MHC class I and MHC class II molecules present peptides to the immune system to drive proper T cell responses. Pharmacological modulation of T-cell responses can offer treatment options for a range of immune-related diseases.

In this dissertation, we work towards an experiment in which we aim to bring a micrometer sized magnet at the tip of a soft cantilever into a superposition.

The use of N fertilizers has increased worldwide in the past century. While this increased input of N has increased food productivity, it has also contributed to decreases in biodiversity, soil quality and environmental health, including increases in greenhouse gas emissions.

The Institute of Criminal Law and Criminology comprises two departments. One focuses on research and teaching in the field of criminal law and procedure and the other on criminology.

In this thesis, we focus on novel proteins/mechanisms that regulate integrin-adhesion mediated mechano-transduction.

In this thesis, I studied the origin and evolution of the non-thermal radiation in merging galaxy clusters.

This thesis explores squaramide-based supramolecular polymers and hydrogels, enhancing their mechanical strength for 3D cell culture.

Political and social implications of life in a digital age.

This thesis contributes to studying primordial cosmology theories and their detectability in future observations.

The main aim of my Ph.D. thesis is to further explore the value of using early developing zebrafish larvae (up to 5 dpf) as a model to study anxiety-like behaviour and their pharmacological modulation with drugs.

The LUMC iPSC Hotel offers the generation of research grade human induced pluripotent stem cells (hiPSCs) from different tissue sources using state of the art reprogramming techniques.

This thesis investigates the relations between metabolism and anatomy through the use of Magnetic Resonance Imaging (MRI).

Human vocal communication and music perception represent advanced cognitive skills, seemingly innate and universal. These faculties encompass a range of perceptual and cognitive abilities. Cross-species research sheds light on the origins of musicality by investigating whether these traits are shared…

Transport inspectorates are looking for novel methods to identify dangerous behavior, ultimately to reduce risks associated to the movements of people and goods. We explore a data-driven approach to arrive at smart inspections of vehicles.

Promotor: Prof.dr. M. Ubbink

Would you like to apply for the ICCL programme of Leiden University? Great! On this page you will find out how to apply by following our step-by step guide.

During the course of drug discovery translational steps are made.

Louk Rademaker is visiting fellow at Leiden University, Lorentz Institute for Theoretical Physics. He studies theoretical quantum matter physics, connecting the material science to fundamental concepts and methods.

N-acylethanolamines (NAEs), including N-arachidonoylethanolamine (anandamide, AEA), N-palmitoylethanolamine (PEA) and N-oleoylethanolamine (OEA), are signaling lipids that play an important role in different physiological process.

Journal of Imperial and Global Interactions

Choosing a study programme is fun and exciting, but it’s not always easy. Your choice of study is a major decision; after all, it is about your future. At the same time, it’s good to remember that this choice will not determine the rest of your life.

The interdisciplinary AI & Society minor of Leiden University brings together students and lecturers from a wide range of disciplines. Together they look at the impact of AI on society.

The Leiden Institute for Brain and Cognition (LIBC) is a network that stimulates interdisciplinary exchange of knowledge and expertise on topics related to brain and cognition and focuses on science valorisation and outreach.

These four volumes offer students and researchers a rich collection of published works on the history of slavery works by some of the most preeminent scholars in the field.

In Slaving Zones: Cultural Identities, Ideologies, and Institutions in the Evolution of Global Slavery, fourteen authors—including both world-leading and emerging historians of slavery—engage with the ‘Slaving Zones’ theory.

OpenML empowers scientists to conduct transparent, reproducible, and collaborative AI-driven research.

Within the FSW, we have put together a core team with contacts in the individual Institutes and at the Faculty level.

Ti amo Italia! Immerse yourself in the country of Michelangelo, Dante and Prada. Study one of the most popular languages in the world and discover why Italy has filled an exemplary role for so many centuries and still does. As a graduate of the Bachelor's programme Italian Language and Culture you will…

The studies described in this thesis deal with glycosidases, in particular alpha-galactosidases.

This dissertation focused on computational methods based on first principles calculations using the Density Functional Theory (DFT) framework. Emphasis was laid on affordable methods that can provide a tradeoff between computational expense and accuracy.

Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: Dr. L.H. Heitman

In this work we describe three methods to improve the performance of Quantum Field Theory calculations.

Radio jets are important to the evoultion of galaxies. However, it is still not fully understood how a radio jet can be triggered.

Snellius, Niels Bohrweg 1, 2333 CA, Leiden

This thesis investigates the evolution and fate of gaseous exoplanets, which are continuously shaped by stellar activity across both short and long timescales.

There is a need for alternative methods to replace, reduce and refine (3R) animal experimentation. Combining experimental data from high-throughput in vitro studies with in silico modeling is a promising approach to unravel the effect of chemicals on living cells and to gain a better understanding of…

Leiden University Centre for Linguistics (LUCL) is a reputable institute in the field of linguistics, offering excellent research and education opportunities covering a broad range of languages of the world.

FSW building, Wassenaarseweg 52, 2333 AK, Leiden

Hydrogen peroxide (H2O2) generation via electrochemical oxygen reduction is a sustainable production method for this bulk chemical. However, the selectivity of molecular catalysts for electrochemical H2O2 generation has hardly been investigated in a systematic manner, and it is unknown if their stability…

The EEE lectures are a monthly cross-disciplinary lecture series where globally renowned and inspiring thinkers and scientists are invited.

In this thesis, topics relating to the optimization of high-throughput pipelines used for imaging are discussed. In particular, different levels of implementation, i.e., conceptual, software, and hardware, are discussed and the thesis outlines how advances on each level need to be made to make gains…

This thesis describes the design, synthesis, and immunological evaluation of varying (neo)antigenic peptide conjugates containing either a TLR2 or a TLR7 agonist.

Since 1990 Leiden University has awarded the William of Orange medal to individuals of eminent national or international social standing.

Studies in current archaeological applications of remote sensing and non-invasive prospection methods edited by Hans Kamermans, Martin Gojda and Axel G.

The challenge of achieving fast quantification in metabolomics is the presence of severe matrix effects during the MS analysis of complex samples.

We teach several courses in the domain of Mind, Brain, and Education.

FAIRDOM consortium is an open initiative of various partners including funding programmes, large-consortia, institutes, small groups as well as individuals.

One of the major limitations in culturing complex tissues or organs is the lack of vascularization in the cultured tissue. Development of a functional capillary bed could overcome this problem.