Promotor: R. Gill, Co-promotor: P. Massart

Heterogeneous catalysis is one of the fundamental processes of modern life, being common in industrial refinery and hydrogen vehicles, all the way to the living cell. The dissociation of H2 on Cu(111) is an important benchmark system for studying heterogeneous catalysis, with a large and varied amount…

A common method to solve expensive function evaluation problem is using Bayesian Global Optimization, instead of Evolutionary Algorithms.

Promotor: Prof.dr. J.P. Abrahams, Prof.dr. M. van Heel

Learning a programming language is challenging. Even one of the first –but crucial– concepts to learn, variables, is hard to grasp. Variables can represent different roles and functions within a code and need to be named appropriately to support code comprehension and debugging.

We have examined sequences from the ligand-binding domain of the nicotinic acetyl choline receptor (nAChR) in 148 vertebrate species. We are in interested in this receptor because the α-neurotoxins of many venomous snakes binds to this receptor in its location at the neuromuscular junction in all ve…

Op 18 september 2019 verdedigde Huw Llewellyn zijn proefschrift 'An Institutional Perspective on the United Nations Criminal Tribunals: Governance, Independence and Impartiality'. Het promotieonderzoek is begeleid door promotoren prof.dr. N.M. Blokker en prof.dr. L.J. van den Herik.

Promotores: S.J. Edixhoven, P.Parent

The research presented in this thesis concerns one of the most important questions in software engineering of our time: how can we make sure that software is free from memory safety bugs?

In this dissertation non-parametric Bayesian methods are used in the application of robotic vision.

This study has been carried out in the community of Sukamiskin, a kelurahan (‘village’) in Bandung, the Capital of West Java Province, located in the Sunda Region of Indonesia.

In this special edition of Information Polity there is a focus on the transparency challenges of using algorithms in government in decision-making procedures at the macro-, meso-, and micro-levels.

How can we broaden youth participation in STEM Learning

How does one become a guest author for Nobel Prize winner Dr. Denis Mukwege Foundation? One of our alumni, Mariasole Forlani, can tell you all about it.

Een internationaal team van sterrenkundigen waaronder ook Leidse wetenschappers publiceert het beeld van een jonge ster met een omringende stofschijf die nog steeds gevoerd wordt vanuit de omgeving. Het verschijnsel rond de ster SU Aur kan verklaren waarom zoveel exoplaneten niet netjes uitgelijnd zijn…

Astronoom Jos de Boer heeft in Nice de Chesneauprijs in ontvangst genomen voor zijn onderzoek naar zogeheten protoplanetaire schijven. De prijs wordt toegekend aan het beste sterrenkundige proefschrift op het gebied van hoge ruimtelijke resolutie. ‘Ik zie het als een goede kans om over mijn onderzoek…

Today, knowledge is the most crucial element to stimulate organizational competitiveness and economic development.

The origin and evolution of galaxies are closely linked to many different physical phenomena.

This thesis is is made of three parts. The first part describes a generalization of the Chabauty's method, that can be used to determine the rational points of a curve such that s+g>r+1, where g is the genusof the curve, r is the rank of the Mordell-Weil group of the jacobian of the curve and s is…

Lipid signaling is an essential biological event/process in a plethora of pathophysiological conditions. The underlying idea of this thesis is that many of the roles and the complex interplay of the individual signaling lipids in inflammatory processes and related conditions in health and disease is…

Dit op casestudies gebaseerde Engelstalige boek over multivariate analyse voor gevorderde studenten in de geesteswetenschappen legt de nadruk op beschrijvende, exploratieve analyses van verschillende soorten datasets uit een breed scala van subdisciplines, waarbij het gebruik van multivariate analyse…

Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt

A plasma is an ionized gas with very low electrical resistivity. As such, magnetic field lines are 'frozen in' and move with the fluid. Magnetic field lines that are linked, knotted and tangled, cannot be undone by the fluid motions.

We are living in an information era where the amount of image and video data increases exponentially.

Glycosidases are important enzymes in the turnover of polysaccharides and glycoconjugates, and are involved in a range of human pathologies including genetic disorders such as Gaucher and Pompe disease, but also in various cancers.

This thesis is largely an experimental study on the formation of solid-state simple and complex organic molecules in the H2O-rich and CO-rich ice phases of dense interstellar clouds and dark cores.

Binnen het brede netwerk van de Universiteit Leiden neemt het instituut deel aan onderzoek binnen de volgende profileringsgebieden:

This thesis discusses the discovery potential of Intensity Frontier experiments.

This thesis focused on the exploration of monolayer graphene as a membrane in direct methanol fuel cell (DMFC) applications, with improvements achieved through plasma exposure or damage- free chemical functionalization.

This thesis introduces the concept of

Reinforcement learning is a framework that enables agents to learn in a manner similar to humans, i.e. through trial and error. Ideally, we would like to train a generalist agent capable of performing multiple tasks and achieving various goals.

Promotor: S.J. Edixhoven

We showed that constitutive and inducible chemical and morphological defenses against Western flower thrips differ between tomato and chrysanthemum plants.

Gold nanoparticles show surprisingly strong interactions with light in the visible range, which can be divided into scattering, absorption, and photoluminescence.

An algorithm is discussed to compute the exponential representation of principal units in a finite extension field F of the p-adic rationals.

Drug-target binding kinetics determine the time course of the central event in pharmacotherapy: Drug-target interaction.

Freshwater biodiversity has been threatened by eutrophication due to excessive nutrients in the environment. Releasing the freshwater species from such pressures requires efforts from industry and manufacturers to avoid emissions to vulnerable and high-risk regions.

This thesis consists of three papers that are centered around the common theme of Hausdorff uo-Lebesgue topologies and convergence structures on vector lattices and on vector lattices and vector lattice algebras of order bounded operators.

The main object of study in this thesis is an Arakelov inequalitywhich bounds the degree of an invertible subsheaf of the direct image ofthe pluricanonical relative sheaf of a semistable family of curves.

Forming at the nodes of the Cosmic Web and growing hierarchically via mass accretion, galaxy clusters are the largest virialized halos in our universe, composed of dark matter (DM; ≥85%), ionized hot plasma in the intracluster medium (ICM; ≥10-15%), and galaxies (≥1-5%).

This thesis provides explicit expressions for the density functions of absolutely continuous invariant measures for general families of interval maps, that include random maps and infinite measure transformations, not necessarily number systems.

In this thesis, we aim to shed light on the diverse and often opposing roles of integrin α3β1 in cancer.

This thesis covers several aspects of quantum algorithms for near-term quantum computers and its applications to quantum chemistry and material science.

This thesis focuses on amyloid proteins, a class of proteins that convert into amyloid fibrils.

Explaining treatment response variability between and within patients can support treatment and dosing optimization, to improve treatment of individual patients.

This thesis investigates the evolution and fate of gaseous exoplanets, which are continuously shaped by stellar activity across both short and long timescales.

Supply risks are not new. But the aggravation of power conflicts on the international stage coupled with global shifts towards energy transition and digitalization has triggered the next supply risk research era.

Detecting nanoscopic objects plays an important role in nanoscience in particular, in the rapidly growing field of nanobiology. The forebear to modern super-resolution microscopy for single molecule investigation, is fluorescence microscopy.

Promotor: Prof.dr. J.P. Abrahams

Soil biodiversity is of great importance for the maintenance of multifunctionality in terrestrial ecosystems.