In this dissertation iron-based homogeneous catalysts were synthesized, characterized and investigated for water oxidation activity.

Cardiovascular diseases (CVDs) are the leading global cause of mortality. Endothelial dysfunction, an early reversible stage of CVD development, is marked by decreased nitric oxide production linked to Ca2+ influx in endothelial cells.

This thesis presents the first synthetic peptides ADP-ribosylated on serine, threonine, tyrosine, arginine and cysteine.

Indonesia is experiencing various environmental challenges related to its fast economic growth. Therefore, it is necessary to have measurable and applicable indicators to obtain accurate data and information regarding the costs of adverse environmental impacts arising from economic activities to support…

I will give a general introduction to the field of molecular electronics, its history, methods and challenges. I will also introduce the subject of my investigation and provide a brief outlook to the remainder of our thesis.

An international group of scientists, led by Leiden physicist Sense Jan van der Molen, has developed the first switchable molecular diode. You can turn this on and off through humidity. Vice versa, it is a humidity sensor at the nanoscale. Publication on 4 December in Nature Nanotechnology.

Chronic pain, nausea or vomiting due to chemotherapy. If you suffer from such ailments, medicinal cannabis can be a godsend. Though a downside is that it can make patients high. Therefore, Leiden researchers from the Oncode Institute are investigating alternatives that do not make you high. In Nature…

How has migration affected Irish and Italy society since 1945?

Human cells are protecting their proteins from unfolding and aggregating. That's what biophysicist Alireza Mashaghi and his team discovered after seven years of in-depth research into the folding mechanisms of proteins. With an unprecedented approach, the team was able to study the folding of a single…

Promotores: Prof.dr. F.P. Israel, Prof.dr. P.P. van der Werf

The haplolepideous mosses (Dicranidae) comprise about 4000 species distributed over a wide range of habitats, with great gametophytic and sporophytic morphological variation. Their monophyly is well supported by the results of several molecular phylogenetic studies, which shed light on their relationships…

This book connects labour history, global history and the institutional or political history of international organisations.

A Persistent Revolution: History, Nationalism, and Politics in Mexico since 1968

Phospholipase A/acyltransferase 3 (PLAAT3) and PLAAT4 are enzymes involved in the synthesis of bioactive lipids. Despite sequential and structural similarities, the two enzymes differ in activity and specificity.

Fundamental understanding of molecular reactions on metal surfaces is important for improving heterogeneous catalysis.

This thesis is an experimental study of the UV irradiation of the interstellar ice analogues, relevant for the different stages of the star and planet formation sequence.

Mario van der Stelt has been appointed Professor of Molecular Physiology at the Leiden Institute of Chemistry with effect from 1 November 2017.

Stars and planets form within cold, dense clouds of gas and dust drifting through interstellar space. Although dust makes up only a small fraction of this material, it plays a key role in shaping the chemical evolution of these environments.

PhD defence

Hydrogen peroxide (H2O2) generation via electrochemical oxygen reduction is a sustainable production method for this bulk chemical. However, the selectivity of molecular catalysts for electrochemical H2O2 generation has hardly been investigated in a systematic manner, and it is unknown if their stability…

The Leiden Observatory has appointed a new professor. Selena Viti will hold a chair in Molecular Astrophysics. Viti will build a research group that combines different research techniques to unravel the secrets of local and external galaxies. ‘My main ambition is to change the way scientists interpret…

Promotor: Prof.dr. H.L.V. Linnartz

Laboratory, observation and modeling work on the dissociation of polycyclic aromatic hydrocarbons in interstellar environments and the formation of new molecular species through the fragmentation process.

This thesis revolves around the electronic spectroscopy of molecules in the laboratory and the search for the carriers of the diffuse interstellar bands (DIBs).

Catalysis is of extreme relevance in the production of everyday materials and plays a central role in many aspects of our life.

Narrative Science examines the use of narrative in scientific research over the last two centuries.

As of 1 November, Laura Heitman has been appointed full Professor of Molecular Pharmacology at the Leiden Academic Centre for Drug Research (LACDR). Heitman has been working on the understanding and improvement of drug-receptor interactions in early drug discovery. ‘My ultimate aim is to make medicines…

Promotor: Prof.dr. E. Smets, Dr. M. Stech

Promotor: Prof.dr. E.F. Smets

Promotor: Prof.dr. H.P. Spaink Co-promotor: Dr. B.E. Snaar

Leiden based chemistry student and chess grandmaster proposes molecular system for development of artificial leaf

In the current global context, there is a pressing need to address sustainable energy supplies to safeguard our Planet and its ecosystems. The choices made by human society have a significant impact on genetic evolution and climate.

Heterogeneous catalysis is one of the fundamental processes of modern life, being common in industrial refinery and hydrogen vehicles, all the way to the living cell. The dissociation of H2 on Cu(111) is an important benchmark system for studying heterogeneous catalysis, with a large and varied amount…

Mechanical forces are known to play an important role in bacterial colonies. In this dissertation, we study the self-organization at various stages of growing bacterial colonies, and focus on the mechanical effects of cell growth.

We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.

This project aims at describing the Khoisan languages !Ora (Korana/Griqua) and !Ui of South Africa.

This thesis is about the study of hydrocarbons via infrared spectroscopy.

Large areas of space are filled by molecular clouds that consist of gas and dust grains that are the remnants of dead stars. When these clouds start collapsing, the decreasing temperature and increasing density cause gas particles to start accreting onto dust grain surfaces.

The project investigates the changing local context of crime dynamics and the responses by selected international organizations and national governments. It places a major emphasis on security management at the trans-national level by investigating intra-regional security cooperation between Latin America,…