biology Leiden (IBL) an outstanding assessment. In terms of research quality and relevance to society, the IBL gets the highest score: excellent. The increase with five new female professors also receives praise from the committee.
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State-building, Lawmaking, and Criminal Justice in Afghanistan
On 22 June, Najib Amin defended the thesis 'State-building, lawmaking, and criminal justice in Afghanistan: a case study of the prison system’s legal mandate, and the rehabilitation programmes in Pul-e-charkhi prison'. The doctoral research was supervised by Jan Michiel Otto and Pauline Schuyt.
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Vidi Grant for Stefan Semrau: how does bioelectricity shape embryonic development?
Leiden biophysicist Stefan Semrau was granted an NWO Vidi earlier this month. He will use the grant to study the role of electricity in embryonic development and tissue regeneration.
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Quantum particles and bacteria without cell walls: KLEIN grant for Beenakker and Claessen
Are Weyl particles the ideal conductors? Do cells without a cell wall play a role in chronic Tuberculosis infections? Carlo Beenakker and Dennis Claessen want to answer these questions. They both received a KLEIN grant from the NWO. With these grants, NWO wants to stimulate innovative, fundamental r…
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Development of a Secret State. The Intelligence & Security Services and their contribution to the National Security State, 1945-1989
Subproject of
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Serkan AslanFaculty of Science
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Stress-induced protein dynamic and growth arrest in C. elegans during development
During post-embryonic development into adults, animals face an environment that fluctuates constantly. For example, in nutrient availability, temperature, and osmolarity (e.g., salt concentration).
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The Development of the Pivot State Concept Based on Mackinder’s Heartland Theory
The research addresses the question of “what is the impact of geopolitical changes to the pivot states in the Middle East? With special focus on Turkey, Iran and Saudi Arabia.”
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Modulation of the immune system for treatment of atherosclerosis
Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.
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The United States and China in the Era of Global Transformations: Geographies of Rivalry
This book offers a comprehensive analysis of China's global resurgence and its effects on U.S. dominance.
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Young, sleeping memory cells are crucial in fighting a reinfection
Researchers from the Netherlands Cancer Institute, the Leiden University Medical Center (LUMC) and Oncode have created a tracking system that can reveal how often cells have divided. This allowed them to find a yet undiscovered population of immune cells: young memory cells that behave like stem cells.…
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Specialised immune cells have potential for new cancer immunotherapies
Researchers from Leiden University Medical Center (LUMC) and Netherlands Cancer Institute (NKI) have discovered how specialised immune cells can detect and remove cancers that are ‘invisible’ to the conventional defence mechanisms of the immune system. Their work has been published in Nature. The findings…
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How killer -T-cells migrate towards virus-infected cells
Joost Beltman (LACDR, Leiden University) has provided novel insights in the way T cells migrate towards virus-infected cells. This was accomplished by a combination of experimental research in the group of Ton Schumacher (Dutch Cancer Institute, NKI) and computer simulations in collaboration with Rob…
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(Non)recognition of legal identity in aspirant states: evidence from Abkhazia, South Ossetia and Transnistria
Ramesh Ganohariti will examine legal identity in three post-Soviet aspirant states and outline four common scenarios in this article.
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Aid Imperium: United States Foreign Policy and Human Rights in Post-Cold War Southeast Asia
Does foreign aid promote human rights?
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Edi GittenbergerFaculty of Science
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New cell therapy facility at Leiden Bio Science Park
American pharmaceutical company Bristol Myers Squibb will be building a new (CAR-T) cell therapy facility in the Oegstgeest part of the Leiden Bio Science Park. The company will manufacture and develop CAR T-cell therapy for patients with blood cancer (leukaemia), for example.
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How cells talk by pulling on a fibre network
Mechanics play a larger role in blood vessel formation, and other developmental biology, than previously thought. Cells appear to respond to mechanical signals, such as pressure. Through the extracellular matrix, a network of fibrous proteins, cells can supposedly exchange those mechanical signals over…
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Quantitative Super-Resolution Microscopy
Promotor: T. Schmidt
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Bregje BrinkmannFaculty of Science
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How oxygen deprivation causes cancer cells to spread
In breast cancer, metastasis rather than the primary tumour is the cause of death. A lack of oxygen in the tumour cells promotes this metastasis, accompanied by a reprogramming of the cell's metabolism. PhD candidate Qiuyu Liu investigated these alterations to get more knowledge about the actionable…
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New Scientific Director for the Institute of Biology Leiden
Gilles van Wezel has been appointed the new Scientific Director of the Institute of Biology Leiden starting September 1st, 2018. Van Wezel succeeds Herman Spaink, who has been the Scientific Director since September 2014.
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Quantum dots in microcavities: From single spins to engineered quantum states of light
A single self-assembled semiconductor quantum dot in a high-finesse optical microcavity - the subject of this thesis - is an interesting quantum-mechanical system for future quantum applications. For instance, this system allows trapping of an extra electron and thus can serve as a spin quantum memory,…
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Principles of Evidence in Investor-State Arbitration, Burden, Standards, Presumptions & Inferences
On 28 February 2019, Kabir Duggal defended his thesis 'Principles of Evidence in Investor-State Arbitration, Burden, Standards, Presumptions & Inferences'. The doctoral research was supervised by Prof. dr. E. De Brabandere.
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Into the ether or the state? Legibility theory and the cryptocurrency markets
In this article, the authors explore why there is substantial cross-national variation in the level of regulatory clarity surrounding cryptocurrencies
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Sensing drug responses of single cells using optical tweezers
Light can be used to apply forces on single cells. Focused lasers have been used by physicists to tweeze particles and to manipulate them. These so called “optical tweezers” can be used as mechanical phenotyping tools for characterising the mechanics of materials and living objects.