Leiden biophysicists have found a new possible way to attack cancer cells. They have located ‘sinkholes’ on the cells where receptor proteins disappear from the surface. If a drug could push these proteins towards those areas, it would kill the cancer cell.

This book offers a comprehensive analysis of China's global resurgence and its effects on U.S. dominance.

Does foreign aid promote human rights?

Ramesh Ganohariti will examine legal identity in three post-Soviet aspirant states and outline four common scenarios in this article.

A bacterium hiding from the immune system and picking up bits of DNA from its environment. The result: gaining new traits, such as better protection against antibiotics. Fortunately, we have not found such a damning scenario yet. However, PhD student Renée Kapteijn did find the first clues, which…

This research project is funded by a subsidy from Instituut Gak.

The first index to measure product safety, sustainability, and circularity, operationalising the EU’s (SSbD) framework.

The Altai region has yielded a cluster of Middle and Upper Paleolithic stratified sites that have been recently excavated using a multidisciplinary approach.

The RISIS project aims at creating a distributed research infrastructure to support and advance science and innovation studies. This will give the field a strong scientific push forward, and at the same time, provide a radically improved evidence base for research and innovation policies, for research…

Geneticist Hans Clevers will give the first Niko Tinbergen lecture new style on 10 December, which is all about stem cells. The young Leiden professors Ariane Briegel and Susana Chuva de Sousa Lopes talk about bacterial noses and the cultivation of egg cells in the lab in short introductory lectures…

Theoretical physicist Luca Giomi receives a 2 million euro ERC Consolidator Grant for research into flowing cells in a strange hexatic phase, which is half fluid, half solid.

Ilze Bot wants to reduce the prevalence of cardiovascular diseases. Her research focuses on mast cells, which protect us from infections but can also make us ill.

With the rise of information and communication technologies, large amounts of data are being generated and stored in databases. In order to get a better grip on these large amounts of data, serious efforts are being made to discover patterns and relations in the data with the help of new techniques.…

A single self-assembled semiconductor quantum dot in a high-finesse optical microcavity - the subject of this thesis - is an interesting quantum-mechanical system for future quantum applications. For instance, this system allows trapping of an extra electron and thus can serve as a spin quantum memory,…

In this article, the authors explore why there is substantial cross-national variation in the level of regulatory clarity surrounding cryptocurrencies

On 28 February 2019, Kabir Duggal defended his thesis 'Principles of Evidence in Investor-State Arbitration, Burden, Standards, Presumptions & Inferences'. The doctoral research was supervised by Prof. dr. E. De Brabandere.

The Leiden University Medical Center (LUMC) will start construction this year of the largest non-profit stem cell and gene therapy facility in the Netherlands, and one of the largest facilities in Europe. NECSTGEN – the Netherlands Center for the Clinical Advancement of Stem Cell and Gene Therapies…

Pericytes, the mural cells of blood microvessels, are important regulators of vascular morphogenesis and function that have been postulated to mechanically control microvascular diameter through as yet unknown mechanisms.

The authors explore the decision-making processes and debates surrounding EU member states' troop contributions to CSDP military deployments.

In this book, Lydie Cabane examines the history of disaster management in South Africa.

Luca Giomi has the first results of his ERC consolidator grant. He discovered that epithelial cells move collectively but in different ways, depending on the scale you look at. It is hexatic at small scales, and becomes nematic at larger scales: it is a multiscale order. This collective movement of…

Organ-on-chip technology is used in drug research and customized treatments for patients. Research Institutes and industry join forces within the Institute for human Organ and Disease Model Technologies (hDMT) that was officially launched on May 18. Combining facilities, people and expertise will allow…

The Netherlands Council of State ruled at the end of March that WhatsApp and text messages on the work and private cell phones of civil servants are considered to be official records. This decision puts the government in a difficult position. How are you going to store millions of texts and WhatsApp…

Promotor: G.A. van der Marel, Co-promotor: J.D.C. Codée

We aim to provide new insights relating to the spectacular multi-cellular life cycle of streptomycetes and other actinobacteria.

In this article, Martin Sievert and Jonas Bruder investigated whether and how administrative burdens influences citizens' perceptions of welfare policies and attitudes towards beneficiaries.

