861 search results for “gene theory” in the Public website
-
PhD-vacancy at the IBL on the neurogenomics of vocal learning
This project on the role of FoxPs in vocal perception and production learning is part of nine PhD-positions funded by the NWO Gravitation Programme which was granted to the Dutch Research Consortium 'Language in Interaction'
-
Biomolecular analyses of skeletal remains in the circum-Caribbean across the historical divide (A.D. 1000-1800)
As part of the NEXUS1492 project, this project will use ancient DNA techniques to shed new light on the demographic and health history of the Caribbean and the impact of European colonization on indigenous communities in the region.
-
SuperCode
SuperCode: Sustainability PER AI-driven CO-DEsign
-
Vision and Mission
The need for novel drugs as well as innovations in their development and application is as urgent as ever. Below we present our vision , mission, and our key research areas.
-
Cancer Therapeutics and Drug Safety
In this research group, headed by Bob Van de Water, cell signaling programs that underlie adverse drug reactions as well as cancer development and progression are unraveled. Adverse drug reactions involve cell injury in critical target organ cells which leads to the activation of cellular stress response…
-
Physics and Engineering Approaches to Biomedicine and Pharmacology
Mashaghi lab conducts research at the interface of physics, engineering and biomedicine. We develop and use theoretical and experimental approaches to address basic and applied research problems.
-
United States
This is an Erasmus+ International Credit Mobility project of Leiden University Medical Center with Boston Children’s Hospital in the USA.
-
Research lines
Physics and Engineering Approaches to Biomedicine and Pharmacology
-
Formulation and Characterization of Vaccines
Vaccines are an extraordinary category of biopharmaceuticals. They are usually prophylactic and come in many types, from whole bacteria to peptides and nucleic acids. They are very cost effective and almost every human on the planet is vaccinated. The latter mandates that vaccines have to be extremely…
-
Image-based Computational Biology
In this research group, led by Dr. Joost Beltman, the aim is to employ mathematical and computational dynamical modelling approaches in order to quantitatively and mechanistically understand the dynamical behaviour and regulation of intracellular networks of genes, proteins and metabolites as well as…
-
Awards and Grants 2022
An overview of awards and prizes granted to our staff and students in 2022, as well as special appointments at Leiden University and other institutions.
-
Statistics & Data Science (MSc)
The master’s programme Statistics & Data Science provides students with a thorough introduction to the general philosophy and methodology of statistical modelling and data analysis. The programme has two specialisations: Data Science and Statistical Science.
-
Research
Research at the Macromolecular Biochemistry group is comprised of the following research themes:
-
PhD Theses
A full overview of MacBio PhD Theses.
- Research Dossiers
-
docARTES
docARTES is a doctoral programme for performers and composers. It offers a unique environment for critical reflection on musical practice.
-
New STW-grant for study on crop protection
Dr. Kirsten Leiss and Prof. Peter Klinkhamer received 900.000 euro’s from “Stichting Toegepaste Wetenschappen (STW)” and the company “Rijk Zwaan” to develop plants that are resistant to thrips, a major agricultural pest all over the world.
-
Dialogues Between Artistic Research and Science and Technology Studies
'Dialogues Between Artistic Research and Science and Technology Studies', edited by Henk Borgdorff, Peter Peters and Trevor Pinch, will be published by Routledge on November 18
-
Coarsened Data in Theory and Practice: Challenges, Considerations and Opportunities
PhD defence
-
Advancing AAV5-Mediated Gene Therapy for Brain and Liver Indications: Preclinical Assessment of Biodistribution, Efficacy, and Safety in Animal
PhD defence
-
Catia AntunesFaculty of Humanities
-
Veni awards for seventeen young Leiden researches
The Netherlands Organisation for Scientific Research (NWO) has awarded Veni funding to seventeen researchers who recently obtained their PhD. This award offers promising young scientists the opportunity to develop their own ideas over a period of three years.
