Public leadership received increasing attention, but we still do not understand how the context of public leaders affects leadership. This research project delves into public leaders’ perceptions of the leadership situations they find themselves in, which are characterised by multiplicity – one could…

Anthropogenic change is reshaping ecological systems, raising concerns about increasing transmission of infectious diseases. Among these, mosquito-borne diseases may be particularly sensitive to environmental change, as their transmission depends on vector populations.

This study aims to explore the use of a behavioral-design-based approach in simulating patient flow through EMTs. It provides a dynamic behavioral simulation model to assess the interactions between patients, staff members, and the related dynamic movements/interactions with the health care facility,…

Target selectivity is an important aspect of any drug molecule, and certainly a parameter to be optimized. That is not trivial for a number of reasons. First of all hundreds of drug targets (receptors, enzymes, ion channels) exist, and no single lab in the world has assays for all of them.

The ambition of the Medical Systems Biophysics and Bioengineering group led by Alireza Mashaghi is to develop and use physics and engineering concepts and tools for pathophysiology, diagnostics and therapy.

This dissertation takes an important step in understanding the phenomenon of non-take-up of social support and what it means for contemporary social policies.

Organic amendments applied to agricultural fields can partially offset our carbon emissions to the atmosphere and improve the resilience of agriculture to the effects of climate change. Driving these benefits, however, are complex and poorly understood interactions between organic amendment properties,…

A new research line is the development of liquid biopsy fingerprints to predict early Alzheimer’s disease (AD) stage in human in readily accessible body fluids in human (in collaboration with: Dr. Geert-Jan Groeneveld, CHDR; Prof. Elga de Vries, Free University Medical Center; and others).

This study looks at population response to government containment strategies during initial stages of the COVID-19 pandemic in four high-trust Northern European countries–Denmark, Germany, the Netherlands, and Sweden–with special emphasis on expressions of governmental trust.

The Statistics group is responsible for research and teaching in statistics and data science.

The unit Health, Medical and Neuropsychology offers eduction and conducts research on related fields of Health, Medical and Neuropsychology.

The Covid-19 'infodemic' and conflict resolution by internet platforms.

This thesis describes the development of improved formulations and alternative delivery strategies for polio vaccination.

We know that armed conflict breeds conflict. We also know the political, economic and demographic factors that inform this repetition of conflict. But we do not understand why accumulated conflict risk factors sometimes do and other times do not pay out in more violence. What if we go beyond macro structural…

What are the main trends in family life today? Three stand out: young adults living with their parents for longer, people delaying parenthood and widening inequality between families. How did these trends emerge, and what are their consequences? Leiden experts explain.

This book, edited by Joost Augusteijn, Constant Hijzen and Mark Leon de Vries, explores how democratic regimes have dealt with anti-democratic forces in society, from the late nineteenth to the early twenty-first century.

Designing and synthesizing high-affinity ligands for a given drug target have always been among the more important challenges in the drug discovery process.

PhD defence

Drawing on insights from past and contemporary scholars and world leaders, the report explores the concepts of a new social contract, a new global deal, and networked and inclusive multilateralism introduced recently by Secretary-General António Guterres to help the United Nations better grapple with…

This dissertation aims to provide insight in ethnic prejudice in Chinese-Dutch children and the ethnic socialization context they are exposed to through three social-contextual factors, i.e., parents, children’s books, and the COVID pandemic.

Allosteric modulation has long been recognized as a general and widespread mechanism for the control of protein function. Modulators bind to regulatory sites distinct from the active site on the protein, resulting in conformational changes that may profoundly influence protein function. This concept…

If you'll soon be getting a COVID-19 vaccine, you might just get the Johnson & Johnson (Janssen) one. This vaccine was developed for the most part in Leiden – and this is no coincidence. Watch the animation below about the development of one of the vaccines in the fight against COVID-19.

What Accounts for the Variety of National Policy Responses to the COVID-19 Pandemic in Europe?

Although the world has made tremendous progress in health, education, sanitation and hygiene, global public health challenges still exist. Disparities in health exist between and within nations as evidenced by inequalities in disease burden, mortality, nutrition and environmental well-being. How does…

The 21st century is witnessing a revolution in our understanding of rational points on surfaces and higher-dimensional varieties, and it is in this field that this project lies.

RAWCLIC’s main goal is to develop knowledge on the future raw materials (RMs) demand, supply and associated environmental impacts induced by the energy and digital transitions in the EU, and to support fact-based industry- and policy- decision-making enabling these transitions.

Now and then we organise book launches to present the latest publications, both academic and popular, in our broad field.

What are ‘missing links’ in research on teacher professional development trajectories? We focus on the role and development of teacher facilitators in designing and implementing (collaborative) professional development trajectories.

Annually the Institute of Cultural Anthropology and Development Sociology awards the Speckmann prize for the best Fieldwork NL report, as well as the most accomplished master’s thesis.

Research and design are becoming more and more important in international science education. In The Netherlands, two recently introduced subjects focus on research and design activities in the classroom: O&O (research and design) and NLT (nature, life and technology). This research aims to look at what…

The Faculty of Archaeology at Leiden is the leading academic institute for Archaeology in the Netherlands, and one of the largest in the world. The Faculty is an international front-runner, in the top ten of the QS World University Ranking, at subject level.

The Risk and Regulation Lab from organises events and workshops in Leiden and The Hague. On this page you can read reports of the events that already took place.

The devastating war in Gaza and the ongoing conflict between Israel and Palestine have caused widespread grief and deepened global divisions. With recent escalations in the Middle East further inflaming tensions, our students and staff are understandably worried and concerned. The university shares…

The Netherlands has a long history of mosquito-borne diseases, particularly malaria, until 1970 when it was declared malaria-free.

In 2023, many of our students and staff won great prizes and secured important research grants.

Some examples of AI-research done at Leiden.

Research question

The recognition that there may be more, so-called allosteric binding sites on a given receptor has also fueled our synthetic efforts. Over the last few years we have focused on many drug targets (adenosine A1, A2A and A3 receptors, the mGlu2 receptor and a classic ‘anti-target’, the hERG channel) to…

Key publications of the Cardiovascular Pharmacology group

Key publications of the Predictive Pharmacology group.

Research in the Daniela Kraft Lab focuses on self-assembly in biological and soft matter systems, ranging from anisotropic colloidal particles to lipid membranes, emulsions, and viruses.

What are the goals of healthcare? That very question must be asked more frequently before healthcare-related choices are made. This is what Martine de Vries, Professor of Normative Aspects of Medicine, advocated during her inaugural lecture on Friday, 2 November 2018.

The Food citizens? team has included two post-docs, three Ph.D. candidates and two research assistants working with the Principal Investigator. The Winter School involved nine Masters and Ph.D. candidates from the universities of Bologna, Gothenburg, Kaunas, Leiden, Louvain, Tromsø, Turin and Utrech…

In STAYAHEAD data-intensive approaches are being developed to ”decode the human immunome” with a focus on a global vaccine strategy. They have developed a rapid mass spectrometric test to analyse in real-time large numbers of variants of SARS-CoV-2 and the host immune response, and use these data to…

Knowing how to resolve global problems is one thing, but how do you make sure that it actually happens? That’s the real challenge, because there are powerful movements everywhere that want to reconstruct the walls of nation states. In an attempt to resolve this issue, Leiden researchers are experimenting…