This new article by Monica Kaminska is part of a special issue for Journal of Cybersecurity, based on a selection of contributions from THe Hague Program for Cyber Norms' 2019 Conference.

The process of unification and the character of the union are the central topics of Magnanimous Dukes and Rising States. Robert Stein mirrors continuity and modernisation in Burgundian times with the bankruptcy of the former dynasties and the decline of feudal government. The powerful towns played an…

Reputation literature has provided crucial insights about the evolution of the US regulatory state. Daniel Carpenter’s influential account painstakingly demonstrates the relevance of reputation to bureaucratic ‘power’ and to early institutional state-building in the US context. We argue that adopting…

Single-celled organisms have stiffer DNA than multicellular lifeforms like humans and rice. Theoretical physicists managed to simulate the folding in full genomes for the first time to reach this conclusion. Publication in Biophysical Journal on February 7.

In recent decades, the Netherlands’ struggle with multiculturalism has caused an upsurge in public interest in the relationship between state and religion. In this, the Dutch address a subject relevant not just to them, but to all of Europe.

Mei-Wen Chen defended her thesis on 29 June 2016

On 10 June 2021, Merinda Stewart defended her thesis 'Freedom of Overflight: A Study of Coastal State Jurisdiction in International Airspace'. The doctoral research was supervised by Prof. P.M.J. Mendes de Leon en Prof. J.J. Rijpma.

A group of single-celled organisms organises its DNA in a similar way to higher organisms such as plants, animals, and fungi. However, the way packaged DNA is read out differs between the two related groups, Bram Henneman discovered. PhD defence on 5 December.

Politically speaking, the Frisian coastal area constitutes a special case in late medieval Europe since it was not subject to an overlord as it withstood feudalization in the 13th century. Its many sub regions, which were dominated by elites of small noblemen and freeholders, long time succeeded in…

Leiden researchers have found minute movements in the laccase enzyme. This discovery could lead to the development of much more efficient biofuel cells. Publication in Biophysical Journal.

Cell-based medicinal products (CBMPs) belong to an innovative and heterogeneous group of medicines called advanced therapy medicinal products (ATMPs). The limited analytical toolbox for CBMP characterization and release testing is one of the reasons why CBMP development is so challenging.

The Hague Program for Cyber Norms, a research program at the Institute of Security and Global Affairs, published its first policy brief, in which Dennis Broeders, Sergei Boeke and Ilina Georgieva explore the role of intelligence agencies in cyberspace and the (im)possibilities of oversight and regulation…

Emily Wolff, PhD candidate at Leiden University, wrote a paper about the inclusion of imperial citizens in the Dutch post-war welfare state.

Healthy aging is one of the prime goals in today's society and atherosclerosis is among the greatest causes of morbidity in elderly. Cardiovascular disease patients receiving treatment are often of advanced aged and have an aged immune system, which limits translating experimental findings to the pa…

The article offers a comparative systematic literature review of the principles, norms, and strategies associated with Security by Design and Privacy by Design

Political Scientist Katharina Natter (Leiden University) advances theory-building on immigration beyond the liberal state and demonstrates how immigration politics can provide valuable insights into the inner workings of political regimes. Connecting scholarship from comparative politics, international…

Promotor: Prof.dr. G.P. van Wezel

The European Commission has officially established Euro-BioImaging – which provides life scientists with open access to a broad range of technologies and resources in biological and biomedical imaging – as a European Research Infrastructure Consortium (ERIC). The Cell Observatory in Leiden is part of…

Advanced fluorescence microscopy techniques have revealed how steroid receptors move inside the nucleus. The results were published by a team from Leiden University and the Erasmus Medical Center in Rotterdam, led by IBL-researcher Marcel Schaaf.

This research aims to investigate how different social forces interact with hydropolitics in the Eastern Nile Basin and what are the constraints of engagement.

Understanding the water use of power production is an important step to both a sustainable energy transition and an improved understanding of water conservation measures. However, there are large differences across the literature that currently present barriers to decision making.

We are aiming to develop novel technologies to allow better sample preparation or coupling of analytical methods to (i) analyse ultra small samples, (ii) to analyse more metabolites in a quantitative manner and/or (iii) increase the sample throughput.