Proactive zebrafish appear to have a much stronger wake-sleep rhythm than reactive fish. In the most reactive fish, rhythmicity appears to be lacking completely. This is shown with research by Leiden biologists, published in December 2018 in the journal BMC Biology.

Within the same species of butterfly many different wing patterns can occur. How is this possible? According to researchers Ben Wielstra and Emma Berdan, of the Institute of Biology Leiden (IBL), the answer lies within supergenes. A supergene is a part of a chromosome that contains many strongly linked…

Majid Khan, born and raised in Pakistan, left his wife and daughter behind to do research in Leiden. After obtaining his PhD, the Netherlands has taken a special place in his heart. ‘Biking in the rain and wind was weird. But I loved it.’

Mirjam Sombroek, Aart Hendriks and Martine de Vries (LUMC) will work on mapping the ethical and legal aspects of gene therapy. The aim is to establish a best practice of how society can best deal with these therapies. For example with guidelines on how to regulate, reimburse and make these therapies…

Scientist looked for the genetic footprint of fire use in our genes, but found that our prehistoric cousins - the Neanderthals - and even the great apes seem better at dealing with the toxins in smoke than modern humans.

Leiden evolutionary biologist Maurijn van der Zee has co-operated on an enormous international project to describe the genetic material of the pea aphid Acyrthosiphon pisum. The more than 100 authors involved in the project have published their findings in the online magazine PLoS Biology.

Aad van der Vaart, professor of stochastics at Leiden University, has been awarded the NWO Spinoza Prize for his groundbreaking research in statistics. Van der Vaart conducts fundamental research on models that can help, for instance, to identify genes that play a role in cancer.

PhD defence

With the search for new antibiotics becoming increasingly urgent, artificial intelligence offers valuable help. Smart software developed by Leiden PhD candidate Alexander Kloosterman searched genomes of bacteria and found clusters of DNA that code for proteins that have an antibiotic effect. ‘This new…

The Leiden University Medical Center (LUMC) will start construction this year of the largest non-profit stem cell and gene therapy facility in the Netherlands, and one of the largest facilities in Europe. NECSTGEN – the Netherlands Center for the Clinical Advancement of Stem Cell and Gene Therapies…

The DNA of young people is regulated to express the right genes at the right time. With the passing of years, the regulation of the DNA gradually gets disrupted, which is an important cause of ageing. A study of over 3,000 people shows that this is not true for everyone: there are people whose DNA appears…

‘It's where disciplines intersect that the most exciting scientific questions arise.' This was the message given by John van Noort, Professor of Biophysics, in his inaugural lecture. His own research is at the interface between biology and physics. Inaugural lecture 23 April.

Leiden Biology student Lukas Kiefer has won the Unilever Research Prize 2018 for his research into efficient production of a new antibiotic. Kiefer: ‘I want to make biological medicines available to people in need.'

Plant biologist Pingtao Ding, assistant professor at the Institute of Biology Leiden (IBL), has received a 2.4 million European grant from the European Research Council (ERC). This ERC Starting Grant for promising young researchers allows him to unravel the molecular mechanisms by which plants resist…

We already know a lot about genetics and the risk of breast cancer. But much still needs to be done in breast cancer genetics to improve the prognosis and make sure women at high risk aren’t missed. This is what Professor by Special Appointment Marjanka Schmidt will say in her inaugural lecture on 4…

Leiden University is partner of the Netherlands Centre for One Health (NCOH). This initiative brings together leading academic research institutes in the Netherlands in an open innovation network that responds to the theme: One Health. NCOH interviewed Doris van Bergeijk: PhD student of the project…

New research published in the Journal of Leukocyte Biology suggests that these changes to the behavior of the immune system are persistent and can continue even after diet is improvedAlmost everyone knows that improving your eating habits will most likely improve your health. What most people may not…

Collaborating and learning from other fields – that is what bioinformatician Hannah Augustijn enjoys most about doing research. During her PhD at Leiden University, she developed new ways to search within bacteria for the antibiotics of the future.

Medicines are becoming increasingly precise and innovative, but at the same time increasingly expensive. With their innovations, it is up to universities to increase competition, thus causing prices to drop. This is what newly appointed Professor of Biomolecular Analysis Hubertus Irth argues. His inaugural…

What socio-cultural transformations did indigenous communities in the Lesser Antilles undergo from the late precolonial to the early colonial period in response to Amerindian­ European-African cultural encounters? How did Amerindian populations realign themselves in response to the colonisation…

A new analysis of the king cobra genome by Michael Richardson, Christian Henkel (IBL) and collaborators at the IBL and Naturalis, Helsinki and Singapore has been published in

Mathematician Stéphanie van der Pas and psychologist Sandy Overgaauw have been nominated for the New Scientist science talent competition, a prize for the most talented scientist in the Netherlands and Flanders.

Neurologist Professor Michel Ferrari has been awarded the Spinoza prize. 'In biomedical research you can only make breakthroughs at the borders between sciences,' according to Spinoza, doctor and scientist. 'This prize is proof that co-operation works.' Together with clinical and fundamental researchers…

Robert Ietswaart does research into gene regulation at the famous Harvard Medical School in Boston. He developed an algorithm to better predict whether a candidate medicine is going to produce side effects. He studied mathematics and physics in Leiden, and gained his PhD in computational biology in…

Data science and statistics are closely linked, says Spinoza laureate and Stochastics professor Aad van der Vaart. We talk with him about the big data hype, genome research and collaboration with other disciplines. ‘Statistics helps wherever data is not perfect.’

Professor Annemieke Aartsma-Rus from Leiden University Medical Centre (LUMC) has received the Ammodo Science Award for her research into the muscular disease Duchenne.

He brings order to chaos and analyses satellite swarms. During his PhD research, mathematician Oliver Nagy delved into random networks and how they reach equilibrium. Along the way, he also developed a handy tool. This knowledge is valuable for calculations related to communication networks.

Doğukan Yilmaz chose a study that aligned with his favourite subjects, and it paid off. For his bachelor thesis, he developed a new model to better predict an important chemical reaction. ‘On the edge of what is possible at the bachelor level,’ his supervisors write. Thanks to his impressive achievements,…

On 22 November, Leiden scientist Jan Vonk received an ERC starting grant for his research on the building blocks of mathematics. This grant is not his first this year: in fact, this July Vonk also received a Vidi from NWO. Four questions to the scientist who got two grants this year.

Conference, International Seminar, Hybrid

Conference, International Seminar, Hybrid

PhD defence

PhD defence

In breast cancer, metastasis rather than the primary tumour is the cause of death. A lack of oxygen in the tumour cells promotes this metastasis, accompanied by a reprogramming of the cell's metabolism. PhD candidate Qiuyu Liu investigated these alterations to get more knowledge about the actionable…

Lecture

Leiden biophysicist Stefan Semrau was granted an NWO Vidi earlier this month. He will use the grant to study the role of electricity in embryonic development and tissue regeneration.

Zsuzsa Bakk has been selected as the winner of the 2016 Distinguished Dissertation Award of the Classification Society for her thesis entitled 'Contributions to Bias Adjusted Stepwise Latent Class Modeling'.

Discover the unique Vital Interests course in the BSc Security Studies programme, featuring an inspiring session on climate diplomacy with Dutch UNFCCC negotiators.

PhD defence