-
Developing new therapies to fight muscle disease
Biophysicist Alireza Mashaghi and his collaborators are taking up the fight against muscular dystrophy: genetic disorders that cause muscle weakness. They want to inhibit the clumping of proteins that results in toxic aggregates. For this, the team receives 550,000 euros from Health Holland. The team…
-
ERC Consolidator Grants for Leiden researchers
Five Leiden researchers have been awarded a Consolidator Grant by the European Research Council (ERC). This grant of up to two million euros will enable them to continue and expand their scientific research.
-
LUMC signs international agreement on developing Advanced Therapy Medicinal Products
Skåne University Hospital, Lund University and Leiden University Medical Center will work together to expand their research, teaching and development relating to Advanced Therapy Medicinal Products. That is the essence of a Memorandum of Understanding signed at SciLifeLab near Stockholm on Wednesday…
-
New traffic controller discovered on DNA railway
A new LUMC study has changed our understanding of how cells work. Researchers have discovered that the CFAP20 protein acts as a kind of ‘traffic controller’ on DNA. Without this protein, chaos ensues, potentially causing cancer. Their findings have been published in the prestigious journal Nature.
-
King of Sweden visits Leiden University
Collaborating in drug discovery and health research was the goal of a visit to the Leiden Bio Science Park on 14 May by a Swedish delegation including His Majesty King Carl XVI Gustav of Sweden. The delegation visited Leiden University’s Faculty of Science.
-
Hunt for fundamental insight into and treatment for cancer
To develop good cancer treatments, we need to know much more about how malignant tumour cells develop. Professor Ewa Snaar-Jagalska looks at not just the effect of medication on isolated cells but also the behaviour of cancer cells in their tissue environment. Inaugural lecture on 11 December.
-
New cell therapy facility at Leiden Bio Science Park
American pharmaceutical company Bristol Myers Squibb will be building a new (CAR-T) cell therapy facility in the Oegstgeest part of the Leiden Bio Science Park. The company will manufacture and develop CAR T-cell therapy for patients with blood cancer (leukaemia), for example.
-
Movements of steroid receptors inside the cell nucleus unraveled
Advanced fluorescence microscopy techniques have revealed how steroid receptors move inside the nucleus. The results were published by a team from Leiden University and the Erasmus Medical Center in Rotterdam, led by IBL-researcher Marcel Schaaf.
-
New insights for improved pertussis vaccines - Press release -
Researchers in Bilthoven, The Netherlands, have recently unraveled the defense against whooping cough bacteria in unprecedented detail. The outcome of the project, conducted at Intravacc (Institute for Translational Vaccinology) in Bilthoven, provides opportunities for a new approach in the development…
-
Leiden scientists map cell types in fetal kidney
Kidney failure is a serious issue because kidneys cannot regenerate themselves after injury. A possible solution consists of artificially growing healthy kidney tissue. To achieve that, scientists first need to understand kidney development during the earliest stages, in the fetus. Leiden researchers…
-
First clinical trial with genetically modified malaria vaccine completed
In an innovative study, Radboudumc and LUMC jointly tested a candidate vaccine based on a genetically weakened malaria parasite. The results of this clinical trial, published in Science Translational Medicine, show that the vaccine is safe and elicits a defense response against a malaria infection.
-
Matching medication to DNA leads to 30% fewer side effects
According to the LUMC, patients experience 30% fewer serious side effects when medication doses are tailored to their DNA.
-
Rational points and new dimensions
How can you solve equations that define not ‘just’ curves, but also two-dimension surfaces or even higher-dimensional objects? That’s the big question that mathematician Martin Bright and his team will be trying to answer. They’ve received a NWO Science-XL grant of 2.8 million euros.
-
Bartosz KreftFaculty of Science
-
Vasilii BokovFaculty of Science
-
Túlio De Amorim Da RosaFaculty of Humanities
-
Liam ChungFaculty of Science
-
Franziska BauerFaculty of Humanities
-
Hans-Dieter HiepFaculty of Science
-
Céline FietzFaculty of Science
-
Twan KoperbergFaculty of Science
-
Silke HenkesFaculty of Science
-
Irene Urrutia SchroederFaculty of Humanities
-
Michael YonliFaculty of Science
-
Felix FrohnertFaculty of Science
-
Arend-Jan QuistFaculty of Science
-
Tony FosterFaculty of Humanities
-
Katinka ZevenFaculty of Humanities