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2,082 search results for “binding study advies bsa” in the Public website

• 
  Elizabeth (Liesbeth) de Lange Professor Predictive Pharmacology

  Faculty of Science

• A chemical biology approach for targeting of ligand-drug conjugates Research output

  Promotores: Prof.dr. H. S. Overkleeft, Prof.dr. G. A. van der Marel

• FragmEndoscopy: Medieval fragments in early modern book spines Research project

  During the early modern period, many medieval manuscripts were cut up into strips of parchment which were reused to reinforce the bindings of newly printed books. Until recently, these reused pieces of medieval manuscripts only came to light when the early modern book binding was damaged and/or subjected…

• Antibiotic Discovery: From mechanistic studies to target ID Research output

  The investigations described in this thesis lay out strategies aimed at advancing antibiotic research and development. The examples presented revolve around two main approaches: understanding drug-target interactions and target identification.

• 
  Channa Li Guest Researcher

  Faculty of Humanities

• About NIMAR The Netherlands Institute Morocco

  The institute is funded by the Ministries of Education, Culture and Science and of Foreign Affairs and by Leiden University. To safeguard the institute’s independence and interests in Morocco, it is part of the Netherlands Embassy in Rabat under Moroccan law. The institute performs its tasks under the…

• 
  Nico Kaptein Professor Emeritus Islam in South East Asia

  Faculty of Humanities

• 
  Peter Verhagen Guest

  Faculty of Humanities

• 
  Ab de Jong Professor Comparative Religion and Religions of Antiquity

  Faculty of Humanities

• 
  Xiao Luo PhD candidate

  Faculty of Humanities

• 
  Boudewijn Walraven Professor emeritus of Korean language and literature

  Faculty of Humanities

• 
  Haneen Omari University lecturer

  Faculty of Humanities

• It's about time Research output

  This thesis explored the molecular pharmacological mechanisms of targeting CB2R via investigation of novel drug discovery concepts such as target binding kinetics, allosteric modulation and biased signaling.

• 
  Maghiel van Crevel Professor of Chinese Language and Literature

  Faculty of Humanities

• LED3 Drug Discovery Case Studies Leiden Early Drug Discovery & Development

  To get a feeling of how we operate at LED3 when it comes to Early Drug Discovery, please browse through our case studies. When you select a case study you’ll find relevant contacts.

• 
  Philomeen Dol Team Leader / Foreign Language Teacher

  Faculty of Humanities

• 
  Henk Schulte Nordholt Professor emeritus Indonesian History

  Faculty of Humanities

• synthesis and application of paramagnetic probes for protein structure studies Research output

  The main subject of this thesis is the design and synthesis of paramagnetic molecules for protein studies with NMR and EPR spectroscopy.

• Affinity and kinetics study of anthranilic acids as HCA2 receptor agonists Research output

  Structure-affinity relationship (SAR) and structure-kinetics relationship (SKR) studies were combined to investigate a series of biphenyl anthranilic acid agonists for the HCA2 receptor.

• 
  Francesca Rosati PhD candidate

  Faculty of Humanities

• 
  Geoffrey Cain PhD candidate

  Faculty of Humanities

• 
  Edegar Da Conceição Savio

  Faculty of Humanities

• 
  Arfi Arfiansyah Affiliated researcher

  Faculty of Law

• 
  Steven Hagers PhD candidate

  Faculty of Humanities

• 
  Amirardalan Emami

  Faculty of Humanities

• 
  Xiong Xiong PhD candidate

  Faculty of Humanities

• Synthesis and biological evaluation of spirocyclic antagonists of CCR2 (chemokine CC receptor subtype 2) Research output

  Source: Bioorg Med Chem, Volume 23, Issue 14, pp. 4034-49 (2015)

• 
  Caroline Fernandes Caromano Researcher

  Faculty of Humanities

• More effective blocking of CCR2 receptor Leiden Early Drug Discovery & Development

  The discovery of new medicines is a tedious and lengthy process. On average, over 10,000 molecules need to be studied for one to become a drug and reach the patient. Part of that process are the very costly clinical trials in humans, and candidate drugs often fail due to side effects or lack of efficacy.…

• Allosteric modulation by sodium ions and amilorides of G protein-coupled receptors Research output

  Promotor: A.P. IJzerman

• Allosteric modulation by sodium ions and amilorides of G protein- coupled receptors Research output

  Promotor: A.P. IJzerman

• Chemical biology of glucosylceramide metabolism: fundamental studies and clinical applications for Gaucher disease Research project

  How can we develop new chemical biology tools and approaches to understand and interfere with glucosylceramide metabolism in relation to Gaucher disease?

• 
  Crewe Williams PhD candidate

  Faculty of Humanities

• Synthesis and applications of cell wall glycopolimer fragments from Staphilococci and Enterococci Research output

  Carbohydrates are present on the surface of bacteria making them suitable antigen candidates for vaccine development. This thesis deals with the synthesis of two carbohydrate-based components; the capsular polisaccharide of S. aureus type 5 and teichoic acids from staphilococci and enterococci speci…

• 
  Judith Frishman Professor emeritus Judaism

  Faculty of Humanities

• 
  Arie van der Kooij Professor emeritus of Biblical Studies

  Faculty of Humanities

• 
  Paula Esteves dos Santos Jordao Lecturer

  Faculty of Humanities

• 
  Sarah Holma

  Faculty of Humanities

• 
  Marat Markert Lecturer

  Faculty of Humanities

• 
  Léon Buskens Director NIMAR

  Faculty of Humanities

• 
  Irene Hadiprayitno University Lecturer International Studies

  Faculty of Humanities

• Agonists for the Adenosine A1 Receptor with Tunable Residence Time. A Case for Nonribose 4-Amino-6-aryl-5-cyano-2-thiopyrimidines Research output

  Source: J Med Chem, Volume 57, Issue 8, pp. 3213-22 (2014)

• 
  Christian Henderson University Lecturer International Relations / Modern Middle East Studies

  Faculty of Humanities

• Bachelor Q&A (English) Leiden Institute of Advanced Computer Science (LIACS)

  On this page you can find answers to frequently asked questions.

• Come and visit us!

  As a university, we offer you the best education you can get. Professors, tutors and lecturers are ready to teach and guide you. But we do more than that. Of course, studying is your own responsibility, but we are happy to help if you need support. You decide what and when; online or on campus. These…

• Allosteric Modulation Research project

  Allosteric modulation has long been recognized as a general and widespread mechanism for the control of protein function. Modulators bind to regulatory sites distinct from the active site on the protein, resulting in conformational changes that may profoundly influence protein function. This concept…

• allosteric modulator induces an anti-inflammatory effect: in vivo studies and molecular mechanism of action Research output

  Source: Mediators Inflamm (2014)

• 
  Pilar Jimenez Galindo Guest

  Faculty of Humanities

• 
  Al Al Farabi Postdoc / Guest

  Faculty of Law

• 
  Tim Wuisman Tutor Bachelor Security Studies

  Faculty of Governance and Global Affairs