The intestinal bacterium E. coli can adapt to changes in its surroundings. Leiden scientists have discovered how the H-NS protein makes this possible. This new knowledge can be an important starting point in combatting bacteria and diseases such as peritonitis. Publication 2 October in the journal e…

The chain that supplies patients with new medicines consists of various complex links: from fundamental research to clinical tests and production. This entire chain is represented in Leiden. Leiden University, the Leiden University Medical Center (LUMC), and the companies on the Leiden Bio Science Park…

New technology offers many new possibilities for research, such as on dementia. ‘Organ-on-a-chip’ is a new technology in which small bits of organ are grown out of stem cells on a small plastic plate. A small piece of blood vessel, heart or nerve offers many new possibilities for research, such as…

In 2020, Leiden University launched its stimulated interdisciplinary programs, including one focused on regenerative medicine.

Getting personal

The INTERACT project strive to unlock the enormous biotechnological potential of microbes, leading to sustainable crop productions systems.

Regenerative medicine is a new way of treatment that helps impaired cells, tissues, and organs work well again. We do this by repairing, replacing, or restoring cells, tissues, and organs after damage from illness or injury. This includes treating long-term diseases such as diabetes, kidney diseases,…

The Basics and Applications to Plant Sciences will be held physical. See below for more information.

What is my contribution to the world? This is what students and researchers at Leiden University College The Hague (LUC) ask themselves every day. They want to make a difference with their teaching and research in the four global challenges of ‘Peace and Justice,’ ‘Sustainability,’ ‘Diversity’ and ‘…

Providing each cancer patient with the right treatment remains a challenge. Oncode Accelerator aims to change this by innovating the way we develop cancer treatments, thus ensuring the patient is at the heart of the process. Leiden University, the LUMC and other partners will implement this new way…

The Leiden University Medical Center (LUMC) is committed to improving healthcare and the health of individuals. The LUMC staff put this mission into practice on a daily basis with their leading research, cutting-edge teaching and optimal, innovative healthcare.

La Grande Roche is one of the rare archaeological sites that preserved a long sequence of deposits formed at the time of contact between late Neandertals and early Homo sapiens.

We aim to provide new insights relating to the spectacular multi-cellular life cycle of streptomycetes and other actinobacteria.

Treatment with special stem cells seems to be a good option for suppressing the immune system in organ transplants. Researchers are trying to learn from processes that take place in the human body during pregnancy.

What is the role of stress and stress-related hormones in emotion regulation?

Microbes influence and respond to other organisms. This theme explores the dynamic relationships within plant and animal microbiomes, and the immune responses that govern host defense. Using model systems such as zebrafish, insects, and plants, we investigate fundamental processes and engineer microbes…

What are key regulators of plant ageing that can reverse ageing in plants (rejuvenation), and how can we use this knowledge to improve crop plants?

We aim to unravel the complex and intertwining regulatory systems that control development and antibiotic production in streptomycetes.

Combining different disciplines, researchers work together to formulate innovative solutions to societal problems.

Medicines do not follow the one size fits all principle, because genetic differences can influence their efficiency. That is what research by PhD candidate Julia Hillger shows. She defends her PhD dissertation Take it Personal on Thursday 7 December.

Publication by: Anouk Wezel, Sabine Welten, Wida Razawy, Max Lagraauw, Margreet de Vries, Eveline Goossens, Martin Boonstra, Jaap Hamming, Ekambar Kandimalla, Johan Kuiper, Paul Quax, Yaël Nossent and Ilze Bot. Annals of Surgery. 2015;262:841-848.

Producing offspring of a crop without sowing and that is even bigger than the parent plant. According to Leiden researchers this can be achieved by overstimulating a single gene that rejuvenates cells, including bringing them back to the embryonic phase.

Single-celled organisms have stiffer DNA than multicellular lifeforms like humans and rice. Theoretical physicists managed to simulate the folding in full genomes for the first time to reach this conclusion. Publication in Biophysical Journal on February 7.

People with relatively high levels of lipids in their blood are less likely to develop allergic conditions such as eczema and asthma. These lipids cause genes that play a key role in allergic reactions to be less active. Researchers from the Leiden University Medical Center (LUMC) have published an…

Listening and Looking with dr. Janneke Wesseling and dr. Marcel Cobussen

Multiple identities of elites and ‘commoners’ viewed through the lens of crafting from the Chalcolithic to the Iron Ages in Europe and the Mediterranean

Lecture

Researchers at LUMC have made a breakthrough in understanding PALB2 mutations, an important cause of hereditary breast cancer.

Personality is genetic in zebrafish: risk-taking parents have risk-taking children. These are the findings of research by Christian Tudorache and his team published in BMC Neuroscience.

Proactive zebrafish appear to have a much stronger wake-sleep rhythm than reactive fish. In the most reactive fish, rhythmicity appears to be lacking completely. This is shown with research by Leiden biologists, published in December 2018 in the journal BMC Biology.