2,109 search results for “stam cell biology” in the Public website
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Summer School: Frontiers of Modern Physics
This is the physics summer school of Leiden University. It is part of the Leiden Institute of Physics (LION). The summer school is intended for Bachelor (BSc) students in physics. It covers topics from quantum matter and optics, to biological & soft matter physics and cosmology and theoretical physics.…
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Lemay Lab - Iontronics
Research in the Lemay Lab concentrates on Iontronics: the physics of mixed electronic-ionic charge transport.
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Pingtao Ding -
Tom van der Wel -
Paul KesslerFaculty of Science
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The aging B cell landscape in atherosclerosis
PhD defence
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Exploring and exploiting CD8+ T cell proliferation
PhD defence
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Immune cell networks in Inflammatory Bowel Disease
PhD defence
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Vera van Noort appointed “Van der Klaauw professor”
Vera van Noort, professor in Computational Systems Biology at the KU Leuven (Belgium), is appointed holder of the rotating chair “Van der Klaauw Professor” for the year 2015-2016 at the Institute of Biology. Holders of the chair bring inspiring research and teaching in theoretical biology to the University.…
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3D-printed mini-tumours: a leap forward in improving cancer immunotherapy
Leiden researchers have developed a groundbreaking model to advance cancer immunotherapy. Using a 3D printer, they create mini-tumors within an environment that closely mimics human tissue. They have also developed a method to monitor real-time interactions of these mini-tumours with immune cells during…
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Unilever Research Prize 2015 for Biologist Flor Rhebergen
On December 4th, Flor Rhebergen received the 2015 Unilever Research prize for his study achievements at the IBL for his outstanding work in the field of Evolutionary Biology. Flor Rhebergen received the “Ovum” sculpture and was awarded €2.500.
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What DNA in droppings can reveal about an animal’s diet
Imagine scanning lion dung or a mouse dropping and instantly knowing exactly what and how much the animal has eaten. Thanks to new DNA techniques, this is becoming increasingly feasible. PhD student Kevin Groen tested how effective these techniques are at unraveling the diets of wild animals.
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Organisation
The Leiden Academic Centre for Drug Research (LACDR) is responsible for the research and education in Bio-Pharmaceutical Sciences carried out at Leiden University.
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Deep imaging
A computer can look at, and learn from, many more images than a human specialist. AI systems are rapidly becoming indispensable for medical and biological applications. But they still have to learn how to explain their decisions.
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Inverse Agonism and Constitutive Activity
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Formulation and Characterization of Vaccines
Vaccines are an extraordinary category of biopharmaceuticals. They are usually prophylactic and come in many types, from whole bacteria to peptides and nucleic acids. They are very cost effective and almost every human on the planet is vaccinated. The latter mandates that vaccines have to be extremely…
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LED3 Lecture: Live-cell protein chemistry in health and disease
Lecture
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Embryos of the bitterling perform a somersault. This teaches us something new about natural selection
Even embryos can become embroiled in an evolutionary arms race with another species. Leiden biologists demonstrate this with larvae of the rosy bitterling that parasitize the gills of freshwater mussels. They published their research on February 19 in PNAS.
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Structural Landscapes of the Prenatal and Emphysematous Lung at the Single-Cell Level
PhD defence
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Joan van der Waals colloquium
The Joan van der Waals colloquium is an ongoing bi-weekly lecture series.
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Research
Tuberculosis causes 1.5 million deaths yearly and anti-tuberculosis therapies are threatened by emergence of drug resistance. Development of innovative drug combinations should be accelerated with the use of translational pharmacological models. Moreover, host-directed therapies (HDT), which stimulate…
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Imaging and Bioinformatics
On the basis of the characteristic aspects of a picture, certain computers can tell us what the picture is showing. They can learn this in the same way that young children are able to learn to recognize images. Further improving these techniques opens the way to a whole range of new applications. Biology…
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Why Leiden University?
The Biological- and Soft-Matter Physics Master specialisation is one of the two programmes Leiden offers in experimental Physics. The programme can to a high degree be tailored to individual needs and interests.
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Research
Physicists at the Leiden Institute of Physics (LION) conduct fundamental research into physical phenomena. They are inspired by curiosity and the desire to know more about the world in which we live. This research has always paved the way for new practical applications. These are something that the…
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Biophysical Organic Chemistry
The long term goal of the Biophysical Organic Chemistry/SSNMR group, headed by Prof. Huub de Groot, is to reach an understanding of structure, dynamics and functional mechanisms of membrane proteins and self-organized biological assemblies and to translate this knowledge into new concepts for nano-devices,…
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Kraft Lab - Self-assembly in Biological and Soft Matter
Research in the Daniela Kraft Lab focuses on self-assembly in biological and soft matter systems, ranging from anisotropic colloidal particles to lipid membranes, emulsions, and viruses.
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Vision and Imaging
On the basis of the characteristic aspects of a picture, certain computers can tell us what the picture is showing. They can learn this in the same way that young children are able to learn to recognize images. Further improving these techniques opens the way to a whole range of new applications. Biology…
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How protein modifications cooperate to repair DNA
How do protein modifications work together to repair DNA, and what can we learn about these interactions to better understand disease?
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Research
Combining different disciplines, researchers work together to formulate innovative solutions to societal problems.
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IBL Researcher Secures EU Funding for Groundbreaking Solar-to-X Technology
Cyanobacteria are promising microorganisms to advance sustainable biotechnology, since they can be genetically engineered to convert carbon dioxide and light energy into valuable product molecules.
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Divisions
The IBL has four Divisions: Animal Sciences, Plant Sciences, Microbial Sciences and Science Communication and Society.
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GRIPonMASH
GRIPonMASH will address the unmet public health need of reducing disease burden and comorbidities associated with Metabolic dysfunction-Associated Steatotic Liver Disease (MASLD).
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Research
Research at the BPOC/SSNMR group is comprised of the following research themes:
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Protein arginine methyltransferases as modulators of lipid metabolism and inflammation and the relevance for atherosclerosis
Acute cardiovascular clinical events such as myocardial infarction and cerebral stroke represent the major cause of death in Western societies. These pathologies are primarily resulting from atherosclerosis, a progressive condition characterized by the accumulation of lipids, immune cells, and fibrous…
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Histone-DNA assemblies in archaea. Shaping the genome on the edge of life
All life on earth contains DNA, which is used to store biological information. Organisms compact their DNA in order for it to fit inside their cell(s).
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Biological, Soft and Complex Systems
We study the physics of a broad range of biological and soft materials
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Strategies for the improvement of genome editing in Arabidopsis thaliana
Increasing the efficiency of gene targeting (GT) as a genome editing tool in plants has been an important goal in plant biotechnology.
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Photoinduced processes in dye-sensitized photoanodes under the spotlight: a multiscale in silico investigation
With increasing carbon dioxide levels in the atmosphere and their detrimental effect on the global climate, modern society needs to push for more renewable energy sources. Storing widely accessible and abundant solar energy in chemical bonds in the form of molecular fuel via artificial photosynthesis…
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The activation mechanisms of G protein-coupled receptors: the case of the adenosine A2B and HCA2/3 receptors
Promotor: A.P. IJzerman
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Plant BioDynamics Laboratory
The Plant BioDynamics Lab (PBDL) is a laboratory dedicated to experiments designed to develop and validate quantitative mathematical models of dynamical processes in biology. The principal objective of developing these models is to make quantitative predictions about these processes.
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LACDR PhD Portal
The objective of the PhD Education and Supervision program is to educate PhD candidates in becoming professionals who are competent to conduct scientific research in the field of the pharmaceutical sciences independently.
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Structural changes in single chromatin fibers induced by tension and torsion
Promotor: Prof.dr. T. Schmidt, Co-promotor: Dr. ir. S. J.T. van Noort
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Electrochemical and surface studies of the effect of naphthalene-based additives on tin electrodeposition
Tin electrodeposition applications have rapidly evolved in the past 25 years.
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Platinum surface instabilities and their impact in electrochemistry
Hydrogen fuel cells are expected to be pivotal in the energetic transition towards renewable energy sources such as solar and wind power. However, their industrial scalability is severely hindered by the high cost and degradation rate of platinum catalysts, one of their key components. Addressing this…
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Lipids as therapeutic targets for barrier repair in skin diseases
The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.
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Human epidermal lipid biosynthesis in health and disease
How are the epidermal lipid pathways involved in health and disease.
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Structure-affinity relationships (SARs) and structure-kinetics relationships (SKRs) of Kv11.1 blockers
Source: J Med Chem (2015)
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Advanced in vitro models for studying drug induced toxicity
Promotor: Prof.dr. B. van de Water, Co-promotor: L.S. Price
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Coiled-coil mediated liposomal fusion: Asymmetric behaving peptide fusogens
Membrane fusion is a vital process in living organisms and is mediated by zipper-like proteins.